脳神経制御学 ・ 教授 阿部康二 Deguchi K, Tsuru K, Hayashi T, Takaishi M, Nagahara M, Nagotani S, Sehara Y, Jin G, Zhang H, Hayakawa S, Shoji M, Miyazaki M, Osaka A, Huh NH and Abe K.: Implantation of a new porous gelatin-siloxane hybrid into a brain lesion as a potential scaffold for tissue regeneration. J.Cereb.Blood Flow Metab. (2006) 26, 1263-1273. Hayashi T, Deguchi K, Nagotani S, Zhang H, Sehara Y, Tsuchiya A, and Abe K. : Cerebral ischemia and angiogenesis. Curr.Neurovasc.Res. (2006) 3, 119-129. Hayashi T, Syoji M, and Abe K.: Molecular mechanisms of ischemic neuronal cell death--with relevance to Alzheimer's disease. Curr.Alzheimer Res. (2006) 3, 351-358. Hayashi T, Kamada H, Jin G, Deguchi K, Nagotani S, Sehara Y, Zhang H, Nagano I, Shoji M, and Abe K.: Different expression of low density lipoprotein receptor and ApoE between young adult and old rat brains after ischemia. Neurol.Res. (2006) 28, 822-825. Iwai M, Ikeda T, Hayashi T, Sato K, Nagata T, Nagano I, Shoji M, Ikenoue T, and Abe K.: Temporal profile of neural stem cell Proliferation in the subventricular zone after ischemia/hypoxia in the neonatal rat brain. Neurol.Res. (2006) 28, 461-468. Murakami T, Paitel E, Kawarabayashi T, Ikeda M, Chishti MA, Janus C, Matsubara E, Sasaki A, Kawarai T, Phinney AL, Harigaya Y, Horne P, Egashira N, Mishima K, Hanna A, Yang J, Iwasaki K, Takahashi M, Fujiwara M, Ishiguro K, Bergeron C, Carlson GA, Abe K, Westaway D, St George-Hyslop P, and Shoji M.: Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration,memory disturbance,and phenotypic variation. Am.J.Pathol. (2006) 169, 1365-1375. Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, and Abe K.: Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene. J.Neurosci.Res. (2006) 84, 980-992. Ono Y, Manabe Y, Sakai K, Hayashi Y, and Abe K.: Clonic perseveration in the subacute stage of Japanese encephalitis. J.Neurol.Sci. (2006) 251, 107-109. Samura E, Shoji M, Kawarabayashi T, Sasaki A, Matsubara E, Murakami T, Wuhua X, Tamura S, Ikeda M, Ishiguro K, Saido TC, Westaway D, St George Hyslop P, Harigaya Y, and Abe K.: Enhanced accumulation of tau in doubly transgenic mice expressing mutant betaAPP and presenilin-1. Brain Res. (2006) 1094, 192-199. Sasaki S, Warita H, Komori T, Murakami T, Abe K, and Iwata M.: Parvalbumin and calbindin D-28k immunoreactivity in transgenic mice with a G93A mutant SOD1 gene. Brain Res. (2006) 1083, 196-203. Sehara Y, Hayashi T, Deguchi K, Nagotani S, Zhang H, Shoji M, and Abe K.: Distribution of inducible mitric oxide synthase and cell proliferation in rat brain after transient middle cerebral artery occlusion. Brain Res. (2006) 1093, 190-197. Yamashita T, Ninomiya M, Hernandez Acosta P, Garcia-Verdugo JM, Sunabori T, Sakaguchi M, Adachi K, Kojima T, Hirota Y, Kawase T, Araki N, Abe K, Lkano H, and Sawamoto K.: Subventricular zone-derived neuroblasts migrate and differentiate into mature neurons in the post-stroke adult striatum. J.Neurosci. (2006) 26, 6627-6636. Yamashita T, Deguchi K, Sawamoto K, Okano H, Kamiya T, and Abe K.: Neuroprotection and Neurosupplementation in Ischemic Brain. Biochem.Soc.Trans. (2006) 34, 1310-1312. Zhang H, Hayashi T, Tsuru K, Deguchi K, Nagahara M, Hayakawa S, Nagai M, Kamiya T, Osaka A, and Abe K.: Vascular endothelial growth factor promotes brain tissue regeneration with a novel biomaterial polydimethylsiloxane-tetraethoxysilane. Brain Res. (2006) 1132, 29-35. 阿部康二、永野功: ALSに対するIGF-1脊髄腔内持続注入療法 難病と在宅ケア (2006) 11, 60-63. 阿部康二: 急性期血栓溶解療法の基礎病態と治療適応 メビオ (2006) 23, 27-36. 阿部康二: 脳卒中の遺伝子治療 臨床リハビリテーション (2006) 15, 140-145. 阿部康二: 脳卒中の遺伝子治療 臨床リハ雑誌 (2006) 15, 140-145. 阿部康二: 脊髄性筋萎縮症 神経疾患：最新の治療 (2006) 2006-2008, 193-194. 阿部康二: 筋萎縮性側索硬化症：病態解明と治療法開発の進展 実験医学 (2006) 24, 869-874. 阿部康二: ALSの再生医療 作業療法ジャーナル (2006) 40, 464-472. 阿部康二: 神経内科診断の実際と神経機能検査法 言語聴覚士のための基礎知識：臨床神経学・高次機能障害学 (2006) 40-48. 阿部康二　: 生活習慣病によるAlzheimer病予防のエビデンス メビオ (2006) 23, 110-119. 阿部康二: フリーラジカルと脳卒中治療 別冊医学のあゆみ「脳卒中〜基礎研究と臨床の最前線〜」 (2006) 5-10. 阿部康二: 脳梗塞に対する再生医療 循環器科 (2006) 59, 488-495. 阿部康二: 筋萎縮性側索硬化症 クリニカル・ニューロサイエンス「ミトコンドリア異常とその他の疾患」 (2006) 24, 694-695. 阿部康二: ALSの再生医療再生医療 作業療法ジャーナル (2006) 40, 464-472. 阿部康二: 酸化ストレスと脳梗塞 医学のあゆみ (2006) 218, 96-102. 阿部康二: IGF-１とALS 細胞増殖因子と再生医療 (2006) 358-363. 阿部康二: 脳循環代謝研究の変遷と今後への期待〜まだ見ぬ若い花のような人たちへの手紙〜 脳循環代謝 (2006) 18, 62-72. 座談会（内山真一郎、松本昌泰、阿部康二、塩川芳昭、鈴木倫保、片山泰朗）: 脳卒中の予防と治療における新しいコンセプトとモダリティー 分子脳血管病 (2006) 5, 1-12. 出口健太郎、阿部康二: 多孔性セラチンハイブリッドを用いた脳損傷再生医療 分子脳血管病 (2006) 5, 61-66. 成冨博章、阿部康二（対談）: 脳梗塞慢性期患者の管理と治療 総合臨床 (2006) 55, 2117-2124. 脳神経制御学 ・ 助教授 神谷達司 Suda S, Komaba Y, Kumagai T, Yamazaki M, Katsumata T, Kamiya T, and Katayama Y.: Progression of the olivopontocerebellar form of adrenoleukodystrophy as shown by MRI. Neurology (2006) 66, 144-145. Yamashita T, Deguchi K, Sawamoto K, Okano H, Kamiya T, and Abe K.: Neuroprotection and Neurosupplementation in Ischemic Brain. Biochem.Soc.Trans. (2006) 34, 1310-1312. Zhang H, Hayashi T, Tsuru K, Deguchi K, Nagahara M, Hayakawa S, Nagai M, Kamiya T, Osaka A, and Abe K.: Vascular endothelial growth factor promotes brain tissue regeneration with a novel biomaterial polydimethylsiloxane-tetraethoxysilane. Brain Res. (2006) 1132, 29-35. 加藤健吾、島崎久仁子、神谷達司、横田英典、宮脇貴裕、小黒恵司、上田雅之、雨宮志門、西山康裕、須田智、渡辺英寿、岡部勝、菅野龍彦、片山泰朗: RAT局所脳虚血モデルにおける骨髄間葉系幹細胞の投与方法による分布と脳保護効果 脳卒中 (2006) 28, 607-611. 片山泰朗、桂研一郎、神谷達司、五十嵐博中、大久保誠二: 脳梗塞急性期の脳保護療法ー基礎および臨床の面からー 分子脳血管病 (2006) 5, 131-134. 神谷達司: 実験的脳虚血におけるFK506の有効性に関する系統的再検討とメタアナリシス 分子脳血管病 (2006) 5, 96-101. 脳神経制御学 ・ 助手 林健 Deguchi K, Tsuru K, Hayashi T, Takaishi M, Nagahara M, Nagotani S, Sehara Y, Jin G, Zhang H, Hayakawa S, Shoji M, Miyazaki M, Osaka A, Huh NH and Abe K.: Implantation of a new porous gelatin-siloxane hybrid into a brain lesion as a potential scaffold for tissue regeneration. J.Cereb.Blood Flow Metab. (2006) 26, 1263-1273. Hayashi T, Deguchi K, Nagotani S, Zhang H, Sehara Y, Tsuchiya A, and Abe K. : Cerebral ischemia and angiogenesis. Curr.Neurovasc.Res. (2006) 3, 119-129. Hayashi T, Syoji M, and Abe K.: Molecular mechanisms of ischemic neuronal cell death--with relevance to Alzheimer's disease. Curr.Alzheimer Res. (2006) 3, 351-358. Hayashi T, Kamada H, Jin G, Deguchi K, Nagotani S, Sehara Y, Zhang H, Nagano I, Shoji M, and Abe K.: Different expression of low density lipoprotein receptor and ApoE between young adult and old rat brains after ischemia. Neurol.Res. (2006) 28, 822-825. Iwai M, Ikeda T, Hayashi T, Sato K, Nagata T, Nagano I, Shoji M, Ikenoue T, and Abe K.: Temporal profile of neural stem cell Proliferation in the subventricular zone after ischemia/hypoxia in the neonatal rat brain. Neurol.Res. (2006) 28, 461-468. Saito A, Hayashi T, Okuno S, Nishi T, and Chan PH.: Modulation of prolene-rich akt substrate survival signaling pathways by oxidative stress in mouse brains after transient focal cerebral ischemia. Stroke (2006) 37, 513-517. Sehara Y, Hayashi T, Deguchi K, Nagotani S, Zhang H, Shoji M, and Abe K.: Distribution of inducible mitric oxide synthase and cell proliferation in rat brain after transient middle cerebral artery occlusion. Brain Res. (2006) 1093, 190-197. Zhang H, Hayashi T, Tsuru K, Deguchi K, Nagahara M, Hayakawa S, Nagai M, Kamiya T, Osaka A, and Abe K.: Vascular endothelial growth factor promotes brain tissue regeneration with a novel biomaterial polydimethylsiloxane-tetraethoxysilane. Brain Res. (2006) 1132, 29-35. 脳神経制御学 ・ 助手 瓦林毅 Harigaya Y, Tomidokoro Y, Ikeda M, Sasaki A, Kawarabayashi T, Matsubara E, Kanai M, Saito TC, Younkin SG, and Shoji M.: Type-specific ebolution of amyloid plaque and angiopathy in APPsw mice. Neurosci.Lett. (2006) 395, 37-41. Murakami T, Paitel E, Kawarabayashi T, Ikeda M, Chishti MA, Janus C, Matsubara E, Sasaki A, Kawarai T, Phinney AL, Harigaya Y, Horne P, Egashira N, Mishima K, Hanna A, Yang J, Iwasaki K, Takahashi M, Fujiwara M, Ishiguro K, Bergeron C, Carlson GA, Abe K, Westaway D, St George-Hyslop P, and Shoji M.: Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration,memory disturbance,and phenotypic variation. Am.J.Pathol. (2006) 169, 1365-1375. 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(2006) 1083, 196-203. 脳神経制御学 ・ 助手 永井真貴子 Kikuchi H, Almer G, Yamashita S, Guegan C, Nagai M, Xu Z, Sosunov AA, McKhann GM 2nd, and Przedborski S.: Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model. Proc.Natl.Acad.Sci.U.S.A. (2006) 103, 6025-6030. Koyama S, Arakawa S, Chang-Hong R, Wada M, Kawanami T, Krita K, Kato M, Nagai M, Aoki M, Itoyama Y, Sobue G, Chan PH, and Kato T.: Alteration of familial ALS-linked mutant SOD1 solubility with disease progression:its modulation by the proteasome and Hsp70. Biochem.Biophys.Res.Commun. (2006) 343, 719-730. Matsumoto A, Okada Y, Nakamichi M, Nakamura M, Toyama Y, Sobue G, Nagai M, Aoki M, Itoyama Y, and Okano H.: Disease progression of human SOD1(G93A)transgenic ALS model rats. J.Neurosci.Res. (2006) 83, 119-133. Nagai M, Kikuchi H and Przedborski S.: Experimental Models of Motor Neuron Disease.Amyotrophic Lateral Sclerosis.ed by Mitsumoto H,Przedborski S,Gordon PH. Taylor & Francis Group; New York (2006) 525-550. Ohta Y, Nagai M, Nagata T, Murakami T, Nagano I, Narai H, Kurata T, Shiote M, Shoji M, and Abe K.: Intrathecal injection of epidermal growth factor and fibroblast growth factor 2 promotes proliferation of neural precursor cells in the spinal cords of mice with mutant human SOD1 gene. J.Neurosci.Res. (2006) 84, 980-992. Wu DC, Re DB, Nagai M, Ischiropoulos H, and Prezedborski S.: The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Pro.Natl.Acad.Sci.U.S.A. (2006) 103, 12132-12137. Zhang H, Hayashi T, Tsuru K, Deguchi K, Nagahara M, Hayakawa S, Nagai M, Kamiya T, Osaka A, and Abe K.: Vascular endothelial growth factor promotes brain tissue regeneration with a novel biomaterial polydimethylsiloxane-tetraethoxysilane. Brain Res. (2006) 1132, 29-35. 永井真貴子: 幹細胞の発生分化と神経疾患への治療応用 分子脳血管病 (2006) 10, 3-8.