Summary: Nervous system, especially brain is the most complicated natural system in structure and function during natural evolution process. In recent years, zebrafish Danio rerio, nematoid Caenorhadits elegans and fruitfly Drosophila melanogaster have attracted more and more scientists' attention. The lower animals have become biological models in some of the major basic research, and they are also important models for neurobiology research. Long-term natural selection has formed the insect-specific neural signal processing and behavioral brain mechanisms. Compared with the vertebrate, it is more advantageous to solve some of the basic theory of neuroscience by using insect brain.
Since 1994, our laboratory began to develop the technique-CP embedding technique, we have successively applied it to immunohistochemistry and in situ hybridization, as well as the location of the target cells and genes. At present, this technology is applied for all insects, especially the smaller insects. The serotonin (5-hydroxytryptamine, 5-HT) is a monoaminergic neurotransmitter widely distributed throughout the central nervous systems of both vertebrates and invertebrates regulate the circadian rhythms, light-dark adaptation, defensive, growth, feeding behaviors. In invertebrates, 5-HT may act as a classical neurotransmitters, may also be used as a neuromodulator or neurohormone. As mammals, the inset also have two 5-HT systems regulate respectively the generation of the central and peripheral 5-HT.
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