資料 | MIC Interpretive Standards (CLSI, USA) | CLSI M7-A8, M100-S21 | ||||
2011 | ||||||
腸内細菌科(E.coli, Klebsiella, Enterobacter, Serratia など) | ||||||
Antimicrobial Agent | MIC(μg/ml)Interpretive Standard | Comments | ||||
S | I | R | ||||
Piperacillin | PIPC | ≦16 | 32〜64 | ≧128 | ||
Ampicillin/sulbactam | ABPC/SBT | ≦8/4 | 16/8 | ≧32/16 | ||
Cefazolin | CEZ | ≦2 | 4 | ≧8 | M100-S20より変更 | |
Cefmetazole | CMZ | ≦16 | 32 | ≧64 | ||
Cefepime | CFPM | ≦8 | 16 | ≧32 | 参考CZOP | |
Cefoperazone | CPZ | ≦16 | 32 | ≧64 | ||
Cefotaxime | CTX | ≦1 | 2 | ≧4 | M100-S20より変更 | |
Ceftazidime | CAZ | ≦4 | 8 | ≧16 | ||
Cefdinir | CFDN | ≦1 | 2 | ≧4 | ||
Imipenem | IPM | ≦1 | 2 | ≧4 | M100-S20より変更 | |
Meropenem | MEPM | ≦1 | 2 | ≧4 | M100-S20より変更 | |
Aztreonam | AZT | ≦4 | 8 | ≧16 | M100-S20より変更 | |
Gentamicin | GM | ≦4 | 8 | ≧16 | ||
Amikacin | AMK | ≦16 | 32 | ≧64 | ||
Levofloxacin | LVFX | ≦2 | 4 | ≧8 | ||
緑膿菌、ブドウ糖非発酵菌 | ||||||
Antimicrobial Agent | MIC(μg/ml)Interpretive Standard | Comments | ||||
S | I | R | ||||
Piperacillin | PIPC | ≦64 | - | ≧128 | 緑膿菌 | |
≦16 | 32〜64 | ≧128 | 緑膿菌以外 | |||
Piperacillin-tazobactam | PIPC/TAZ | ≦64/4 | - | ≧128/4 | 緑膿菌 | |
≦16/4 | 32〜64/4 | ≧128/4 | 緑膿菌以外 | |||
Ceftazidime | CAZ | ≦8 | 16 | ≧32 | ||
Cefepime | CFPM | ≦8 | 16 | ≧32 | ||
Cefoperazone | CPZ | ≦16 | 32 | ≧64 | 緑膿菌以外 | |
Imipenem | IPM | ≦4 | 8 | ≧16 | ||
Meropenem | MEPM | ≦4 | 8 | ≧16 | ||
Aztreonam | AZT | ≦8 | 16 | ≧32 | ||
Gentamicin | GM | ≦4 | 8 | ≧16 | ||
Amikacin | AMK | ≦16 | 32 | ≧64 | ||
Minocycline | MINO | ≦4 | 8 | ≧16 | 緑膿菌以外 | |
Ciprofloxacin | CPFX | ≦1 | 2 | ≧4 | ||
Levofloxacin | LVFX | ≦2 | 4 | ≧8 | ||
Staphylococcus spp.(ブドウ球菌属) | ||||||
Antimicrobial Agent | MIC(μg/ml)Interpretive Standard | Comments | ||||
S | I | R | ||||
Oxacillin | MPIPC | ≦2 | - | ≧4 | For S.aureus | |
≦0.25 | - | ≧0.5 | For coagulase-negative staphylococci | |||
Ampicillin | ABPC | ≦0.25 | - | ≧0.5 | ||
Ampicillin/sulbactam | ABPC/SBT | ≦8/4 | 16/8 | ≧32/16 | ||
Cefazolin | CAZ | ≦8 | 16 | ≧32 | ||
Cefmetazole | CMZ | ≦8 | 16 | ≧32 | ||
Imipenem | IPM | ≦4 | 8 | ≧16 | ||
Gentamicin | GM | ≦4 | 8 | ≧16 | ||
Clarithromycin | CAM | ≦2 | 4 | ≧8 | ||
Minocycline | MINO | ≦4 | 8 | ≧16 | ||
Levofloxacin | LVFX | ≦1 | 2 | ≧4 | M100-S20より変更 | |
Vancomycin | VCM | ≦4 | 8〜16 | ≧32 | ||
Teicoplanin | TEIC | ≦8 | 16 | ≧32 | ||
Clindamycin | CLDM | ≦0.5 | 1〜2 | ≧4 | ||
Linezolid | LZD | ≦4 | - | ≧8 | ||
Enterococcus spp.(腸球菌属) | ||||||
Antimicrobial Agent | MIC(μg/ml)Interpretive Standard | Comments | ||||
S | I | R | ||||
Ampicillin | ABPC | ≦8 | - | ≧16 | ||
Vancomycin | VCM | ≦4 | 8〜16 | ≧32 | ||
Teicoplanin | TEIC | ≦8 | 16 | ≧32 | ||
Minocycline | MINO | ≦4 | 8 | ≧16 | ||
Levofloxacin | LVFX | ≦2 | 4 | ≧8 | ||
Linezolid | LZD | ≦2 | 4 | ≧8 | ||
Haemophilus spp.(ヘモフィルス属) | ||||||
Antimicrobial Agent | MIC(μg/ml)Interpretive Standard | Comments | ||||
S | I | R | ||||
Ampicillin | ABPC | ≦1 | 2 | ≧4 | ||
Ampicillin/sulbactam | ABPC/SBT | ≦2/1 | - | ≧4/2 | ||
Cefotaxime | CTX | ≦2 | - | - | (参考CZOP) | |
Cefdinir | CFDN | ≦1 | - | - | ||
Meropenem | MEPM | ≦0.5 | - | - | 耐性菌まれ | |
Imipenem | IPM | ≦4 | - | - | ||
Clarithromycin | CAM | ≦8 | 16 | ≧32 | ||
Levofloxacin | LVFX | ≦2 | - | - | 耐性菌まれ | |
Tetracycline | TC | ≦2 | 4 | ≧8 | (MINO参考) | |
Streptococcus pneumoniae(肺炎球菌) | ||||||
Antimicrobial Agent | MIC(μg/ml)Interpretive Standard | Comments | ||||
S | I | R | ||||
Penicillin | PCG | ≦2 | 4 | ≧8 | 非髄膜炎 | |
≦0.06 | - | ≧0.12 | 髄膜炎 | |||
Cefotaxime | CTX | ≦1 | 2 | ≧4 | 非髄膜炎 | |
≦0.5 | 1 | ≧2 | 髄膜炎 | |||
Cefdinir | CFDN | ≦0.5 | 1 | ≧2 | ||
Meropenem | MEPM | ≦0.25 | 0.5 | ≧1 | ||
Imipenem | IPM | ≦0.12 | 0.25〜0.5 | ≧1 | ||
Clarithromycin | CAM | ≦0.25 | 0.5 | ≧1 | ||
Levofloxacin | LVFX | ≦2 | 4 | ≧8 | ||
Clindamycin | CLDM | ≦0.25 | 0.5 | ≧1 | ||
Tetracycline | TC | ≦1 | 2 | ≧4 | (MINO参考) | |
Streptococcus spp.(肺炎球菌以外の連鎖球菌属) | ||||||
Antimicrobial Agent | MIC(μg/ml)Interpretive Standard | Comments | ||||
S | I | R | ||||
Penicillin | PCG | ≦0.12 | 0.25〜2 | ≧4 | ||
Ampicillin | ABPC | ≦0.25 | 0.5〜4 | ≧8 | ||
Cefotaxime | CTX | ≦1 | 2 | ≧4 | ||
≦0.5 | β溶連菌のみ | |||||
Meropenem | MEPM | ≦0.5 | - | - | ||
Clarithromycin | CAM | ≦0.25 | 0.5 | ≧1 | ||
Levofloxacin | LVFX | ≦2 | 4 | ≧8 | ||
Clindamycin | CLDM | ≦0.25 | 0.5 | ≧1 | ||
Tetracycline | TC | ≦2 | 4 | ≧8 | (MINO参考) | |
Neisseria gonorrhoeae(淋菌) | ||||||
Antimicrobial Agent | MIC(μg/ml)Interpretive Standard | Comments | ||||
S | I | R | ||||
Penicillin | PCG | ≦0.06 | 0.12〜0.25 | ≧0.5 | ||
Ampicillin | ABPC | ≦0.12 | 0.25〜1 | ≧2 | ||
Cefotaxime | CTX | ≦0.12 | - | - | 耐性菌まれ | |
Meropenem | MEPM | ≦0.25 | - | - | 耐性菌まれ | |
Minocycline | MINO | ≦2 | - | - | 耐性菌まれ | |
Levofloxacin | LVFX | ≦0.03 | 0.06 | ≧0.12 | ほぼ耐性 |