資料   MIC Interpretive Standards  (CLSI, USA)  CLSI M7-A8, M100-S21
            2011
腸内細菌科(E.coli, Klebsiella, Enterobacter, Serratia など)  
  Antimicrobial Agent   MIC(μg/ml)Interpretive Standard Comments
    S I R
  Piperacillin PIPC ≦16 32〜64 ≧128  
  Ampicillin/sulbactam ABPC/SBT ≦8/4 16/8 ≧32/16  
  Cefazolin CEZ ≦2 4 ≧8 M100-S20より変更
  Cefmetazole CMZ ≦16 32 ≧64  
  Cefepime CFPM ≦8 16 ≧32 参考CZOP
  Cefoperazone CPZ ≦16 32 ≧64  
  Cefotaxime CTX ≦1 2 ≧4 M100-S20より変更
  Ceftazidime CAZ ≦4 8 ≧16  
  Cefdinir CFDN ≦1 2 ≧4  
  Imipenem IPM ≦1 2 ≧4 M100-S20より変更
  Meropenem MEPM ≦1 2 ≧4 M100-S20より変更
  Aztreonam AZT ≦4 8 ≧16 M100-S20より変更
  Gentamicin GM ≦4 8 ≧16  
  Amikacin AMK ≦16 32 ≧64  
  Levofloxacin LVFX ≦2 4 ≧8  
             
緑膿菌、ブドウ糖非発酵菌          
  Antimicrobial Agent   MIC(μg/ml)Interpretive Standard Comments
    S I R
  Piperacillin PIPC ≦64 - ≧128  緑膿菌
    ≦16 32〜64 ≧128  緑膿菌以外
  Piperacillin-tazobactam PIPC/TAZ ≦64/4 - ≧128/4  緑膿菌
    ≦16/4 32〜64/4 ≧128/4  緑膿菌以外
  Ceftazidime CAZ ≦8 16 ≧32  
  Cefepime CFPM ≦8 16 ≧32  
  Cefoperazone CPZ ≦16 32 ≧64  緑膿菌以外
  Imipenem IPM ≦4 8 ≧16  
  Meropenem MEPM ≦4 8 ≧16  
  Aztreonam AZT ≦8 16 ≧32  
  Gentamicin GM ≦4 8 ≧16  
  Amikacin AMK ≦16 32 ≧64  
  Minocycline MINO ≦4 8 ≧16  緑膿菌以外
  Ciprofloxacin CPFX ≦1 2 ≧4  
  Levofloxacin LVFX ≦2 4 ≧8  
             
Staphylococcus spp.(ブドウ球菌属)        
  Antimicrobial Agent   MIC(μg/ml)Interpretive Standard Comments
    S I R
  Oxacillin MPIPC ≦2 - ≧4 For S.aureus
    ≦0.25 - ≧0.5 For coagulase-negative staphylococci
  Ampicillin ABPC ≦0.25 - ≧0.5  
  Ampicillin/sulbactam ABPC/SBT ≦8/4 16/8 ≧32/16  
  Cefazolin CAZ ≦8 16 ≧32  
  Cefmetazole CMZ ≦8 16 ≧32  
  Imipenem IPM ≦4 8 ≧16  
  Gentamicin GM ≦4 8 ≧16  
  Clarithromycin CAM ≦2 4 ≧8  
  Minocycline MINO ≦4 8 ≧16  
  Levofloxacin LVFX ≦1 2 ≧4 M100-S20より変更
  Vancomycin VCM ≦4 8〜16 ≧32  
  Teicoplanin TEIC ≦8 16 ≧32  
  Clindamycin CLDM ≦0.5 1〜2 ≧4  
  Linezolid LZD ≦4 - ≧8  
             
Enterococcus spp.(腸球菌属)        
  Antimicrobial Agent   MIC(μg/ml)Interpretive Standard Comments
    S I R
  Ampicillin ABPC ≦8 - ≧16  
  Vancomycin VCM ≦4 8〜16 ≧32  
  Teicoplanin TEIC ≦8 16 ≧32  
  Minocycline MINO ≦4 8 ≧16  
  Levofloxacin LVFX ≦2 4 ≧8  
  Linezolid LZD ≦2 4 ≧8  
             
Haemophilus spp.(ヘモフィルス属)        
  Antimicrobial Agent   MIC(μg/ml)Interpretive Standard Comments
    S I R
  Ampicillin ABPC ≦1 2 ≧4  
  Ampicillin/sulbactam ABPC/SBT ≦2/1 - ≧4/2  
  Cefotaxime CTX ≦2 - - (参考CZOP)
  Cefdinir CFDN ≦1 - -  
  Meropenem MEPM ≦0.5 - - 耐性菌まれ
  Imipenem IPM ≦4 - -  
  Clarithromycin CAM ≦8 16 ≧32  
  Levofloxacin LVFX ≦2 - - 耐性菌まれ
  Tetracycline TC ≦2 4 ≧8 (MINO参考)
             
Streptococcus pneumoniae(肺炎球菌)        
  Antimicrobial Agent   MIC(μg/ml)Interpretive Standard Comments
    S I R
  Penicillin PCG ≦2 4 ≧8 非髄膜炎
    ≦0.06 - ≧0.12 髄膜炎
  Cefotaxime CTX ≦1 2 ≧4 非髄膜炎
  ≦0.5 1 ≧2 髄膜炎
  Cefdinir CFDN ≦0.5 1 ≧2  
  Meropenem MEPM ≦0.25 0.5 ≧1  
  Imipenem IPM ≦0.12 0.25〜0.5 ≧1  
  Clarithromycin CAM ≦0.25 0.5 ≧1  
  Levofloxacin LVFX ≦2 4 ≧8  
  Clindamycin CLDM ≦0.25 0.5 ≧1  
  Tetracycline TC ≦1 2 ≧4 (MINO参考)
             
Streptococcus spp.(肺炎球菌以外の連鎖球菌属)      
  Antimicrobial Agent   MIC(μg/ml)Interpretive Standard Comments
    S I R
  Penicillin PCG ≦0.12 0.25〜2 ≧4  
  Ampicillin ABPC ≦0.25 0.5〜4 ≧8  
  Cefotaxime CTX ≦1 2 ≧4  
      ≦0.5     β溶連菌のみ
  Meropenem MEPM ≦0.5 - -  
  Clarithromycin CAM ≦0.25 0.5 ≧1  
  Levofloxacin LVFX ≦2 4 ≧8  
  Clindamycin CLDM ≦0.25 0.5 ≧1  
  Tetracycline TC ≦2 4 ≧8 (MINO参考)
             
Neisseria gonorrhoeae(淋菌)        
  Antimicrobial Agent   MIC(μg/ml)Interpretive Standard Comments
    S I R
  Penicillin PCG ≦0.06 0.12〜0.25 ≧0.5  
  Ampicillin ABPC ≦0.12 0.25〜1 ≧2  
  Cefotaxime CTX ≦0.12 - - 耐性菌まれ
  Meropenem MEPM ≦0.25 - - 耐性菌まれ
  Minocycline MINO ≦2 - - 耐性菌まれ
  Levofloxacin LVFX ≦0.03 0.06 ≧0.12 ほぼ耐性

 

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