論文

2024年

Kawano K, Sakaguchi K, Ninpetch N, Yanagawa Y, Katagiri S. Physiological high temperatures alter the amino acid metabolism of bovine early antral follicles. J Reprod Dev. 2024 Jun 1;70(3):184-191. doi: 10.1262/jrd.2023-096.

2023年

Md Abdus Shabur Talukder, Ahmed Zaky Balboula, Hanako Bai, Manabu Kawahara, Koji Kimura, Masashi Takahashi. IFNT stimulates lysosomal function via type I IFN signaling pathway in pregnant bovine leukocytes. Reproduction. 2023 Nov 6;166(6):411-421. doi: 10.1530/REP-23-0098.

Matsuyama S, Nakamura S, Minabe S, Ohkura S, Kimura K. Effect of a neurokinin 3 receptor-selective agonist administration on the embryos recovered from superovulated cows.Biol Reprod. 2023 Jun 9;108(6):936-944. doi: 10.1093/biolre/ioad039.

Matsuyama S, Nakamura S, Minabe S, Sakatani M, Takenouchi N, Sasaki T, Inoue Y, Iwata H, Kimura K. Deterioration of mitochondrial biogenesis and degradation in the endometrium is a cause of subfertility in cows. Mol Reprod Dev. Mol Reprod Dev. 2023 Mar;90(3):141-152. doi: 10.1002/mrd.23670. Epub 2023 Jan 16.

Bai R, Kusama K, Matsuno Y, Bai H, Sakurai T, Kimura K, Imakawa K. Expression of NFIL3 and CEBPA regulated by IFNT induced-PGE2 in bovine endometrial stromal cells during the pre-implantation period.Front Endocrinol (Lausanne). 2023 Feb 21;14:1075030. doi: 10.3389/fendo.2023.1075030. eCollection 2023.

Ito S, Yamaguchi Y, Kubota S, Yamamoto Y, Kimura K. Immunohistochemical identification of epithelial cell types in the isthmus of bovine oviduct: Comparison with the ampulla.J Reprod Dev. 69(1):18-24. (2023)

Yamamoto Y, Kurokawa M, Ogawa T, Kubota S, Kimura K. Involvement of gap junctions in the increased contraction of bovine oviducts at pre-ovulation observed in vitro. Reproduction. 165(3):301-312. (2023)

2022年

■ Kubota S, Yamamoto Y, Kimura K. A Chinese Medicine, Tokishakuyakusan, Increases Bovine Oviductal Tonus via G Protein-Coupled Estrogen Receptor 1. Biol Pharm Bull. 45(8):1133-1141. (2022)

■ Sugino Y, Sato T, Yamamoto Y, Kimura K. Evaluation of bovine uterine gland functions in 2D and 3D culture system. J Reprod Dev. 68(4):254-261. (2022)

■ Sakai S, Inoue Y, Tanaka K, Yamamoto Y, Iwata H, Kimura K. Hyperthermia alters interleukin-6 production in response to lipopolysaccharide via endoplasmic reticulum stress in bovine endometrial cells. J Cell Physiol, 237:1087-1099. (2022)

2021年

Szóstek-Mioduchowska AZ, Shiotani H, Yamamoto Y, Sadowska A, Wójtowicz A, Kozai K, Hojo T, Kimura K, Skarzynski DJ, Okuda K. Effects of cortisol on prostaglandin F2α secretion and expression of genes involved in the arachidonic acid metabolic pathway in equine endometrium - In vitro study. Theriogenology, 173:221-229. (2021)

■ Sakai S, Yagi M, Fujime N, Kuse M, Sakumoto R, Yamamoto Y, Okuda K, Kimura K. Heat stress influences the attenuation of prostaglandin synthesis by interferon tau in bovine endometrial cells. Theriogenology, 165:52-58. (2021)

■ Tatebayashi R, Nakamura S, Minabe S, Furusawa T, Abe R, Kajisa M, Morita Y, Ohkura S, Kimura K, Matsuyama S. Gene-expression profile and postpartum transition of bovine endometrial side population cells. Biol Reprod, Jan 13;ioab004. doi: 10.1093/biolre/ioab004. (2021)

2020年

■Sakai S, Hatabu T, Yamamoto Y, Kimura K. Alteration of chemokine production in bovine endometrial epithelial and stromal cells under heat stress conditions. Physiol Rep, 8:e14640. doi: 10.14814/phy2.14640. (2020)

■ Yamamoto Y, Ito S, Okuda K, Kimura K. Involvement of activin signal pathway in cyclic apoptosis of the oviductal isthmic epithelium in cows. Theriogenology, 153:143-150. (2020)

Ito S, Yamamoto Y, Kimura K. Analysis of ciliogenesis process in the bovine oviduct based on immunohistochemical classification. Mol Biol Rep, Feb;47(2):1003-1012. doi: 10.1007/s11033-019-05192-w. (2020)

2019年

■ 香西圭輔、徳山翔太、Anna Z Szóstek、登石裕子、角田修男、田谷一善、阪谷美樹、高橋昌志、南保泰雄、Dariusz J Skarzynski、山本ゆき、木村康二、奥田 潔. ウマ子宮内膜における PGF2α自己増幅機構. 馬の科学, Dec. 56(4):282-293 (2019)

■ Yamaguchi T, Maeda M, Ogata K, Abe J, Utsumi T, Kimura K. The effects on the endocrine system under hepatotoxicity induction by phenobarbital and di(2-ethylhexyl)phthalate in intact juvenile male rats. J Toxicol Sci. Jul;44(7): 459-469. (2019)

2018年

■Suzuki T, Sakumoto R, Hayashi KG, Ogiso T, Kunii H, Shirozu T, Kim SW, Bai H, Kawahara M, Kimura K, Takahashi M. Involvement of interferon-tau in the induction of apoptotic, pyroptotic, and autophagic cell death-related signaling pathways in the bovine uterine endometrium during early pregnancy. J Reprod Dev, Dec 14;64(6):495-502. doi: 10.1262/jrd.2018-063. (2018)

■ Nakamura S, Haga S, Kimura K, Matsuyama S.Propionate and butyrate induce gene expression of monocarboxylate transporter 4 and cluster of differentiation 147 in cultured rumen epithelial cells derived from preweaning dairy calves. J Anim SCi, Nov 21;96(11):4902-4911. doi: 10.1093/jas/sky334. (2018)

■ Sakai S, Hagihara N, Kuse M, Kimura K, Okuda K. Heat stress affects prostaglandin synthesis in bovine endometrial cells. J Reprod Dev, Aug 20;64(4):311-317. doi: 10.1262/jrd.2018-051. (2018)

■ Talukder MAS, Balboula AZ, Shirozu T, Kim SW, Kunii H, Suzuki T, Ito T, Kimura K, Takahashi M. Activation of lysosomal cathepsins in pregnant bovine leukocytes. Reproduction, Jun;155(6):515-528 (2018)

■ Bai R, Kusama K, Nakamura K, Sakurai T, Kimura K, Ideta A, Aoyagi Y, Imakawa K. Down-regulation of transcription factor OVOL2 contributes to epithelial-mesenchymal transition in a noninvasive type of trophoblast implantation to the maternal endometrium. FASEB J, Feb;fj201701131RR. doi: 10.1096/fj.201701131RR (2018)

■ Ikeda M, Matsuyama S, Akagi S, Ohkoshi K, Nakamura S, Minabe S, Kimura K, Hosoe M. Publisher Correction: Correction of a Disease Mutation using CRISPR/Cas9-assisted Genome Editing in Japanese Black Cattle. Sci Rep. Jan; 8(1):1470 (2018)

■ Nishie T, Kobayashi Y, Kimura K, Okuda K.: Acute stimulation of a smooth muscle constrictor by oestradiol-17β via GPER1 in bovine oviducts. Reprod Domest Anim Apr;53(2):326-332.(2018)


2017年

■ Ikeda M, Matsuyama S, Akagi S, Ohkoshi K, Nakamura S, Minabe S, Kimura K, Hosoe M.Correction of a Disease Mutation using CRISPR/Cas9-assisted Genome Editing in Japanese Black Cattle. Sci Rep. 2017 Dec 19;7(1):17827. (2017)

■ Nishimura R, Hasegawa H, Yamashita M, Ito N, Okamoto Y, Takeuchi T, Kubo T, Iga K, Kimura K, Hishinuma M, Okuda K.: Hypoxia increases glucose transporter 1 expression in bovine corpus luteum at the early luteal stage. J Vet Med Sci, Nov 17;79(11):1878-1883. (2017)

■ Tanikawa N, Seno K, Kawahara-Miki R, Kimura K, Matsuyama S, Iwata H, Kuwayama T, Shirasuna K.: Interferon Tau Regulates Cytokine Production and Cellular Function in Human Trophoblast Cell Line. J Interferone Cytokine Res, 37 (10):456-466 (2017)

■ Tanikawa N, Ohtsu A, Kawahara-Miki R, Kimura K, Matsuyama S, Iwata H, Kuwayama T, Shirasuna K: Age-associated mRNA expression changes in bovine endometrial cells in vitro. Reprod Biol Endocrinol, 15 (1):63. (2017)

■ Fujii T, Hirayama H, Naito A, Kashima M, Sakai H, Fukuda S, Ypshino H, Moriyasu S, Kageyama S, Sugimoto Y, Matsuyama S, Hayakawa H, Kimura K: Production of calves by the transfer of cryopreserved bovine elongating conceptuses and possible application for preimplantation genomic selection. J Reprod Dev, 63 (5):497-504. (2017)

■ Shirozu T, Iwano H, Ogiso T, Suzuki T, Balboula AZ, Bai H, Kawahara M, Kimura K, Takahashi H, Rulan B, Kim S, Yanagawa Y, Nagano M, Imakawa K, Takahashi M:Estrous cycle stage-dependent manner of type I interferon-stimulated genes induction in the bovine endometrium. J Reprod Dev,Jun 21;63(3):211-220. doi: 10.1262/jrd.216-176 (2017)

■ Yoshimoto Y, Nishie T, Ito S, Kobayashi Y, Yamamoto Y, Okuda K, Kimura K: Adrenomedullin regulates the speed of oviductal fluid flow in cattle. Mol Reprod Dev,84 (8):712-718. doi: 10.1002/mrd.22852 (2017)

■ Fadhillah, Yoshioka S, Nishimura R, Yamamoto Y, Kimura K, Okuda K: Hypoxia-inducible factor 1 mediates hypoxia-enhanced synthesis of progesterone during luteinization of granulosa cells. J Reprod Dev, Feb;63(1):75-85. doi: 10.1262/jrd.2016-068 (2017)

■ Horihata K, Yoshioka S, Sano M, Yamamoto Y, Kimura K, Skarzynski DJ, Okuda K: Expressions of lipoprotein receptors and cholesterol efflux regulatory proteins during luteolysis in bovine corpus luteum. Reprod Fertil Dev, Jul;29(7):1280-1286. doi: 10.1071/RD15538. (2017)

2016年

■ Kimura K: Superovulation with a single administration of FSH in aluminum hydroxide gel: a novel superovulation method for cattle, J Reprod Dev, 62(5):423-429.(2016) Review

■Sinderewicz E, Grycmacher K, Boruszewska D, Kowalczyk-Zięba I, Yamamoto Y, Yoshimoto Y, Woclawek-Potocka I: Lysophosphatidic Acid Synthesis and its Receptors' Expression in the Bovine Oviduct During the Oestrous Cycle. Reprod Domest Anim, 51(4):541-9. doi: 10.1111/rda.12717 (2016)

■ Hashiba K, Nio-Kobayashi J, Sano M, Maeda M, Kimura Y, Yamamoto Y, Kimura K, Okuda K: Possible contribution of α2,6-sialylation to luteolysis in cows by inhibiting the luteotrophic effects of galectin-1.Biol Reprod, Jul;95(1):17. doi: 10.1095/biolreprod. 116.140194 (2016)

■ Ito S, Kobayashi Y, Yamamoto Y, Kimura K, Okuda K: Remodeling of bovine oviductal epithelium by mitosis of secretory cells. Cell Tissue Res, Nov;366(2): 403-410. doi: 10.1007/s00441-016-2432-8 (2016)

Kobayashi Y, Yoshimoto Y, Yamamoto Y, Kimura K, Okuda K: Roles of EDNs in regulating oviductal NO synthesis and smooth muscle motility in cows. Reproduction, 151(6): 615-622. doi: 10.1530/REP-15-0586 (2016)

Kobayashi Y, Yamamoto Y, Kageyama S, Hirayama H, Kimura K, Okuda K: Regulation of bovine oviductal NO synthesis by follicular steroids and prostaglandins. Reproduction, 151(6): 577-587. doi: 10.1530/REP-15-0254 (2016)

Kozai K, Tokuyama S, Szóstek AZ, Toishi Y, Tsunoda N, Taya K, Sakatani M, Takahashi M, Nambo Y, Skarzynski DJ, Yamamoto Y, Kimura K, Okuda K: Evidence for a PGF2α auto-amplification system in the endometrium in the mare. Reproduction, 151(5): 517-526. doi: 10.1530/REP-15-0617 (2016)

Yoshimoto Y, Kobayashi Y, Wocławek-Potocka I, Sinderewicz E, Yamamoto Y, Kimura K, Okuda K: Local effect of lysophosphatidic acid on prostaglandin production in the bovine oviduct. Reprod Fertil Dev, 29(5) 1021-1028. doi: 10.1071/RD15409 (2016)

田村 隆, 揖斐 隆之, 稲垣 賢二, 久保 康隆, 奥田 潔: 大学生の朝食欠食習慣の統計解析と改善への新指針 岡山大学農学部学術報告, Vol. 105, 1-5 (2016)

■ Nio-Kobayashi J, Hashiba K, Sano M, Okuda K, Duncan DC, Iwanaga T: Expression profiles and possible roles of galectins in the corpus luteum. Trends Glycosci Glycotechnol, 28:162 ;E71-E77 (2016)

2015年

■ Bai R, Kusama K, Sakurai T, Bai H, Wang C, Zhang J, Kuse M, Ideta A, Aoyagi Y, Okuda K, Imakawa K: The role of endometrial selectins and their ligands on bovine conceptus attachment to the uterine epithelium during peri-implantation period. Biol Reprod; 93:46 doi:10.1095/biolreprod.115.128652 (2015)

Sano M, Hashiba K, Nio-Kobayashi J, Okuda K: The luteotrophic function of galectin-1 by binding to the glycans on VEGFR-2 in bovine luteal cells. J Reprod Dev, 61(5): 439-448 (2015)

Sano M, Hashiba K, Higashi M, Okuda K: Alteration of glycan structures by swainsonine affects steroidogenesis in bovine luteal cells. Theriogenology, 15;84(5):827-32. doi: 10.1016/j.theriogenology.2015.05.026 (2015)

■ Takatsu K, Kuse M, Yoshioka S, Acosta TJ: Expression of epidermal growth factor (EGF) and its receptor in bovine endometrium throughout the luteal phase: effects of EGF on prostaglandin production in endometrial cells. Anim Reprod, 12(2): 328-335 (2015)

■ Takatsu K, Acosta TJ: Expression of heparin-binding EGF-like growth factor (HB-EGF) in bovine endometrium: effects of HB-EGF and interferon-τ on prostaglandin production. Reprod Domest Anim, 50(3): 458-464 (2015)

■ Abe H, Sakumoto R, Okuda K: Expression of matrix metalloproteinases in bovine luteal cells induced by prostaglandin F2α, interferon γ and tumor necrosis factor α. J Reprod Dev, 61(4): 277-286 (2015)

■ Kuse M, Sakumoto R, Okuda K: Genomic and non-genomic effects of progesterone on prostaglandin (PG) F2α and PGE2 production in the bovine endometrium. Reprod Fertil Dev, 28(10) 1588-1597. doi: 10.1071/RD14490 (2015)

■ Abeoelenain M, Kawahara M, Montasser A, Zaabel SM, Okuda K, Takahashi M: Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle. J Reprod Dev, 61(3): 229-236 (2015)

■ Hirata R, Hojo T, Sano M, Hayashi N, Okuda K: Potential role of hCG in apoptosis of human luteinized granulosa cells. J Reprod Dev, 61(1): 42-48 (2015)

■ Sakumoto R, Hayashi K, Hosoe M, Iga K, Kizaki K, Okuda K: Gene expression profiles in the bovine corpus luteum (CL) during the estrous cycle and pregnancy: possible roles of chemokines in regulating CL function during pregnancy. J Reprod Dev, 61(1): 67-73 (2015)

■ Nishimura R, Okuda K: Multiple roles of hypoxia in ovarian function: roles of HIF-related and -unrelated signals during luteal phase. Reprod Fertil Dev, 28(10) 1479-1486. doi: 10.1071/RD15010 (2015)

2014年


■ Yamamoto Y, Kohka M, Kobayashi Y, Woclawec-Potocka I, Okuda K: Endothelin as a local regulating factor in the bovine oviduct. Reprod Fertil Dev, doi: 10.1071/ RD14076 (2014)

■ Arai M, Yoshioka S, Nishimura R, Okuda K: FAS/FASL-mediated cell death in the bovine endometrium. Anim Reprod Sci, 151, 97-104, DOI: 10.1016/j.anireprosci. 2010.10.004 (2014)

Hashiba K, Sano M, Nio-Kobayashi J, Hojo T, Skarzynski DJ, Okuda K: Galectin-3 contributes to luteolysis by binding to β1 integrin in the bovine corpus luteum.
Biol Reprod, 91 (1): 1-10, doi: 10.195/biolreprod.114.119057 (2014)

■ Kawasaki Y, Aoki Y, Magata F, Miyamoto A, Kawashima C, Hojo T, Okuda K, Shirasuna K, Shimizu T: The effect of single nucleotide polymorphisms in the tumor necrosis factor-α gene on reproductive performance and immune function in dairy cattle. J Reprod Dev, 60 (3): 173-178 (2014)

Hai V Vu, Acosta TJ: Catalase and glutathione peroxidase expression in bovine corpus luteum during the estrous cycle and their modulation by prostaglandin F2α and H2O2. Anim Reprod, http://revistas.bvs-vet.org.br/animreprod/article/view/27250

Bai R, Bai H, Kuse M, Ideta A, Aoyagi Y, Fujiwara H, Okuda K, Imakawa K, Sakurai T: Involvement of VCAM1 in the bovine conceptus adhesion to the uterine endometrium. Reproduction, 148 119-127 (2014)

Jursza E, Szostek A, Kowalewski MP, Boos A, Okuda K, Siemieniuch M: LPS-challenged TNFα production, prostaglandin secretion, and TNFα/TNFRs expression in the endometrium of domestic cats in estrus or diestrus, and in cats with pyometra or receiving nedroxyprogesterone acetate. Mediators Inflamm, http://dx.doi.org/10.1155/2014/689280

■ Takahashi H, Tsunazaki M, Hamano T, Takahashi M, Okuda K, Inumaru S, Okano A, Geshi M, Hirako M: Biological activity of recombinant bovine interferon τ produced by a silkworm-baculovirus gene expression system. J Vet Med Sci, 76 (3): 447-451 (2014)

■ Kumagai A, Yoshioka S, Sakumoto R, Okuda K: Auto-amplification system for prostaglandin F2α in bovine corpus luteum. Mol Reprod Dev, 81 (7): 646-654, doi: 10.1002/mrd.22332 (2014)

■ Bai H, Sakurai T, Bai R, Yamakoshi S, Aoki E, Kuse M, Okuda K, Imakawa K: Establishment and characterization of immortalized bovine endometrial epithelial cells. Anim Sci J, 85 (8): 799-804, doi: 10.1111/asj.12202 (2014)

■ Fadhillah, Yoshioka S, Nishimura R, Okuda K: Hypoxia promotes progesterone synthesis during luteinization in bovine granulosa cells. J Reprod Dev, 60 (3): 194-201 (2014)

■ Korzekwa AJ, Lukasik K, Pilawski W, Piotrowska-Tomala KK, Jaroszewski JJ, Yoshioka S, Okuda K, Skarzynski DJ: Influence of prostaglandin F2α analogues on the secretory function of bovine luteal cells and ovarian arterial contractility in vitro.
Vet J, 199, 131-137 (2014)

■ Abe H, Al-zi'abi MO, Sekizawa F, Acosta TJ, Skarzynski DJ, Okuda K: Lymphatic involvement in the disappearance of steroidogenic cells from the corpus luteum during luteolysis.
PLOS ONE, 20; 9 (2): e88953 doi: 10.1371/journal.pone.0088953 (2014)

■ Szóstek AZ, Galvao A, Hojo T, Okuda K, Skarzynski DJ: Interleukins affect equine endometrial cell function: modulatory action of ovarian steroids.
Mediators Inflamm, doi: 10.1155/2014/208103 (2014)

■ Kozai K, Hojo T, Tokuyama S, Szóstek AZ, Takahashi M, Sakatani M, Nambo Y, Skarzynski DJ, Okuda K: Expression of aldo-keto reductase 1C23 in equine corpus luteum at different luteal phases.
J Reprod Dev, 60 (2): 150-154 (2014)

■ 西村亮, 奥田潔:卵巣の機能調節における低酸素環境の生理的意義.
「生殖内分泌学会誌」 19: 31-36 (2014)

2013年

■ Yoshioka S, Abe H, Sakumoto R, Okuda K: Proliferation of luteal steroidogenic cells in cattle.
PLOS ONE, doi: 10.1371/journal.pone.0084186 (2013)

■ Toishi Y, Tsunoda N, Tagami M, Hashimoto H, Kato F, Suzuki T, Nagaoka K, Watanabe G, Tokuyama S, Okuda K, Taya K: Evaluation of the PATHFAST chemiluminescent enzyme immunoassay for measuring progesterone in whole blood and serum of mares.
J Equine Sci, 24 (3): 47–51 (2013)

■ Yamamoto Y, Kobayashi Y, Okuda K: Purified culture systems for bovine oviductal stromal cells.
J Reprod Dev, 60(1): 73-77(2013)

■ Arai M, Yoshioka S, Tasaki Y, Okuda K: Remodeling of bovine endometrium throughout the estrous cycle.
Anim Reprod Sci, 142 (1-2): 1-9 (2013)

■ Kobayashi Y, Wakamiya K, Kohka M, Yamamoto Y, Okuda K: Summer heat stress affects prostaglandin synthesis in the bovine oviduct.
Reproduction, 146 (2): 103-110 (2013)

■ Hai V Vu, Dam TV, Acosta TJ: Regulation of superoxide dismutase by prostaglandin F2α in the bovine corpus luteum.
Anim Reprod, 10 (2): 88-98 (2013)

Iwazawa M, Acosta TJ: Effect of elevated temperatures on bovine corpus luteum function: Expression of heat shock protein 70, cell viability and production of progesterone and prostaglandins by cultured luteal cells.
Anim Prod Sci, 54(3): 285-291 (2013)

■ Sakurai T, Bai H, Bai R, Sato D, Arai M, Okuda K, Ideta A, Aoyagi A, Godkin JD, Imakawa K: Down-regulation of interferon tau gene transcription with a transcription factor, EOMES.
Mol Reprod Dev, 80 (5): 371-383 (2013)

■ Kuse M, Lee HY, Acosta TJ, Hojo T, Okuda K: Expression of glucocorticoid receptor α and its regulation in the bovine endometrium: Possible role in cyclic prostaglandin F2α production.
J Reprod Dev, 59(4): 346-352 (2013)

Kawaguchi S, Bowolaksono A, Yoshioka S, Sakumoto R, Okuda K: Luteoprotective mechanisms of prostaglandin F2α stimulated by luteinizing hormone in the bovine corpus luteum.
J Reprod Dev, 59 (3): 225-230 (2013)

■ Kawaguchi S, Sakumoto R, Okuda K: Induction of the expressions of antioxidant enzymes by luteinizing hormone in the bovine corpus luteum.
J Reprod Dev, 59 (3): 219-224 (2013)

Kawaguchi S, Bowolaksono A, Sakumoto R, Okuda K: Luteoprotective roles of luteinizing hormone are mediated by not only progesterone production but also glucocorticoid conversion in bovine corpus luteum.
Mol Reprod Dev, 80 (3): 204-215 (2013)

2012年

■ Abe M, HojoT, Kozai K, Okuda K
Possible role of insulin-like factor 3 in the bovine corpus luteum.
J Vet Med Sci, 75 (5): 629-632 (2013).

■ Hai V Vu, Acosta TJ, Yoshioka S, Abe H, Okuda K: Roles of prostaglandin F2alpha and hydrogen peroxide in the regulation of copper/zinc superoxide dismutase in bovine corpus luteum and luteal endothelial cells.
Reprod Biol Endocrinol, 10, 87 (2012)

■ Yoshioka S, Acosta TJ, Okuda K: Roles of cytokines and progesterone in the regulation of the nitric oxide generating system in bovine luteal endothelial cells.
Mol Reprod Dev, 79, 689-696 (2012)

■ Sakurai T, Bai H, Bai R, Arai M, Iwazawa M, Zhang J, Konno T, Godkin JD, Okuda K, Imakawa K: Co-culture system that mimics in vivo attachment processes in bovine trophoblast cells.
Biol Reprod, 87 (3): 60, 1-11 (2012)

■ Piotrowska-Tomala KK, Siemieniuch MJ, Szostek AZ, Korzekwa A, Woclawek-Potocka I, Galváo AM, Okuda K, Skarzynski DJ: Lipopolysaccharides, cytokines and nitric oxide affect secretion of prostaglandins and leukotrienes by bovine mammary gland epithelial cells.
Domest Anim Endocrinol,43 (4): 278-288 (2012)

■ Kozai K, Hojo T, Takahashi M, Acosta TJ, Nambo Y, Okuda K: Seasonal changes in luteal progesterone concentration and mRNA expressions of progesterone synthesis-related proteins in the corpus luteum of mares.
J Reprod Dev, 58 (4): 393-397 (2012)

■ Duong H, Skarzynski D, Piotrowska-Tomala KK, Bah M, Jankowska P, Lukasik K, Okuda K, Acosta TJ: Conversion of cortisone to cortisol and prostaglandin F2α production by the reproductive tract of cows at the late luteal stage in vivo.
Reprod Domest Anim, 47, 939-945 (2012)

■ Majewska M, Lee HY, Tasaki Y, Acosta TJ, Szostek AZ, Siemieniuch M, Okuda K, Skarzynski DJ: Is cortisol a modulator of interferon tau action in the endometrium during early pregnancy in cattle?
J Reprod Immunol, 93, 82-93 (2012)

■ Sekizawa F, Sawai K, Tanaka M, Okuda K: Relationship between embryo collection results after superovulation treatment of japanese black cows and their plasma β-carotene and vitamin concentrations.
J Reprod Dev, 58 (3): 377-379 (2012)

■ Duong HT, Piotrowska-Tomala KK, Acosta TJ, Bah MM, Sinderewicz E, Majewska M, Jankowska K, Okuda K, Skarzynski DJ: Effects of cortisol on pregnancy rate and corpus luteum function in heifers: an in vivo study.
J Reprod Dev, 58 (2): 223-230 (2012)

■ Shimizu T, Kaji A, Murayama C, Magata F, Shirasuna K, Wakamiya K, Okuda K, Miyamoto A: Effects of interleukin-8 on estradiol and progesterone production by bovine granulosa cells from large follicles and progesterone production by luteinizing granulosa cells in culture.
Cytokine, 57 (1): 175-181 (2012)

■ Duong H, Vu H, Bah M, Woclawek-Potocka I, Dam T, Skarzynski D, Okuda K, Acosta TJ: Acute changes in the concentrations of prostaglandin F2α (PGF) and cortisol in uterine and ovarian venous blood during PGF-induced luteolysis in cows.
Reprod Domest Anim, 47 (2): 238-243 (2012)

2011年

■Szostek AZ, Siemieniuch MJ, Deptula K, Woclawek-Potocka I, Majewska M, Okuda K, Skarzynski DJ: Ovarian steroids modulate tumor necrosis factor-α and nitric oxide- regulated prostaglandin secretion by cultured bovine oviductal epithelial cells. Domest Anim Endocrinol, 41, 14-23 (2011)

■ Sakumoto R, Vermehren M, Kenngott RA, Okuda K, Sinowatz F: Localization of gene and protein expressions of tumor necrosis factor-α (TNF), and TNF receptor types I and II in the bovine corpus luteum during the estrous cycle.
J Anim Sci, 89 (10): 3040-3047 (2011)

■ Szostek AZ, Lukasik L, Majewska M, Bah MM, Znaniecki R, Okuda K, Skarzynski DJ: Tumor necrosis factor-α inhibits the stimulatory effect of luteinizing hormone and prostaglandin E2 on progesterone secretion by the bovine corpus luteum.
Domest Anim Endocrinol, 40, 183-191 (2011)

■ Kamemori Y, Wakamiya K, Nishimura R, Hosaka Y, Ohtani S, Okuda K: Expressions of apoptosis-regulating factors in bovine retained placenta. Placenta, 32(1): 20-26 (2011)

■ Siemieniuch MJ, Mlynarczuk JJ, Skarzynski DJ, Okuda K: Possible involvement of oxytocin and its receptor in the local regulation of prostaglandin secretion in the cat endometrium.
Anim Reprod Sci, 123, 89-97 (2011)

2010年


Siemieniuch MJ, Majewska M, Takahashi M, Sakatani M, Lukasik K, Okuda K, Skarzynski DJ: Are glucocorticoids auto- and/or paracrine factors in early bovine embryo development and implantation?
Reproductive Biology, 10(3): 249-256 (2010)

Okuda K, Sakumoto R, Okamoto N, Acosta TJ, Abe H, Okada H, Sinowatz F, Skarzynski DJ: Cellular localization of genes and proteins for tumor necrosis factor-α (TNF), TNF receptor types I and II in bovine endometrium.
Mol Cell Endocrinol, 330(1-2): 41-48 (2010)

Tetsuka M, Nishimoto H, Miyamoto A, Okuda K, Hamano S: Gene expression of 11β-HSD and glucocorticoid receptor in bovine (Bos taurus) follicle during follicular maturation and atresia: The role of follicular stimulating hormone.
J Reprod Dev, 56(10): 616-622 (2010)

Siemieniuch MJ, Ogrodowska K, Ohgawara H, Skarzynski DJ, Okuda K: Tumor necrosis factor-α as a possible auto-/paracrine factor affecting estrus cycle in the cat uterus.
Polish J Vet Sci, 13(4): 605-613 (2010)

Lee SH, Acosta TJ, Nakagawa Y, Okuda K: Role of nitric oxide in the regulation of superoxide dismutase and prostaglandin F2α production in bovine luteal endothelial cells.
J Reprod Dev, 56(4): 454-459 (2010)


Hojo T, Oda A, Lee SH, Acosta TJ, Okuda K: Effect of tumor necrosis factor α (TNF) and interferon γ on the viability and mRNA expression of TNF receptor type Ⅰ in the endothelial cells from bovine corpus luteum.
J Reprod Dev, 56(5): 515-519 (2010)

Korzekwa A, Acosta TJ, Miklewiez M, Okuda K, Lee SH, Skarzynski DJ: Leukotrienes affect secretory function of ovarian cells in vitro.
Reprod Domest Anim, 45(6): e288-e296 (2010)

Siemieniuch M, Bowolaksono, Skarzynski DJ, Okuda K: Ovarian steroids regulate prostaglandin secretion in the feline endometrium.
Anim Reprod Sci, 120, 142-150 (2010)

Sakumoto R, Vermehren M, Kenngott R, Okuda K, Sinowatz F: Changes in the levels of progesterone receptor mRNA and protein in the bovine corpus luteum during the estrous cycle.
J Reprod Dev, 56(2): 219-222 (2010)

Tasaki Y, Nishimura R, Shibaya M, Lee HY, Acosta TJ, Okuda K: Expression of VEGF and its receptors in the bovine endometrium throughout the estrous cycle: effects of VEGF on prostaglandin production in endometrial cells.
J Reprod Dev, 56(2): 223-229 (2010)

Hojo T, Al-zi'abi MO, Komiyama J, Manabe N, Acosta TJ, Okuda K: Expression and localization of cFLIP, an anti-apoptotic factor, in the bovine corpus luteum.
J Reprod Dev, 56 (2): 230-235 (2010)


Majewska M, Woclawel-Potocka I, Bah M, Hapunik J, Piotrowska K, Tasaki Y, Acosta TJ, Okuda K, Skarzynski DJ: Is interleukin-1α luteotrophic or luteolytic agent in cattle?
Reproduction, 139 (3): 665-672 (2010)

Nishimura R, Okuda K: Hypoxia is important for establishing vascularization during corpus luteum formation in cattle.
J Reprod Dev, 56 (1): 110-116 (2010)

Skarzynski DJ, Okuda K: Inter- and intra-cellular mechanisms of prostaglandin F2α action during corpus luteum regression in cattle.
Nottingham University Press,Volume 7, Number 1, 20, 303-322 (2010)

2009年

Hojo T, Al-zi'abi MO, Skarzynski DJ, Acosta TJ, Okuda K: Changes in the vasculature of bovine corpus luteum during the estrous cycle and prostaglandin F2α-induced luteolysis. 
J Reprod Dev, 55 (5): 512-517 (2009)

Siemieniuch M, Woclaweak-Potocka I, Deptula K, Okuda K, Skarzynski DJ: Effects of tumor necrosis factor-α and nitric oxide on prostaglandins secretion by the bovine oviduct differ in the isthmus and ampulla and depend on the phase of the estrous cycle.
Exp Biol Med, 234 (9): 1056-1066 (2009)

Lee SH, Acosta TJ, Yoshioka S, Okuda K: Prostaglandin F2α regulates the nitric oxide generating system in bovine luteal endothelial cells.
J Reprod Dev, 55 (4): 418-424 (2009)

Taniguchi H, Komiyama J, Viger RV, Okuda K: The expression of the nuclear receptors NR5A1 and NR5A2 and transcription factor GATA6 correlates with steroidogenic gene expression in the bovine corpus luteum.
Mol Reprod Dev, 76 , 873-880 (2009)

Hama N, Kanemitsu H, Tanikawa M, Shibaya M, Sakamoto K, Oyama Y, Acosta TJ, Ishikawa O, Wang PY, Okuda K: Development of an enzyme-immunoassay for urinary pregnanediol-3-glucuronide in a femele giant panda (Ailuropoda melanoleuca).
J Vet Med Sci, 71 (7): 879-884 (2009)

Acosta TJ, Bah MM, Korzekwa A, Woclawek-Potocka I, Markiewicz W, Jaroszewski JJ, Okuda K, Skarzynski DJ: Acute changes in circulating concentrations of progesterone, nitric oxide and partial pressure of oxygen during prostaglandin F2α induced luteolysis in cattle.
J Reprod Dev, 55 (2): 149-155 (2009)


Al-zi'abi MO, Bowolaksono A, Okuda K: Survival role of locally produced acetylcholine in the bovine corpus luteum.
Biol Reprod, 80 (4): 823-832 (2009)

Lee HY, Acosta TJ, Skarzynski DJ, Okuda K: Prostaglandin F2α stimulates 11β-hydroxysteroid dehydrogenase 1 enzyme bioactivity and protein expression in bovine endometrial stromal cells.
Biol Reprod, 80 (4): 657-664 (2009)

Skarzynski DJ, Piotrowska KK, Bah MM, Korzekwa A, Woclawek-Potocka I, Sawai K, Okuda K: Effects of exogenous tumour necrosis factor-α on the secretory function of the bovine reproductive tract depend on tumour necrosis factor-α concentrations.
Reprod Domest Anim, 44, 371-379 (2009)

Woclawek-Potacka I, Komiyama J, Saulnier-Blache J, Brzezicka E, Bah M, Okuda K, Skarzynski D: Lysophosphatic acid modulates prostaglandin secretion in the bovine uterus.
Reproduction, 137 (1): 95-105 (2009)

2008年

Korzekwa A, Murakami S, Woclawek-Potocka I,  Bah MM, Okuda K, Skarzynski DJ: The influence of tumor necrosis factorα (TNF) on the secretory function of bovine corpus luteum: TNF and its receptors expression during the estrous cycle.
Reprod Biol, 8 (3): 245-262 (2008)

Tanikawa M, Lee HY, Watanabe K, Majewska M, Skarzynski DJ, Park S-B, Lee D-S, Park C-K, Acosta TJ, Okuda K: Regulation of prostaglandin biosynthesis by interleukin-1 in cultured bovine endometrial cells.
J Endocrinol, 199, 425-434 (2008)

Hama N, Kanemitsu H, Sakamoto K, Oyama Y, Acosta TJ, Ishikawa O, Pengyan W, Okuda K: Development and evaluation of a rapid enzyme-immunoassay system for measurement of the urinary concentration of estrone-3-glucuronide in a female giant panda (Ailuropoda melanoleuca).
J Reprod Dev, 54 (4): 281-285 (2008)

Khalaj M, Abbasi AR, Nishimura R, Akiyama K, Tsuji T, Noguchhi J, Okuda K, Kunieda T: Leydig cell hyperplasia in an ENU-induced mutant mouse with germ cell depletion.
J Reprod Dev, 54 (3): 225-228 (2008)

Bowolaksono A, Nishimura R, Hojo T, Sakumoto R, Acosta TJ, Okuda K: Anti-apoptotic roles of prostaglandin E2 and F2α in bovine luteal steroidogenic cells.Biol Reprod, 79 (2): 310-317 (2008)

Nishimura R, Komiyama J, Tasaki Y, Acosta TJ, Okuda K: Hypoxia promotes luteal cell death in bovine corpus luteum.
Biol Reprod, 78 (3): 529-536 (2008)

Komiyama J, Nishimura R, Lee HY, Sakumoto R, Tetsuka M, Acosta T, Skarzynski DJ, Okuda K: Cortisol is a suppressor of apoptosis in bovine corpus luteum.
Biol Reprod, 78 (5): 888-895 (2008)

Sakumoto R, Ito I, Okuda K: Changes in expression of 11β-hydroxysteroid dehydrogenase type-1, type-2 and glucocorticoid receptor mRNAs in porcine corpus luteum during the estrous cycle.
Mol Reprod Dev, 75 (5): 925-930 (2008)

Skarzynski DJ, Ferreira-Dias G, Okuda K: Regulation of luteal function and corpus luteum regression in cows: hormonal control, immune mechanisms and inter-cellular communication
Reprod Domest Anim, 43 (Suppl. 2), 57-65 (2008)

2007年

Kobayashi S-I, Sakatani M, Kobayashi S, Okuda K, Takahashi M: Gene silencing of cyclooxygenase-2 mRNA by RNA interference in bovine cumulus-granulosa cells.
J Reprod Dev, 53 (6): 1305-1311 (2007)

Shibaya M, Matsuda A, Hojo T, Acosta TJ, Okuda K: Expressions of estrogen receptors in bovine corpus luteum: cyclic changes and effects of prostaglandin F2α and cytokines.
J Reprod Dev, 53 (5): 1059-1068 (2007)

Skarzynski DJ, Shibaya M, Tasaki Y, Korzekwa A, Murakami S, Woclawek-Potocka I, Majewska M, Okuda K: Fas-mediated apoptosis is suppressed by calf serum in cultured bovine luteal cells.
Reprod Biol, 7 (1): 3-15 (2007)

Skarzynski DJ, Woclawek-Potocka I, Korzekwa A, Bah MM, Piotrowska K, Barszczewska B, Okuda K: Infusion of exogenous tumor necrosis factor dose dependently alters the length of the luteal phase in cattle: differential response to treatment with indomethacin and L-NAME, a nitric oxide synthase inhibitor.Biol Reprod, 76 (4): 619-627 (2007)

Lee HY, Acosta TJ, Tanikawa M, Sakumoto R, Kom iyama J, Tasaki Y, Piskula M, Skarzynski DJ, Tetsuka M, Okuda K: The role of glucocorticoid in the regulation of prostaglandin biosynthesis in non-pregnant bovine endometrium.
J Endocrinol, 193 (1): 127-135 (2007)

Acosta TJ, Yoshioka S, Komiyama J, Lee SH, Grazul-Bilska AT, Skarzynski DJ, Okuda K: Effects of storage and passage of luteal endothelial cells on endothelin-1 and prostaglandin F2α production.
J Reprod Dev, 53 (3): 473-480 (2007)

■ Korzekwa A, Woclawek-Potocka I, Okuda K, Acosta TJ, Skarzynski DJ: Nitric oxide in bovine corpus luteum: possible mechanisms of action in luteolysis.
Anim Sci J, 78 (3): 233-242 (2007)

■ Acosta TJ: Studies of follicular vascularity associated with follicle selection and ovulation in cattle.
J Reprod Dev, 53 (1): 39-44 (2007)

■ Sugino N, Okuda K: Species-differences in the mechanism for apoptosis during structural luteolysis.
J Reprod Dev, 53 (5): 977-986 (2007)

■ 奥田 潔,作本 亮介:牛子宮のプロスタグランジンF2α 分泌調節機構に関する最近の知見と考察. 「家畜診療」 54 (12): 713-723 (2007)

■ 奥田 潔:直腸検査の問題点とその背景.
「家畜人工授精」 239 (3): 20-30 (2007)

2006年

■ Woclawek-Potocka I, Borkowski K, Korzekwa A, Okuda K, Skarzynski DJ: Phyto- and endogenous estrogens differently activate intracellular  calcium ion mobilization in the bovine endometrial cells. J Reprod Dev, 52 (6): 731-740 (2006)

■ Korzekwa AJ, Okuda K, Woclawek-Potocka I, Murakami S, Skarzynski DJ: Nitric oxide induces apoptosis in bovine luteal cells. J Reprod Dev, 52 (3): 353-361 (2006)

■ Nishimura R, Sakumoto R, Tatsukawa Y, Acosta TJ, Okuda K: Oxygen concentration is an important factor for modulating progesterone synthesis in bovine corpus luteum. Endocrinology, 147 (9): 4273-4280 (2006)

■ Tatsukawa Y, Bowolaksono A, Nishimura R, Komiyama J, Acosta TJ, Okuda K: Possible roles of intracellular cyclic AMP, protein kinase C and calcium ion in the apoptotic signaling pathway in bovine luteal cells. J Reprod Dev, 52 (4): 517-522 (2006)

■ Woclawek-Potocka I, Bober A, Korzekwa A, Okuda K, Skarzynski DJ: Equol and para-ethyl-phenol stimulate prostaglandins F2α in bovine corpus luteum. Prostaglandins other Lipid Mediat, 79, 287-297 (2006)

■ Sakumoto R, Komatsu T, Kasuya E, Saito T, Okuda K: Expression of mRNAs for interleukin-4, interleukin-6 and their receptors in porcine corpus luteum during the estrous cycle. Domest Anim Endocrinol, 31 (3): 246-257 (2006)

■ Bah MM, Acosta T, Pilawski W, Deptula KM, Okuda K, Skarzynski DJ: Role of intraluteal prostaglandin F2α, progesterone and oxytocin in basal and pulsatile progesterone release from developing bovine corpus luteum. Prostaglandins other Lipid Mediat, 79, 218-229 (2006)

■ Shibaya M, Murakami S, Tatsukawa Y, Skarzynski DJ, Acosta TJ, Okuda K: Bovine corpus luteum is an extrapituitary site of prolactin production. Mol Reprod Dev, 73, 512-519 (2006)

■ Okuda K, Sakumoto R: Regulation of uterine function by cytokines in cows Possible actions of tumor necrosis factor-α and interferon-τ: Anim Sci J, 77, 266-274 (2006)

 

2005年

■ Woclawek-Potocka I, Okuda K, Acosta TJ, Korzekwa A, Pilawaski W, Skarzynski DJ: Phytoestrogen metabolites are much more active than phytoestrogens themselves in increasing prostaglandin F2α synthesis via prostaglndins F2α synthase-like 2 stimulation in bovine endometrium. Prostaglandins other Lipid Mediat, 78, 202-217 (2005)

■ Woclawek-Potocka I, Acosta TJ, Korzekwa A, Bah MM, Shibaya M, Okuda K, Skarzynski DJ: Phytoestrogens modulate prostaglandin production in bovine endometrium: cell type specifity and intracellular mechanisms. Exp Biol Med, 230, 326-333 (2005)

■ Tanikawa M, Acosta TJ, Fukui T, Murakami S, Korzekwa A, Skarzynski DJ, Piotrowska KK, Park C-K, Okuda K: Regulation of prostaglandin synthesis by interleukin-1α in bovine endometrium during the estrous cycle. Prostaglandins other Lipid Mediat, 78, 279-290 (2005)

■ Shibaya M, Deptula KM, Korzekwa A, Okuda K, Skarzynski DJ: Involvement of the cytoskeleton in oxytocin secretion by cultured bovine luteal cells. Biol Reprod, 72 (1), 200-205 (2005)

■ Takahashi H, Takahashi M, Nagaya H, Hirako M, Sawai K, Minamihashi A, Inumaru S, Yokomizo Y, Geshi M, Okano A, Okuda K: Establishment of a specific radioimmunoassay for bovine interferon tau. Theriogenology, 63, 1050-1060 (2005)

■ Skarzynski DJ, Jaroszewski JJ, Okuda K: Role of tumor necrosis factor-α and nitric oxide in luteolysis in cattle. Domest Anim Endocrinol, 29, 340-346 (2005)

2004年


Okuda K, Kasahara Y, Murakami S, Takahashi H, Woclawek-Potocka I, Skarzynski DJ: Interferon-τ blocks the stimulatory effect of tumor necrosis factor-α on prostaglandin F2α synthesis by bovine endometrial stromal cells.
Biol Reprod, 70 (1): 191-197 (2004)

Nishimura R, Bowolaksono A, Acosta TJ, Murakami S, Piotrowska K, Skarzynski DJ and Okuda K: Possible role of interleukin-1 in the regulation of bovine corpus luteum throughout the luteal phase.
Biol Reprod, 71 (5): 1688-1693 (2004)

Okuda K, Korzekwa A, Shibaya M, Murakami S, Nishimura R, Tsubouchi M, Woclawek-Potocka I, Skarzynski DJ: Progesterone is a suppressor of apoptosis in bovine luteal cells.
Biol Reprod, 71 (6): 2065-2071 (2004)

Nishimura R, Shibaya M, Skarzynski DJ, Okuda K: Progesterone stimulation by LH involves the phospholipase-C pathway in bovine luteal cells.
J Reprod Dev, 50 (2): 257-261 (2004)

Woclawek-Potocka I, Deptulak AK, Bah MM, Lee HY, Okuda K, Skarzynski DJ: Effects of nitric oxide and tumor necrosis factor-α on production of prostaglandin F2α and E2 in bovine endometrial cells.
J Reprod Dev, 50 (3): 333-340 (2004)

Korzekwa A, Jaroszewski JJ, Bogacki M, Deptula KM, Maslanka TS, Acosta TJ, Okuda K, Skarzynski DJ: Effects of prostaglandin F2α and nitric oxide on the secretory function of the bovine luteal cells.
J Reprod Dev, 50 (4): 411-417 (2004)

Sakumoto R, Okuda K: Possible actions of tumor necrosis factor-α in ovarian function.
J Reprod Dev, 50(1): 39-46 (2004)

Acosta TJ, Miyamoto A: Vascular control of ovarian function: ovulation corpus luteum formation and regression.
Anim Reprod Sci, 82, 127-140 (2004)

■ 奥田潔、作本亮介:黄体の寿命 -動物種によって異なる黄体退行のメカニズム-. 「家畜診療」51 (12), 717-728 (2004)

2003年

Nakano S, Kishi H, Ogawa H, Yasue H, Okano A and Okuda K: Trophinin is expressed in the porcine endometrium during the estrous cycle.
J Reprod Dev, 49 (2): 127-134, (2003)

■ Takahashi M, Takahashi H, Hamano S, Watanabe S, Inumaru S, Geshi M, Okuda K, Yokomizo Y, Okano A: Possible role of interferon-τ on in vitro development of bovine embryos.
J Reprod Dev, 49 (4): 297-305 (2003)

Takahashi H, Inumaru S, Takahashi M, Watanabe S, Iga K, Yokomizo Y, Geshi M, Okano A, Okuda K: Biological activity of recombinant bovine interferon-τ using an Autographica californica nuclear polyhedrosis baculovirus expression system.
J Reprod Dev, 49 (6): 433-440 (2003)

Skarzynski DJ, Bah MM, Deptula KM, Woclawek-Potocka I, Korzekwa A, Pilawski W, Okuda K: Roles of tumor necrosis factor-alpha of the estrous cycle in cattle: an in vivo study.
Biol Reprod, 69 (6): 1907-1913 (2003)

Sakumoto R, Shibaya M, Okuda K: Tumor necrosis factor-α (TNF) inhibits progesterone and estradiol-17β production from cultured granulosa cells: Presence of TNF receptors in bovine granulosa and theca cells.
J Reprod Dev, 49 (6): 441-449 (2003)

Okuda K, Sakumoto R: Multiple roles of TNF super family members in corpus luteum function.
Reprod Biol Endocrinol, 1 (1): 95 (2003)