原　著

 1)Zhu, J., Pan, H.O., Suzuki, F. and Takigawa, M.: Proto-oncogene expression in ahuman chondrosarcoma cell line: HCS-2/8. Jpn. J. Cancer Res., 85, 364-371,1994.

 2)Farres, J., Wang, X., Takahashi K., Cunningham S.J., Wang T.T and Weiner H.:Effects of changing glutamate 487 to lysine in rat and human livermitochondrial aldehyde dehydrogenase. J. Biol. Chem., 269, 13854-13860, 1994.

 3)Iwamoto, M., Jikko, A., Murakami, H., Shimazu, A., Nakashima, K., Iwamoto, M.,Takigawa, M., Baba, H., Suzuki, F. and Kato, Y.: Changes in parathyroid hormonereceptors during chondrocyte cytodifferentiation. J. Biol. Chem., 269,17245-17251, 1994.

 4)Tuckwell, D.S., Ayad, S., Grant, M.E., Takigawa, M. and Humphries M.J.:Conformation dependence of integrin-type・ collagen binding. J. Cell Science, 107, 993-1005, 1994.

 5)Kishino, A., Nakayama, C., Nakanishi, T., Fukushima , N., Irie, T. and Noguchi,H.: Monoclonal antibodies raised against rat hippocampal homogenate and thecharacterization of antigens. Hybridoma, 13, 311-316, 1994.

 6)Nakanishi, T., Takahashi, K., Aoki, C., Nishikawa, K., Hattori, T. andTaniguchi, S.: Expression of nerve growth factor family neurotrophins in amouse osteoblastic cell line. Biochem. Biophys. Res. Commun., 198, 891-897,1994.

 7)Nakanishi, T., Ohyama, K., Aoki, C., Kudo, A., Hattori, T., Takahashi, K.,Taniguchi, S. and Takigawa, M.: Expression of trkC in a mouse osteoblastic cellline and its response to neurotrophin-3. Biochem. Biophys. Res. Commun., 203,1268-1274, 1994.

 8)Takahashi, K., Hattori, T., Nakanishi, T., Nohno, T., Fujita, N., Ishihama, A.and Taniguchi, S.: Repression of in vitro transcription of the Escherichia colifnr and narX genes by FNR protein. FEBS Lett., 340, 59-64, 1994.

 9)Nishikawa, K., Nakanishi, T., Aoki, C., Hattori, T., Takahashi, K. andTaniguchi, S.: Differntial Expression of Homeobox-containing Genes Msx-1 andMsx-2 and Homeoprotein Msx-2 Expression during Chick Craniofacial Development.Biochem. Mol. Biol.International, 32, 763-771, 1994.

10) Ohuchi, H., Koyama, E., Myokai, F.,Nohno, T., Shiraga, F., Matsuo, T., Matsuo, N., Taniguchi, S. and Noji, S.:Expression patterns of two fibroblast growth factor receptor genes during earlychick eye development.  Experimental EyeResearch, 58, 649-658, 1994.

11) Takashiba, S., Noji, S., Nishimura, F.,Oyama, H., Kurihara, H., Nomura, Y., Taniguchi, S. and Murayama, Y.: Uniqueintronic variations of HLA-DQβ gene in early-onset periodontitis. J. Periodontol.., 65, 379-386,1994.

12) Matsuura, H., Myokai, F., Arata, J.,Noji, S. and Taniguchi, S.: Expression of type・transforming growth factor-β receptor mRNA in humanskin, as revealed by in situ hybridization. J. Dermatol. Sci., 8, 25-32, 1994.

13) Hisa, T., Hamada, T., Hirachi, Y.,Yoshioka, M., Takigawa, M. and Shigenaga, Y.: Senile lip licking.  Dermatology, 191, 339-340, 1995.

14) Hisa, T., Mochida, K., Taniguchi, S.,Goto, Y., Hamada, T., Yoshioka, M., Shigenaga, Y. and Takigawa, M.: Contactdermatitis from carboxy vinylpolymer. Contact Dermatitis, 33, 271, 1995.

15) Hisa, T., Taniguchi, S., Kobayashi, H.,Shigenaga, Y., Nomura, S. and Takigawa, M.: Apoptosis in normal skin. ActaDerm. Venereol., 75, 412-413, 1995.

16) Ohba, Y., Goto, Y., Kimura, Y., Suzuki,F., Hisa, T., Takahashi, K. and Takigawa, M.: Purification of an angiogenesisinhibitor from culture medium conditioned by a human chondrosarcoma-derivedchondrocytic cell line, HCS-2/8. Biochim. Biophys. Acta, 1245, 1-8, 1995.

17) Nakanishi, T., Ishii, K., Katayama, M.,Araki, W., Iwata, E. and Ogawa, N.: Characterization of neurotrophic factorsproduced by immortalized mouse brain glial cells (VR-2g). Biochem. Mol. Biol.Int., 36, 991-999, 1995.

18) Kinoshita, A., Tamura, T., Aoki, C.,Nakanishi, T., Sobue, S., Suzuki, F., Takahashi, K. and Takigawa, M.:Demonstration of endothelin (ET) receptors on cultured rabbit chondrocytes andstimulation of DNA synthesis and calcium influx by ET-1 via its receptors. CellBiol. Int., 19, 647-654, 1995.

19) 草野雅章、杉村正仁、滝川正春、鈴木不二男、野村賀寿雄、西村敬一、泊　清隆、坂井　勝也、篠田法正：生体内吸収性骨接合プレートとスクリューの開発に関する研究。第２報　生体内吸収性材料の基本特性。顎顔面バイオメカニクス学会誌、1、61-72、1995.

20) Asanuma, M., Kondo, Y., Nishibayashi,S., Iwata, E., Nakanishi, T. and Ogawa, N.: Age-related changes in compositionof transcription factor, AP-1 complex in the rat brain. Neurosci. Lett., 201,127-130, 1995.

21) Hisa, T., Ishii, M., Hirachi, Y., Onda,H., Mohri,I . and Takigawa, M.: Is atopic dermatitis related to the month ofbirth? Zeitschrift Dermatol., 181, 208-210, 1995. 

22) Matsuhashi, S., Noji, S., Koyama, E.,Myokai, F., Ohuchi, H, Taniguchi, S. and Hori, K.: A new gene, nel,encoding aMr.93 K protein with EGF-like repeats is strongly expressed in neural tissuesof early stage chick embryos., Develop. Dynamics, 203, 212-222, 1995.

23) 船山高明：ヒト扁平上皮癌におけるerbB関連遺伝子およびその遺伝子産物に関する研究。岡山歯学会雑誌、14、75-88、1995.

24) Ishizeki, K., Takigawa, M., Nawa, T.,Harada, Y. and Suzuki, F.: Meckel's cartilage chondrocytes in organ culturesynthesize bone-type proteins accompanying osteocytic phenotype expression.Anat. Embryol., 193, 61- 71, 1996.

25) Ishizeki, K., Takigawa, M., Nawa, T.and Suzuki, F.: Mouse Meckel's cartilage chondrocytes evoke bone-like matrixand further transform into osteocyte-like cells in culture. Anat. Res., 245,25-35, 1996.

26) Hattori, T., Takahashi, K., Nakanishi,T., Ohta, H., Fukui, K., Taniguchi, S. and Takigawa, M.: Novel FNR homologuesidentified in four representative oral facultative anaerobes: Capnocytophagaochracea, Capnocytophaga sputigena, Haemophilus aphrophilus, and Actinobacillusactino-mycetemcomitans. FEMS Microbiol. Lett., 137, 213-220, 1996.

27) Tsuji, M., Funahashi, S., Takigawa, M.,Seiki, M., Fujii, K. and Yoshida, T.: Expression of c-fos gene inhibitsproteoglycan synthesis in transfected chondrocyte. FEBS Lett., 381, 222-226,1996.

28) Iwata, E., Nakanishi, T., Ogawa, N.,Ohyama, K., Murakami, T. and Takigawa, M.: Neurotrophin-3 increases theDNA-binding activities of several transcription factors in a mouse osteoblasticcell line. Biochim. Biophys. Acta, 1311, 85-92, 1996.

29) Sakawa, A., Yutani, Y., Inui, K.,Shimizu, A., Yamano, Y., Kinoshita, A., Suzuki, F., Hattori, T. and Takigawa,M: Specific serum antibodies against membranous proteins of a human immortalchondrocytic cell line (HCS-2/8) in rheumatoid arthritis and their relation tothe natural history of the disease. J. Bone Miner. Metab., 14, 146-152, 1996.

30) Nakanishi, T., Ishii, K., Fukushima ,N., Asanuma, M., Iwta, E. and Ogawa, N.: Expression of mRNA encodingneurotrophic factors and its regulation in a hybrid neuronal cell line.Biochem. Mol. Biol. Int., 38, 763-772, 1996.

31) Tamura, T., Nakanishi, T., Kimura, Y.,Hattori, T., Sasaki, K., Norimatsu, H., Takahashi, K. and Takigawa,M.:Interleukin-1 induces Matrix degradation and release of basic fibroblastgrowth factor in clutured rabbit articular chondrocytes via nitric oxideproduction: A possible mechanism of pathological neovascularization inarthritis. Endocrinology, 137, 3729-3737, 1996.

32) Hisa, T., Taniguchi, S., Tsuruta, D.,Hirachi, Y., Ishizuka, S. and Takigawa, M.: Vitamin D inhibits endothelial cellmigration. Arch. Dermatol. Res., 288, 262-263, 1996.

33) Hisa, T., Taniguchi, S., Kakudo, K.,Ichihashi, M., Takashima, T., Kato, Y., Hayakawa, R. and Takigawa, M.:Establishment of an in vitro cell derived from human angiosarcoma. Bull Cancer,83, 589-591, 1996.

34)木村祐輔：ヒト軟骨肉腫由来クローン化軟骨細胞様細胞株における結合組織増殖因子の遺伝子発現とその機能解析。大阪大学歯学雑誌、41、29-55、1996.

35) Takahashi, K., Kubo, T., Kobayashi, K.,Imanishi, J., Takigawa, M., Arai, Y. and Hirasawa, Y.: Hydrostatic pressureinfluences mRNA expression of transforming growth factor-β1 and heat shock protein70 in chondrocyte-ike cell line. J. Orthopaedic Res., 15, 150-158, 1997.

36) Nakagawa, K., Sakiyama, H., Fukusawa,T., Matsumoto, M., Takigawa, M., Toyoguchi, T. and Moriya, H.: Coordinatechange between complement C1s production and chondrocyte differentiation invitro. Cell and Tissue Res., 289, 299-305, 1997.

37) Nakanishi, T., Kimura, Y., Tamura, T.,Ichikawa, H., Yamaai, Y., Sugimoto, T., and　Takigawa, M.: Cloning of a mRNApreferentially expressed in chondrocytes in differential display PCR from ahuman chondrocytic cell line that is identical with connective tissue growthfactor (CTGF) mRNA. Biochem. Biophys. Res. Commun., 234, 206-210, 1997.

38) Arai, Y., Kubo, T., Kobayashi, K.,Takeshita, K., Takahashi, K., Ikeda, T., manishi, J., Takigawa, M. andHirasawa, Y.: Adenovirus vector-mediated gene transduction to chondrocytes: Invitro evaluation of therapeutic efficacy of transforming growth factor-b1 andheat shock protein 70 gene transduction. J. Rheumatol., 24, 1787-1795, 1997.

39) Takigawa, M., Okawa, T., Pan H.-O.,Aoki, C., Takahashi, K., Zue J.-D. and Kinoshita, A.: Insulin-like growthfactors ・andII are autocrine factors in stimulating proteoglycan synthesis, a marker ofdifferentiated chondrocytes, acting through their respective receptors on aclonal human chondrosarcoma-derived chondrocyte cell line, HCS-2/8.Endocrinology, 138, 4390-4400, 1997.

40) 滝川正春、中西　徹、志茂　剛、西田　崇、大山和美：神経栄養因子の機能を介する骨粗鬆症の予防法の確立−培養骨芽細胞を用いた各種ビタミンの効果に関する基礎的検討−、Osteoporosis Japan、5、76-80、1997.

41) Davis , D., Tuckwell,D.S.,Calderwood,D.A., Weston , S.A. , Takigawa, M. and Humphries, M.J. : Molecular characterization of integrin-procollagenC-propeptide interactions. Eur. J. Biochem., 246, 274-282, 1997.

42) Ishida, O., Tanaka, Y., Morimoto, I.,Takigawa, M. and Eto, S.: Chondrocytes are regulated by cellular adhesionthough CD44 and hyaluronic acid pathway., J. Bone Miner. Res., 12, 1657-1663,1997.

43) Sasaki, K., Hattori, T., Fujisawa, T.,Takahashi, K., Inoue, H. and Takigawa, M.: Nitric oxide mediatesinterleukin-1-induced gene expression of matrix metalloproteinases and basicfibroblast growth factor in cultured rabbit articular chondrocytes. J.Biochem., 123, 431-439, 1998.

44) Hattori, T., Fujisawa, T., Sasaki, K.,Yutani, Y., Nakanishi, T., Takahashi, K. and Takigawa, M.:Isolation andcharacterization of a rheumatoid arthritis-specific antigen (RA-A47) from ahuman chondrocytic cell line (HCS-2/8). Biochem. Biophys. Res. Commun. 245,679-683, 1998.

45) Hisa, T., Kimura, Y., Takada, K.,Suzuki, F. and Takigawa, M.: Shikonin, an igredient of lithospermumerythrorhizon, inhibits angiogenesis in vivo and in vitro. Anticancer Res., 18,783-790, 1998.

46) Funayama, T., Nakanishi, T., Takahashi,K., Taniguchi, S., Takigawa, M. and Matsumura, T.: Overexpression of c-erbB-3in various stages of human squamous cell carcinoma. Oncology, 55, 161-167,1998.

47) Shimo, T., Nakanishi, T., Kimura, Y.,Nishida, T., Ishizeki, K., Matsumura, T. and Takigawa, M.: Inhibition ofendogenous expression of connective tissue growth factor by its antisenseoligonucleotide and antisense RNA suppresses proliferation and migration ofvascular　endothelialcells. J. Biochem., 124, 130-140, 1998.

48) Aoki, C., Nakanishi, T., Sogawa, N.,Ishii, K., Ogawa, N., Takigawa, M. and Furuta, H.: Stimulatory effects of4-methylcatechol, dopamine and levodopa on the expression of metallothionein-・(GIF) mRNA in immortalizedmouse brain glial cells (VR-2g).  BrainRes., 792, 335-339, 1998.

49) Fujimoto, W., Nakanishi, G., Hirakawa,S., Nakanishi, T., Shimo, T., Takigawa, M. and Arata, J.: Pachyonychiacongenita type 2: Keratin 17 mutation in a Japanese case. J. Am. Acad.Dermatol., 38, 1007-1009, 1998.

50) Nishida, T., Nakanishi, T., Shimo, T.,Asano, M., Hattori, T., Tamatani, T., Tezuka, K. and Takigawa, M.:Demonstration of receptors specific for connective tissue growth factor on ahuman chondrocytic cell line (HCS-2/8). Biochem. Biophys. Res. Commun., 247, 905-909, 1998.

51) Takahashi, K., Kubo, T., Arai, Y.,Kitajima, I., Takigawa, M., Imanishi, J. and Hirasawa, Y.: Hydrostatic pressureinduces expression of interleukin 6 and tumour necrosis factor α mRNAs in achondrocyte-like cell line. Ann. Rheum. Dis., 57, 231-236, 1998.

52) Uria, J. A., Balbin, M., Lopez,J. M.,Alvarez, J., Vizoso, F., Takigawa, M. and Lopez, O.C.: Collagenase-3 (MMP-13)expression in chondrosarcoma cells and its regulation by basic fibroblastgrowth factor. Am. J. Pathol., 153, 91-101, 1998.

53) Ishizeki, K., Nomura, S., Takigawa, M.,Shioji, H. and Nawa, T.: Expression of osteopontin in Meckel's cartilage cellsduring phenotypic transdifferentiation in vitro, as detected by in situhybridization and immunocytochemical analysis. Histochem. Cell Biol., 110,457-466, 1998.

54) Ikeda, T., Kubo, T., Arai, Y.,Nakanishi, T., Kobayashi, K., Takahashi, K., Imanishi, J., Takigawa, M. andHirasawa, Y.: Adenovirus-mediated gene delivery to the joints of guinea pigs.J. Rheum., 25, 1666-1673, 1998.

55) Maeda, S., Miyawaki, T., Nakanishi, T.,Takigawa, M. and Shimada, M.: Peripheral type benzodiazepine receptor in Tlymphocyte rich preparation. Life Sciences, 63, 1423-1430, 1998.

56) Tamatani, T., Kobayashi, H., Tezuka,K., Sakamoto, S., Suzuki, K., Nakanishi, T., Takigawa, M. and Miyano, T.:Establishment of the enzyme-linked immunosorbent assay for connective tissuegrowth factor (CTGF) and its detection in the sera of biliary atresia.  Biochem. Biophys. Res. Commun., 251, 748-752,1998.

57) Ohnishi, H., Oka, T., Kusachi, S.,Nakanishi, T., Takeda, K., Nakahama, M., Doi, M., Murakami, T., Ninomiya, Y.,Takigawa, M. and Tsuji, T.: Increased expression of connective tissue growthfactor in the infarct zone of experimentally induced myocardial infarction inrats. J. Mol. Cell Cardiol. 30, 2411-2422, 1998.

58) 志茂　剛：軟骨由来成長因子Hcs24/CTGFの血管内皮細胞におけるオートクリン，パラクリン増殖・遊走因子としての役割。岡山歯学会雑誌、17、117-133、1998.

59) Yutani, Y., Yano, Y., Ohashi, H.,Takigawa, M. and Yamano, Y.: Cartilaginous differentiation in the jointcapsule.  J. Bone Miner. Metab., 17,7-10,  1999.

60) Kuboki, T., Hattori, T., Mizushima, T.,Kanyama, M., Fujisawa, T., Yamashita, A. and Takigawa, M.: Detection ofspecific antibodies against human cultured chondrosarcoma (HCS-2/8) and osteosarcoma(Saos-2) cells in the serum of patients with osteoarthritis of thetemporomandibular joint. Arch. Oral Biol., 44, 403-414, 1999.

61) Kuboki, T., Nakanishi, T., Kanyama, M.,Sonoyama, W., Fujisawa, T., Kobayashi, K., Ikeda, T., Kubo, T., Yamashita, A.and Takigawa, M.: Direct adenovirus-mediated gene delivery to thetemporomandibular joint in guinea-pigs. Arch. Oral Biol., 44, 701-709, 1999.

62) Fujisawa, T., Hattori, T., Takahashi,K., Kuboki, T., Yamashita, A. and Takigawa, M.: Cyclic mechanical stressinduces extracellular matrix degradation in cultured chondrocytes via geneexpression of matrix metalloproteinases and interleukin-1. J. Biochem., 125,966-975, 1999.

63) Kubo, T., Arai, Y., Takahashi, K.,Ishida, T., Fujisawa, T., Takigawa, M., Imanishi, J. and Hirasawa, Y.: Effectof pressure loading on Interleukin-8 production in chondrocytes.Pathophysiology, 6, 35-39, 1999.

64) Kubota, S., Hattori, T. Nakanishi, T.and Takigawa, M.: Involvement of cis-acting repressive element(s) in the 3'-untranslatedregion of human connective tissue growth factor gene. FEBS Lett., 450, 84-88,1999.

65) Kondo, Y., Nakanishi, T., Takigawa, M.and Ogawa, N.: Immunohistochemical localization of connective tissue growthfactor in the rat central nervous system. Brain Res., 834, 146-151, 1999.

66) Shimo, T., Nakanishi, T., Nishida, T.,Asano, M., Kanyama, M., Kuboki, T., Tamatani, T., Tezuka, K., Takemura, M.,Matsumura, T. and Takigawa, M.: Connective tissue growth factor induces theproliferation, migration and tube formation of vascular endothelial cells invitro and angiogenesis in vivo. J. Biochem., 126, 137-145, 1999.

67) Kubota, S., Copeland,T.D. andPomerantz, R.J.: Nuclear and nucleolar targeting of human ribosomal proteinS25: Common features shared with HIV-1 regulatory proteins.  Oncogene, 18, 1503-1514, 1999.

68) Kubota, S., Zhang, H., Kitahara, S. andPomerantz, R.J.: Role of lentiviral lytic polypeptide ・(LLP-・) in the selectivecytotoxicity of γ-glutamylcysteine ethyl ester against human immunodeficiency virustype 1-producing cells. Antiviral Chemistry & Chemotherapy, 10, 121-127,1999.

69) 藤沢拓生：培養軟骨細胞を用いた周期的メカニカルストレスによる軟骨破壊機序に関する研究。岡山歯学会雑誌、18、83-101、1999。

70) Mori, T., Kawara, S., Shinozaki, M.,Hayashi, N., Kakinuma, T., Igarashi, A., Takigawa, M., Nakanishi, T. andTakehara, K.: Role and interaction of connective tissue growth factor withtransforming growth factor-β in persistent fibrosis: A mouse fibrosis model.  J. Cell. Physiol., 181, 153-159, 1999.

71) Kanyama, M., Kuboki, T., Kojima, S.,Fujisawa, T., Hattori, T., Takigawa, M. and Yamashita, A.: Matrixmetalloproteinases and tissue inhibitors of metalloproteinases in synovialfluids of temporomandibular joint osteoarthritis patients. J. Orofac. Pain, 14,20-30, 1999.

72) Fujiwara, K., Udono, H., Kunisada, T.,Kawai, A., Inoue, H., Takigawa, M., Namba, M. and Nakayama, E.: Electrophoreticand serologic characterization of 56 kDa antigen (M56) with autologous serumderived from a chondrosarcoma patient; a shared antigen of immunoresponses incancer and autoimmune diseases. Electrophoresis, 20, 3335-42,1999.

73) Arai, Y., Kubo, T., Kobayashi, K.,Ikeda, T., Takahashi, K., Takigawa, M., Imanishi, J. and Hirasawa, Y.: Controlof delivered gene expression in chondrocytes using heat shock protein 70Bpromoter. J. Rheumatol., 26,1769-74, 1999.

74) Sato, S., Nagaoka, T., Hasegawa, M.,Tamatani, T., Nakanishi, T., Takigawa, M. and Takehara, K.: Serum levels of connectivetissue growth factor are elevated in patients with systemic sclerosis:Association with the extent of skin sclerosis and the severity of pulmonaryfibrosis. J. Rheumatol., 27, 149-154, 2000.

75) Nishida, T., Nakanishi, T., Asano, M.,Shimo, T. and Takigawa, M.: Effects of CTGF/Hcs24, a hypertrophicchondrocyte-specific gene product, on the proliferation and differentiation ofosteoblastic cells in vitro. J. Cell. Physiol., 184, 197-206, 2000.

76) Nakanishi, T., Nishida, T., Shimo, T.,Kobayashi, K., Kubo, T., Tamatani, T., Tezuka, K. and Takigawa, M.: Effects ofCTGF/Hcs24, a product of a hypertrophic chondrocyte-specific gene, on theproliferation and differentiation of chondrocytes in culture. Endocrinology,141, 264-273, 2000.

77) Ikeda, T., Kubo, T., Nakanishi, T.,Arai, Y., Kobayashi, K., Mazda, O., Ohashi, S., Takahashi, K., Imanishi, J.,Takigawa, M. and Hirasawa, Y.:Ex vivo gene delivery using an adenovirus vectorin treatment for cartilage defects. J. Rheumatol., 27, 990-996, 2000.

78) Asaumi, K., Nakanishi, T., Asahara, H.,Inoue, H. and Takigawa, M.: Expression of neurotrophins and theirreceptors(TRK)during fracture healing. Bone, 26, 625-633, 2000.

79) Shakunaga, T., Ozaki, T., Ohara, N.,Asaumi, K., Doi, T., Nishida, K., Kawai, A., Nakanishi, T., Takigawa, M.andInoue, H.: Expression of connective tissue growth factor in cartilaginoustumors. Cancer, 89, 1466-1473, 2000.

80) Kubota, S., Hattori, T., Shimo, T.,Nakanishi, T. and Takigawa, M.: Novel intracellular effects of human connectivetissue growth factor expressed in Cos-7 cells. FEBS Lett., 474, 58-62, 2000.

81) Kubota, S. and Pomerantz, R.J.: Thenuclear function of the nuclear diffusion inhibitory signal(NIS) of HIV-1:Critical roles in dominant nuclear localization and intraclluar stability. J.Hum. Virol.,  3, 173-181, 2000.

82) Hattori, T., Takahashi, K., Yutani, Y.,Fujisawa, T., Nakanishi, T. and Takigawa, M.: Rheumatoid arthritis relatedantigen 47 kDa(RA-A47) is a product of colligin-2 and acts as a human HSP47. J.Bone Miner. Metab. 18, 328-334, 2000.

83) Kubota, S., Kondo, S., Eguchi, T.,Hattori, T., Nakanishi, T., Pomerantz, R.J. and Takigawa, M.: Identification ofan RNA element that confers post-transcriptional repression of connectivetissue growth factor/hypertrophic chondrocyte specific 24 (ctgf/hcs24) gene:Similarities to retroviral RNA-protein interactions.  Oncogene, 19, 4773-4786, 2000.

84) 服部高子：軟骨細胞様培養細胞株HCS-2/8における慢性関節リウマチ関連抗原RA-A47の炎症性サイトカインによる発現抑制と細胞内局在変化. 岡山歯学会誌, 19, 241-253, 2000.

85) 窪木拓男, 石川邦夫, 荒井英雄, 吉田登志子, 平田あずみ, 市川博之, 舩橋　誠, 久保田　聡, 井上正久, 谷本一郎, 十川紀夫, 入江正郎, 濱　和洋, 伊東高介, 明貝文夫, 完山　学, 白井　肇, 原　哲也, 宮本　学, 谷本裕子, 三島克章, 水川展吉, 竹林俊明, 大山和彦, 繁原　宏, 浅海淳一, 岸本悦央, 山本龍生, 尾形小霧, 西村美智子, 糀谷　淳, 永井教之, 福井一博, 岸　幹二, 渡辺達夫, 松尾龍二, 矢谷博文, 山本照子, 松村智弘, 滝川正春：岡山大学歯学部における問題発見解決型教育法（チュートリアル教育）導入の試み. 岡山歯学会誌, 19, 295-302, 2000.

86) Kondo, S., Kubota, S., Eguchi, T.,Hattori, T., Nakanishi, T., Sugawara, T. and Takigawa, M.: Characterization ofa mouse ctgf 3'-UTR segment that mediates repressive regulation of geneexpression. Biochem. Biophys. Res. Commun., 278, 119-124, 2000.

87) Kobayashi, H., Hirashima, Y., Wei Sun,G., Fujie, M., Nishida, T., Takigawa, M. and Terao, T.: Identity of urinarytrypsin inhibitor-binding protein to link protein. J. Biol. Chem., 275,21185-21190, 2000.

88) Ghayor, C., Herrouin, J.H.,Chadjichristos, C., Ala-Kokko, L., Takigawa, M., Pujol, J.P. and Galera, P.:Regulation of Human COL2A1 Gene Expression in Chondrocytes; indentification ofC-Krox-Responsive elements and modulation by phenoytpe alteration. J. Biol.Chem., 275, 27421-27438, 2000.

89) Miyazaki , I. , Aoki-Sogawa, C., Asanuma,M., Higashi, Y., Tanaka, K., Nakanishi, T. and Ogawa, N.: Expression ofmetallothionein-・ mRNA and its regulation by levodopa in the basal ganglia of hemi-parkinsonianrats. Neuroscience Letters, 293, 65-68, 2000.