岡山大学大学院医歯学総合研究科・医学部・
医学部附属病院

腫瘍・胸部外科学分野

Department of Cancer and Thracic Surgery

欧文著作

原著論文

• Kurose T, Okumura Y, Sato S, Yamamoto Y, Akaki S, Takeda Y, Kanazawa S, Ando A, Date H, Shimizu N, Hiraki Y： Functional evaluation of lung by Xe-133 lung ventilation scintigraphy before and after lung volume reduction surgery (LVRS) in patients with pulmonary emphysema. Acta Med Okayama (2004) 58, 7-15
  
• Kozuki T, Kiura K, Ueoka H, Tabata M, Date H, Hamazaki S, Bessho A, Tanimoto M： Long term effect of gefitinib (ZD1839) on squamous cell carcinoma of the lung. Anticancer Res (2004) 24, 393-396
  
• Toyooka S, Suzuki M, Maruyama R, Toyooka KO, Tsukuda K, Fukuyama Y, Iizasa T, Aoe M, Date H, Fujisawa T, Shimizu N, Gazdar AF： The relationship between aberrant methylation and survival in non-small cell lung cancers. Br J Cancer (2004) 91, 771-774
  
• Katayama H, Ueoka H, Kiura K, Tabata M, Kozuki T, Tanimoto M, Fujiwara T, Tanaka N,Date H, Aoe M, Shimizu N, Takemoto M, Hiraki Y： Preoperative concurrent chemoradiotherapy with cisplatin and docetaxel in patient with locally advanced non-small-cell lung cancer. Br J Cancer (2004) 90, 979-984
  
• Satyanarayana UG, Suzuki M, Toyooka S, Padar A, Toyooka KO, Zern AL, Miyajima K, Takahashi T, Brambilla E, Gazdar AF： Establishment and validation of quantitative Real-time PCR assay for aberrant methylation of 14-3-3 sigma gene in breast and lung carcinoma. Cancer Genomics & Proteomics (2004) 1, 1-8
  
• Hirami Y, Aoe M, Tsukuda K, Hara F, Otani Y, Koshimune R, Hanabata T, Nagahiro I, Sano Y, Date H, Shimizu N： Relation of epidermal growth factor receptor, phosphorylated-Akt, and　hypoxia-inducible factor-1alpha in non-small cell lung cancers. Cancer Lett (2004) 214, 157-164
  
• Suzuki M, Sunaga N, Shames DS, Toyooka S, Gazdar AF, Minna JD： RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells. Cancer Res (2004) 64, 3137-3143
  
• Shivapurkar N, Takahashi T, Reddy J, Zheng Y, Stastny V, Collins R, Toyooka S, Suzuki M, Parikh G, Asplund S, Kroft SH, Timmons C, McKenna RW, Feng Z, Gazdar AF： Presence of simian virus 40 DNA sequences in human lymphoid and hematopoietic malignancies and their relationship to aberrant promoter methylation of multiple genes. Cancer Res (2004) 64, 3757-3760
  
• Hashimoto K, Nakamura K, Fujio H, Miyaji K, Morita H, Kusano K, Date H, Shimizu N, Emori T, Matsubara H, Ohe T： Epoprostenol therapy decreases elevated circulating levels of monocyte chemoattractant protein-1 patients with primary pulmonary hypertension. Circ J (2004) 68, 227-231
  
• Dote H, Toyooka S, Tsukuda K, Yano M, Ouchida M, Doihara H, Suzuki M, Chen H, Hsieh JT, Gazdar AF, Shimizu N： Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer. Clin Cancer Res (2004) 10, 2082-2089
  
• Takahashi T, Shivapurkar N, Reddy J, Shigematsu H, Miyajima K, Suzuki M, Toyooka S, Zochbauer-Muller S, Drach J, Parikh G, Zheng Y, Feng Z, Kroft SH, Timmons C, McKenna RW, Gazdar AF： DNA methylation profiles of lymphoid and hematopoietic malignancies. Clin Cancer Res (2004) 10, 2928-2935
  
• Toyooka S, Shimizu N： Models for studying DNA methylation in human cancer: a review of current status. Drug Discovery Today (2004) 1, 37-42
  
• Ogo H, Ikeda K, Asano N, Sano Y, Date H, Koide N, Shimizu N, Harada M： Suppressed erythropoiesis after ABO-minor-mismatched living-donor lobar lung transplantation. Heart Lung Transplant (2004) 23, 767-769
  
• Zochbauer-Muller S, Lam S, Toyooka S, Virmani AK, Toyooka KO, Seidl S, Minna JD, Gazdar AF： Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers. Int J Cancer (2004) 107, 612-616
  
• Toyooka S, Suzuki M, Tsuda T, Toyooka KO, Maruyama R, Tsukuda K, Fukuyama Y, Iizasa T, Fujisawa T, Shimizu N, Minna JD, Gazdar AF： Dose effect of smoking on aberrant methylation in non-small cell lung cancers. Int J Cancer (2004) 110, 462-464
  
• Toyooka S, Shivapurkar N, Toyooka KO, Reddy J, Miyajima K, Suzuki M, Shigematsu H, Takahashi T, Parikh G, Pass HI, Chaudhary PM, Gazdar AF： Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types. Int J Cancer (2004) 109, 786-792
  
• Yano M, Ouchida M, Shigematsu H, Tanaka N, Ichimura K, Kobayashi K, Inaki Y, Toyooka S, Tsukuda K, Shimizu N, Shimizu K： Tumor-specific exon creation of the HELLS/SMARCA6 gene in non-small cell lung cancer. Int J Cancer (2004) 112, 8-13
  
• Suzuki E, Ota T, Tsukuda K, Okita A, Matsuoka K, Murakami M, Doihara H, Shimizu N： nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation. Int J Cancer (2004) 108, 207-211
  
• Matsuoka K, Tsukuda K, Suda M, Kobayashi K, Ota T, Okita A, Watanabe K, Suzuki E, Murakami M, Doihara H, Shimizu N： The transfection of thymidylate synthase antisense suppresses oncogenic properties of a human colon cancer cell line and augments the antitumor effect of fluorouracil. Int J Oncol (2004) 24, 217-22
  
• Date H, Aoe M, Nagahiro I, Shimizu N： Living-donor lobar lung transplantation for lymphangioleiomyomatosis. Interactive Cardiovascular and Thoracic Surgery (2004) 3, 188-190
  
• Miyaji K, Nakamura K, Maruo T, Saito H, Emori T, Goto K, Date H, Ohe T： Effect of a kink in unilateral pulmonary artery anastomosis on velocities of blood flow through bilateral pulmonary vein anastomoses in living-donor lobar lung transplantation. J Am Soc Echocardiogr (2004) 17, 998-999
  
• Miyaji K, Matsubara H, Nakamura K, Maruo T, Morita H, Saito H, Kusano KF, Emori T, Goto K, Date H, Ohe T： Differences between flow profiles of pulmonary vein anastomoses affected by peripheral atelectasis in cadaveric and bilateral living-donor lobar lung transplantations. J Am Soc Echocardiogr (2004) 17, 1003-1004
  
• Date H, Aoe M, Nagahiro I, Sano Y, Matsubara H, Goto K, Kawada M, Shimizu N： How to predict forced vital capacity after living-donor lobar-lung transplantation. J Heart Lung Transplant (2004) 23, 547-551
  
• Tedoriya T, Date H, Okabe K, Aoe M, Sano Y, Sano S, Shimizu N： Anastomosis of an anomalous segmental vein with the azygos vein in living-donor lobar lung transplantation. J Heart Lung Transplant (2004) 23, 644-646
  
• Ogo H, Ikeda K, Asano N, Sano Y, Date H, Koide N, Shimizu N, Harada M： Suppressed erythropoiesis after ABO-minor-mismatched living-donor lobar lung transplantation. J Heart Lung Transplant (2004) 23, 767-769
  
• Okutani D, Date H, Hayama M, Inokawa H, Okazaki M, Nagahiro I, Sano Y, Aoe M, Shimizu N： The technique of unilateral double lobar lung transplantation in a canine model. J Thoracic and Cardiovascular Surgery (2004) 127, 563-567
  
• Yano M, Toyooka S, Tsukuda K, Dote H, Morimoto Y, Ohata N, Ichimura K, Aoe M, Date H, Shimizu N： SYT-SSX fusion genes in synovial sarcoma of the thorax. Lung Cancer (2004) 44, 391-397
  
• Teramoto A, Tsukuda K, Yano M, Toyooka S, Dote H, Doihara H, Shimizu N： Less frequent promoter hypermethylation of DLC-1 gene in primary breast cancers. Oncol Rep (2004) 12, 141-144
  
• Hanabata T, Tsukuda K, Toyooka S, Yano M, Aoe M, Nagahiro I, Sano Y, Date H, Shimizu N： DNA methylation of multiple genes and clinicopathological relationship of non-small cell lung cancers. Oncol Rep (2004) 12, 177-180
  
• Dote H, Tsukuda K, Toyooka S, Yano M, Pass HI, Shimizu N： Mutation analysis of the BRAF codon 599 in malignant pleural mesothelioma by enriched PCR-RFLP. Oncol Rep (2004) 11, 361-363
  
• Konishi J, Toyooka S, Aoe M, Omura Y, Washio K, Tsukuda K, Shimizu N： The relationship between NY-ESO-1 mRNA expression and clinicopathological features in non-small cell lung cancer. Oncol Rep (2004) 11, 1063-1067
  
• Okita A, Mushiake H, Tsukuda K, Aoe M, Murakami M, Andou A, Shimizu N： Efficiency of lipofection combined with hyperthermia in Lewis lung carcinoma cells and a rodent pleural dissemination model of lung carcinoma. Oncol Rep (2004) 11, 1313-1318
  
• Yasui K, Kanazawa S, Sano Y, Fujiwara T, Kagawa S, Mimura H, Dendo S, Mukai T, Fujiwara H, Iguchi T, Hyodo T, Shimizu N, Tanaka N, Hiraki Y： Thoracic tumors treated with CT-guided radiofrequency ablation: initial experience. Radiology (2004) 231, 850-857
  
• Kinoshita S, Hirai R, Yamano T, Yuasa I, Tsukuda K, Shimizu N： Angiogenesis inhibitor TNP-470 can suppress hepatocellular carcinoma growth without retarding liver regeneration after partial hepatectomy. Surg Today (2004) 34, 40-46
  
• Date H： Lung Transplantation in Japan. Surg Today (2004) 34, 565-568
  
• Nagahiro I, Andou A, Aoe M, Sano Y, Date H, Shimizu N： Intermittent pneumatic compression is effective in preventing symptomatic pulmonary embolism after thoracic surgery. Surgery Today (2004) 34, 6-10
  
• Date H： Experience with cyclosporine in living-donor lobar lung transplantation. Transplant Proc (2004) 36, 349-351
  
• Yoshikawal T, Aoyagi Y, Kodama K, Kamijo T, Yonou H, Yokose T, Ishii G, Oda T, Takamochi K, Nagai K, Nishiwaki Y, Shimizu N, Ochiai A： Topographical distribution of allelic loss in individual lung adenocarcinomas with lymph node metastases. Modern Pathology (2004) 17, 204-213
  
• Kitamura Y, Shimizu N, Aoe M, Date H, Nagahiro I, Andou A： Allowable warm ischemic time to tracheal extraction for allotransplantation of cryopreserved trachea. The Japanese Journal of Thoracic and Cardiovascular Surgery (2004) 52, 169-174
  
• Nagai K, Aoe M, Shimizu N： Rapid response of hepatocyte growth factor at ulmonary ischemia in a rat model. Acta Medica Okayama (2004) 58, 119-125
  
• Yamane M, Sano Y, Shimizu N： Significant changes in the alloantibody after lung transplantation in the cyclosporine treated rat model. Transplant Immunology (2004) 12, 143-150
  
• Fujita T, Ogasawara Y, Doihara H, Shimizu N： Rectal adenocarcinoma metastatic to the thyroid gland. Int J Clin Oncol (2004) 9, 515-519
  
• Shien T, Doihara H, Hara H, Takahashi H, Yoshitomi S, Taira N, Ishibe Y, Teramoto J, Aoe M, Shimizu N： PLC and PI3K pathways are important in the inhibition of EGF-induced cell migration by gefitinib ('Iressa', ZD1839). Breast Cancer (2004) 11, 367-373
  
• Date H, Aoe M, Sano Y, Nagahiro I, Miyaji K, Goto K, Kawada M, Sano S, Shimizu N： Improved survival after living-donor lobar lung transplantation. J Thorac Cardiovasc Surg (2004) 128, 933-940
  
• Kobatake T, Yano M, Toyooka S, Tsukuda K, Dote H, Kikuchi T, Toyota M, Ouchida M, Aoe M, Date H, Pass HI, Doihara H, Shimizu N： Aberrant methylation of p57KIP2 gene in lung and breast cancers and malignant mesotheliomas. Oncol Rep (2004) 12, 1087-1092
  
• Taira N, Doihara H, Hara F, Shien T, Takabatake D, Takahashi H, Yoshitomi S, Ishibe Y, Shimizu N： Less invasive surgery for primary hyperparathyroidism based on preoperative 99mTc-hexakis-2-methoxyisobutylisonitrile imaging findings. Surg Today (2004) 34, 197-203
  
• Takeda M, Otsuka F, Nakamura K, Inagaki K, Suzuki J, Miura D, Fujio H, Matsubara H, Date H, Ohe T, Makino H： Characterization of the bone morphogenetic protein (BMP) system in human pulmonary arterial smooth muscle cells isolated from a sporadic case of primary pulmonary hypertension: roles of BMP type IB receptor (activin receptor-like kinase-6) in the mitotic action. Endocrinology (2004) 145, 4344-4354
  

欧文著作

症例報告

• Ota T, Hirai R, Tsukuda K, Murakami M, Naito M and Shimizu N： Biliary reconstruction with right hepatic lobectomy due to delayed management of laparoscopic bile duct injuries: a case report. Acta Medica Okayama (2004) 58, 163-167
  
• Miyaji K, Matsubara H, Kajiya M, Tani Y, Nakamura K, Morita H, Emori T, Date H, Ohe T： Failure of disopyramide to improve right ventricular outflow tract obstruction after living-donor lobar lung transplantation. Circ J (2004) 68, 1084-1087
  
• Misao T, Yamamoto Y, Nakano H, Toyooka S, Yamane M, Satoh K： Primary thymic adenocarcinoma with production of carbohydrate antigen 19-9 and carcinoembryonic antigen. Jpn J Thorac Cardiovasc Surg (2004) 52, 30-32
  

和文著作

原著論文

• 伊達洋至、築山尚司： 低肺機能患者の手術−肺気腫手術と肺移植−． MB Med Reha (2004) 41, 31-35
  
• 伊達洋至： COPD臨床Q＆A． COPD FRONTER (2004) 3, 287-292
  
• 伊達洋至, 清水信義： 肺移植 今月の治療 (2004) 12, 284-286
  
• 伊達洋至, 清水信義： 心停止後の肺移植． 今日の移植 (2004) 17, 680-682
  
• 伊達洋至、清水信義、藤尾栄起、宮地克維： PPHに対する肺移植． Heart View (2004) 8, 792-795
  
• 伊達洋至, 青江基, 佐野由文, 岡崎恵, 岡部和倫, 清水信義, 宮地克維, 藤尾栄起, 小川愛子, 大江透, 松原広己： PPH患者の肺移植． Therapeutic Research (2004) 25, 2002-2004
  
• 佐野由文： 肺移植における免疫抑制療法． Therapeutic Research (2004) 25, 964-968
  
• 土井原　博義，小笠原　豊，清水信義： 癌の内視鏡手術up to date: 甲状腺癌． Pharma Medica (2004) 22, 17-20
  
• 青江　基、伊達洋至、佐野由文、永広　格、清水信義： 癌の内視鏡手術up to date: 肺癌． Pharma Medica (2004) 22, 27-31
  
• 伊達洋至、永廣　格、青江　基、佐野由文、岡�ｱ　恵、清水信義、宮地克維、藤尾栄起、小川愛子、大江　透、松原広己： PPH患者の肺移植実施の目安と登録時期について． Progress in Medicine (2004) 24, 356-358
  
• 和田昭宏, 野村裕一, 吉川英樹, 柳貞光, 福重寿郎, 河野幸春, 吉永正夫, 伊達洋至, 河野嘉文： Epoprostenol治療後に生体肺葉移植を施行された原発性肺高血圧症の2例． 日本小児循環器学会雑誌 (2004) 20, 552-557
  
• 小川愛子, 松原広己, 藤尾栄起, 宮地克維, 永瀬聡, 中村一文, 森田宏, 斎藤博則, 江森哲郎, 伊達洋至, 清水信義, 大江透： PGI2持続静注療法を施行した肺高血圧症35例の検討． Therapeutic Research (2004) 25, 1965-1966
  
• 小川愛子、松原広己、藤尾栄起、宮地克維、渡邉敦之、永瀬　聡、中村一文、森田　宏、斎藤博則、江森哲郎、伊達洋至、清水信義、大江　透： PGI2持続静注療法中の抗凝固療法について． Progress in Medicine (2004) 24, 310-312
  
• 金澤右, 向上敬, 三村秀文, 田頭周一, 藤原寛康, 平木隆夫, 郷原英夫, 佐野由文, 伊達洋至, 藤原俊義, 清水信義, 横山正尚, 安井光太郎, 生口俊浩, 兵頭剛： 【最先端のIVR】　肺悪性腫瘍のラジオ波治療． 映像情報Medical (2004) 36, 635-640
  
• 伊達洋至： 肺移植の現状． Laboratory and Clinical Practice (2004) 22, 134-135
  
• 青江　基、内藤　稔、土井原　博義、清水信義： 外科領域における内視鏡下手術． 岡山医学会雑誌 (2004) 115, 220-226
  
• 青江　基、清水信義： 肺癌手術とIC． 外科治療 (2004) 90, 160-166
  
• 伊達洋至, 清水信義： 診療の実際と最新のトピックス　COPD外科療法の進歩． 救急・集中治療 (2004) 16, 1325-1330
  
• 永廣　格、清水信義： 胸部外科『緊急治療の最前線』良性縦隔腫瘍 胸部外科 (2004) 57, 784-788
  
• 永廣　格、清水信義： 胸部外科の指針『上大静脈の潅流障害に対する血行再建術における手技上の要点』・討論 胸部外科 (2004) 57, 95-96
  
• 伊達洋至、清水信義： 移植医療の実際−薬剤選択を中心に、肺移植． 月刊薬事 (2004) 46, 1787-1791
  
• 伊達洋至、青江　基、佐野由文、清水信義： 肺移植． 現代医療 (2004) 36, 79-84
  
• 伊達洋至： 肺気腫に対する外科治療−LVRSと肺移植−． 呼吸器ケア (2004) 2, 650-655
  
• 小笠原豊, 土井原博義, 青江基, 清水信義： 甲状腺癌遠隔転移巣に対する手術施行例の検討． 内分泌外科 (2004) 21, 273-277
  
• 平成人, 太田徹哉, 村上正和, 土井原博義, 清水信義： 食道癌術後,急速な心不全症状を呈した心臓転移の1剖検例 手術 (2004) 58, 2177-2180
  
• 伊達洋至、清水信義： 肺移植の適応と現況． 日本医師会雑誌 (2004) 131, 662-663
  
• 小笠原豊, 土井原博義, 清水信義： LigaSureTMを用いた内視鏡補助下甲状腺手術の経験． 日本内視鏡外科学会雑誌 (2004) 9, 693-696
  
• 内藤稔： NST活動の実際　回診とミーティング． 医薬ジャーナル (2004) 40, 220-226
  
• 安藤陽夫, 清水信義： 肺癌に対する胸腔鏡下手術の現状と展望． 外科 (2004) 66, 401-405
  
• 北村泰博, 清水信義, 青江基, 伊達洋至, 永広格, 安藤陽夫： 凍結保存気管移植における長期保存の検討． 日本呼吸器外科学会雑誌 (2004) 18, 93-97
  

和文著作

症例報告

• 杉本誠一郎，永廣 格，青江 基，清水信義： 胸壁切除術にて診断の確定した甲状腺乳頭癌肋骨転移の1例． 日本呼吸器外科学会雑誌 (2004) 18, 751-754
  
• 杉本誠一郎，土井原博義，高橋寛敏，小笠原　豊，清水信義： 乳房温存療法後に発症したBOOP様肺炎の3例． 乳癌の臨床 (2004) 19, 385-390
  
• 冨山浩司, 越宗龍一郎, 土井原博義, 清水信義, 大原信哉： 長期にわたり再発を繰り返している副甲状腺癌の1例 癌の臨床 (2004) 49, 1647-1650
  
• 太田徹哉，平井隆二，清水信義： 腹腔動脈起始部閉塞を伴う膵管内乳頭腺癌に対して前後膵十二指腸動脈温存PPPDを施行しえた１例． 手術 (2004) 58, 127-130
  
• 藤田武郎, 大村泰之,高尾智也, 西英行, 福田和馬, 間野正之, 小松原正吉, 土井原博義, 清水信義, 田口孝爾： 横隔膜腹腔側に発生した悪性solitary fibrous tumorの1例． 日本消化器外科学会雑誌 (2004) 37, 1571-1576
  
• 徳毛誠樹, 永廣格, 杉本誠一郎, 田尾裕之, 源寛二, 清水信義： 肺癌術後気管支断端瘻に対してフィブリン糊の粘膜下注入で閉鎖し得た1例． 日本呼吸器外科学会雑誌 (2004) 18, 716-720
  
• 木村英夫, 松原広己, 宮地晃平, 河野康之, 伴場主一, 藤尾栄起, 宮地克維, 中村一文, 森田宏, 斉藤博則, 江森哲郎, 五藤恵次, 伊達洋至, 清水信義, 大江透： フローランによる薬剤性間質性肺炎をきたした原発性肺高血圧症の1例． Progress in Medicine (2004) 24, 294-298
  
• 大平洋, 辻野一三, 池田大輔, 神垣光徳, 石丸信司, 坂上慎二, 西村正治, 伊達洋至, 佐野由文, 清水信義： 原発性肺高血圧症に伴う蛋白漏出性胃腸症が生体肺移植後に軽快した1例． Therapeutic Research (2004) 25, 1999-2001
  
• 杉本誠一郎, 土井原博義, 小笠原豊, 清水信義, 濱崎周次： 長期追跡中(25年),リンパ節・骨転移再発治癒後に発症した乳癌肝転移の1例． 乳癌の臨床 (2004) 19, 501-504
  
• 浅野博昭, 村上正和, 佃和憲, 内藤稔, 清水信義： 術前放射線化学療法が有用であった進行下部直腸癌の1切除例． 手術 (2004) 58, 2073-2076