岡山大学大学院 医歯薬学総合研究科 病理学 腫瘍病理第二病理|Department of Pathology Okayama University

Research achievements 業 績

2001年

原著論文

Hayashi K, Ohara N, Teramoto N, Onoda S, Chen HL, Oka T, Kondo E,Yoshino T, Takahashi K, Yates J and Akagi T:An animal model for human EBV-associated hemophagocytic syndrome (HPS) -- Herpesvirus papio frequently induces fatal lymphoproliferative disorders with HPS in rabbits--. Am J Pathol (2001) 158, 1533-1542.

Yamatomo T, Okano M, Ono T, Nakayama E, Yoshino T, Satoskar AR, Harn DA Jr and Nishizaki K:Sex-related differences in the initiation of allergic rhinitis in mice. Allergy (2001) 56, 525-531.

Hiraki A, Ikeda K, Yoshino T, Kaneshige T, Kiura K, Kunisada T, Fujiwara K, Tanimoto M and Harada M:Tumor-specific cytotoxic T lymphocyte responses against chondrosarcoma with HLA haplotype loss restricted by the remaining HLA class I allele. Biochem Biophys Res Commun (2001) 286, 786-791.

Asagoe K, Takahashi K, Yoshino T, Kondo E, Tanaka R, Arata J and Akagi T:Numerical, morphological and phenotypic changes in Langerhans cells in the course of murine graft-versus-host disease. Br J Dermatol (2001) 145, 918-927.

Uno M, Tsuchiyama J, Moriwaki A, Noguchi T, Mizoguchi K, Ogino T, Yoshino T, Okada S and Harada M:In vitro induction of apoptosis for nasal angiocentric natural killer cell lymphoma-derived cell line, NK-YS, by etoposide and cyclosporine A. Br J Haematol (2001) 113, 1009-1014.

Noguchi T, Ikeda K, Yamamoto K, Yoshida I, Ashiba A, Tsuchiyama J, Shinagawa K, Yoshino T, Takata M and Harada M:Antisense oligodeoxynucleotides to latent membrane protein 1 induce growth inhibition,
apoptosis and Bcl-2 suppression in Epstein-Barr virus (EBV)-transformed B-lymphoblastoid cells, but not in EBV-positive natural killer cell lymphoma cells. Br J Haematol (2001)114, 84-92.

Yonezumi M, Suzuki R, Suzuki H, Yoshino T, Oshima K, Hosokawa Y, Asaka M, Morishima Y, Nakamura S and Seto M:Detection of AP12-MALT1 chimaeric gene in extranodal and nodal marginal zone B-cell lymphoma by reverse transcription polymerase chain reaction (PCR) and genomic long and accurate PCR analyses. Br J Haematol (2001) 115, 588-594.

Chen L, Matsubara N, Yoshino T, Nagasaka T, Hoshizima N, Shirakawa Y, Naomoto Y, Isozaki H, Riabowol K and Tanaka N :Genetic alterations of candidate tumor suppressor ING1 in human esophageal squamous cell cancer. Cancer Res (2001) 61, 4345-4349.

Kambara T, Matsubara N, Nakagawa H, Notohara K, Nagasaka T, Yoshino T, Isozaki H, Sharp GB, Shimizu K, Jass J and Tanaka N:High frequency of low-level microsatellite instability in early colorectal cancer. Cancer Res (2001) 61, 7743-7746.

Yoshida A, Kohka TH, Nishibori M, Iwagaki H, Yoshino T, Morichika T, Yokoyama M, Kondo E, Akagi T and Tanaka N:IL-18-induced expression of intercellular adhesion molecule-1 in human monocytes --Involvement in IL-12 and IFN-Y production in PBMC--. Cell Immunol (2001) 210, 106-115.

Hattori H, Okano M, Yoshino T, Akagi T, Nakayama E, Saito C, Satoskar AR, Ogawa T, Azuma M and Nishizaki K:Expression of costimulatory CD80/CD86-CD28/CD152 molecules in nasal mucosa of patients with perennial allergic rhinitis. Clin Exp Allergy (2001) 31,1242-1249.

Okano M, Kino K, Takishita T, Hattori H, Ogawa T, Yoshino T, Yokoyama M and Nishizaki K:Roles of carbohydrates on Cry J 1, the major allergen of Japanese ceder pollen, is specific T-cell responses. J Allergy Clin Immunol (2001) 108, 101-108.

Takahashi K, Asagoe K, Teramoto N, Kondo E, Oka T, Hayashi K, Yoshino T and Akagi T:Morphological Interactions of Interdigitating dendritic cells with B and T cells in human mesenteric lymph nodes. Am J Pathol (2001) 159,131-138.

Oka T, Yoshino T, Hayashi K, Ohara N, Nakanishi T, Yamaai Y, Hiraki A, Sogawa CA, Kondo E, Teramoto N, Takahashi K, Tsuchiyama J and Akagi T:Reduction of hematopoietic cell-specific tyrosine phosphatase SHP-1 gene expression in natural killer cell lymphoma and various types of lymphomas/leukemias -- Combination analysis with cDNA expression array and tissue microarray --. Am J Pathol (2001) 159, 1495- 1505.

Okano M, Azuma M, Yoshino T, Hattori H, Nakada M, Satoskar AR, Harn DA Jr, Nakayama E, Akagi T and Nishizaki K:Differential role of CD80 and CD86 molecules in the induction and the effector phases of allergic rhinitis in mice. Am J Respir Crit Care Med (2001) 164, 1501-1507.

Kobashi K, Iwagaki H, Yoshino T, Morimoto Y, Kohka H, Kodama M, Nishibori M, Akagi T and Tanaka N:Down -regulation of IL-18 recepor in cancer patients --its clinical significance--. Anticancer Res (2001) 21, 3285-3294.

Mannami T, Yoshino T, Oshima K, Takase S, Kondo E, Ohara N, Nakagawa H, Ohtsuki H, Harada M and Akagi T:Clinical, histopathological, and immunogenetic analysis of ocular adnexal lymphoproliferative disorders. -- characterization of MALT lymphoma and reactive lymphoid hyperplasia--. Mod Pathol (2001) 14, 641-649.

Liu YX, Yoshino T, Ohara N, Oka T, Jin ZS, Hayashi K and Akagi T:Loss of expression of α4β7 integrin and L-selectin is associated with high-grade progression of low-grade MALT lymphoma. Mod Pathol (2001) 14,798-805.

Nitta Y, Nishibori M, Iwagaki H, Yoshino T, Mori S, Sawada K, Nakaya N, Saeki K and Tanaka N:Changes in serotonin dynamics in the gastrointestinal tract of colon-26 tumour-bearing mice -- Effects of cisplatin treatment--. Naunyn Schmiedebergs ArchPharmacol (2001) 364, 329-334.

症例報告

Fukunaga J, Mizukawa N, Ueno T, Takagi S, Yoshino T and Sugahara T:A case of Hodgkin's disease at submental region.Asian J Oral Maxillofac Surg (2001) 13, 79-82.

Fujii N, Takenaka K, Shinagawa K, Ikeda K, Maeda Y, Sunami K, Hiramatsu Y, Matsuo K, Ishimaru F, Niiya K, Yoshino T, Hirabayashi N and Harada M:Hepatic graft-versus-host disease presenting as an acute hepatitis after allogeneic peripheral blood stem cell transplantation. Bone Marrow Transpl (2001)27, 1007-1010.

Yoshino T, Ichimura K, Mannami T, Takase S, Ohara N, Okada H and Akagi T:Multiple organ mucosa- associated lymphoid tissue lymphomas often involve the intestine. Cancer (2001) 91, 346-353.

Miyata A, Kojima K, Yoshino T, Fujii S, Shinagawa K and Ichimura K :Concurrent Hodgkin's disease (mixed cellularity type) and T-cell chronic lymphocytic leukemia/prolymphocytic leukemia. Int J Hematol (2001) 73, 230-235.

Noguchi T, Ikeda K, Yamamoto K, Ashiba A, Yoshida J, Munemasa M, Takenaka K, Shinagawa K, Ishimaru F, Yoshino T, Niiya K and Harada M :Severe bleeding tendency caused by leukemic infiltration and destruction of vascular walls in chronic neutrophilic leukemia. Int J Hematol (2001) 74, 437-441.

Nakao A, Kobayashi E, Shen SD, Yoshino T and Tanaka N:Impact of tacrolimus and bone marrow augmentation on intestinal allograft survival and intragraft cytokine expression in rats. J Med (2001) 32, 207-230.

Katayama H, Takeuchi M, Yoshino T, Munemasa M, Tada A, Soda R and Takahashi K :Epstein-Barr virus associated diffuse large B-cell lymphoma complicated by autoimmune hemolytic anemia and pure red cell aplasia. Leuk Lymphoma (2001) 42, 539-542.

Kawahara K, Niguma T, Yoshino T, Omonishi K, Hatakeyama S, Nakamura S, Hirota S and Motoi M:Gastric carcinoma with psammomatous calcification after Billroth II reconstruction -- Case report and literature review --. Pathol Int (2001) 51,718-722.

総説

Nakanishi T, Oka T and Akagi T:On recent advances in DNA microarrays. Acta Med Okayama (2001) 55, 319- 328 .

Fukayama M, Yoshino T and Nakamura S:Pathology in Germany and Finland --a brief report of the delegates of the Japanese society of pathology--. Pathol Int (2001) 51, 221-225.

和文著作

症例報告

Tari A, Asaoku H, Tani H, Kashiwado K, Kurihara K, Fujihara M and Yoshino T:Evaluation of non-surgical therapy for the malignant lymphomas located mainly in stomach and duodenum.
日本消化器病学会雑誌(2001) 98, 1154-1163.

藤原久美、藤原恒太郎、土井省哲、村上史高、近藤由美雄、佐藤恭子、浜崎周次、田口孝爾、吉野 正、赤木忠厚:遺伝子診断された突然死Marfan症候群の一剖検例.
岡山外科病理雑誌(2001) 38,23-29.

高田晋一、近藤英作、赤木制二、林 一彦、二部野肇、小沢秀夫:Rhabdoid featureを伴った renal cell carcinomaの一例.
岡山外科病理雑誌 (2001) 38, 34-35.

満永幹雄,内田發三、長尾俊彦、内海義己、前川純子,木下敦恵、橋本和生、古正智道、杉山誠子、林一彦:両側上腕皮下にtumoral calcinosis をきたし、左心室にcalcified amorphous tumorを併発していた透析患者の1例 透析会誌 (2001) 34, 1427-1433.

芦立 久、坪井雅弘、林 一彦:Intravascular lymphomatosisの1例- 化学療法の治療経験.
脳神経外科 (2001) 29, 659-665.

鈴木孝章、林 一彦:手術時の組織捺印標本にて診断し得た肺放線菌症の1例.
臨床細胞診 (2001)40, 276-280.

清水敏成、河野玲華、松尾俊彦、大月 洋、品川克至、藤原隆行、吉野 正:両涙腺、両眼外筋肥大がみられた悪性リンパ腫の1例.
眼紀(2001)52, 672-675.

宮田 明、吉野 正、小島研介、藤井総一郎、菊池武志:胃のdiffuse large B-cell lymphomaを合併したT-cell prolymphocytic leukemia 臨床血液 (2001)42, 47-50.

総説

赤木忠厚:MALTリンパ腫とHelicobacter pyloriー炎症と腫瘍の接点ー.
病理と臨床 (2001) 19, 849-855.

吉野 正、赤木忠厚:胃MALTリンパ腫 ー基礎ー.
岡山医学会雑誌 (2001) 113, 87-91.

大原信哉、林 一彦、寺本典弘、吉野 正、赤木忠厚:ホジキンリンパ腫とEBウイルス.
血液・腫瘍科 (2001)43,259-264.

吉野 正、赤木忠厚:低悪性度B細胞性リンパ腫の病理.
血液フロンティア (2001)11,137-147.

吉野 正、赤木忠厚:低悪性度B細胞性リンパ腫の主な疾患単位と鑑別診断.
血液腫瘍科 (2001) 42, 325-332.

岡田裕之、水野元夫、辻 孝夫、吉野 正、横田憲治:胃MALTリンパ腫-手術をしない治療法-.
治療 (2001) 83, 138-140.

吉野 正、赤木忠厚:悪性リンパ腫ー診断と治療の進歩ーI.診断のための基本的事項 4.免疫組織学的検査の進歩と適用.日本内科学会雑誌 (2001)  90, 964-970.

横田憲治、綾田 潔、石井栄子、山崎理恵、小林計太、吉野 正、林 俊治、平井義一、赤木忠厚、小熊恵二:H.pylori感染と胃粘膜免疫応答.
日本臨床(2001)59, 342-348.

近藤英作、芝崎太:Bcl-2のアポトーシス阻止機構.
臨床免疫 (2001) 36, 832-836.

吉野 正:悪性リンパ腫、老人の悪性リンパ腫について.
老年病診療Q&A (2001) 35, 74-75.

単行本:吉野 正:悪性リンパ腫治療の新たなアプローチ 平野、菊池、飛内、倉石, 先端医学社 東京 (2001) 38-43.