岡山大学大学院 医歯薬学総合研究科 病理学 腫瘍病理第二病理|Department of Pathology Okayama University

Research achievements 業 績

2003年

原著論文

Yamaguchi M, Seto M, Okamoto M, Ichinohasama R, Nakamura N, Yoshino T, Suzumiya J, Murase T, Miura I, Akasaka T, Tamaru Ji J, Suzuki R, Kagami Y, Hirano M, Morishima Y, Ueda R, Shiku H and Nakamura S:De novo CD5(+) diffuse large B-cell lymphoma:a clinicopathologic study of 109 patients. Blood (2002) 99, 815-821.

Moriyama H, Matsubara N, Kanbara T, Mori M, Matsuoka J, Yoshino T, Takakura N, Shimizu K and Takaka N:Allelic imbalance and microsatellite instability in plasma DNA released from polyclonal pancreatic adenocarcinoma. Int J Oncol (2002) 21, 949-956.

Yamashita Y, Okano M, Yoshino T, Hattori H, Yamamoto T, Watanabe T, Takishita T, Akagi T and Nishizaki K:Carbohydrates expressed on Aspergillus fumigatus induce in vivo allergic Th2-type response. Clin Exp Allergy (2002) 32, 776-782.

Kawai H, Kiura K, Tabata M, Yoshino T, Takata I, Hiraki A, Chikamori K, Ueoka H, Tanimoto M, Harada M:Characterization of non-small-cell lung cancer cell lines established before and after chemotherapy. Lung Cance (2002) 35, 305-314.

Takase SS, Yoshino T, Mannami T, Munemasa M, Ichimura K, Okada H, Mizuno M, Tanimoto M, Harada M and Akagi T:Correlation between histological evaluation and PCR-based clonality analysis of gastric MALT lymphomas treated by eradication of Helicobacter pylori. J Clin Exp Hematopathol (2002) 42, 61-66.

Itoh H, Takahashi HK, Iwagaki H, Yoshino T, Morimoto Y, Saito S, Yagi T, Akagi T, Nishibori M and Tanaka N :Effect of histamine on intercellular adhesion molecule-1 expression and production of interferon-yand interleukin-12 in mixed lymphocyte reaction stimulated with interleukin-18. Transplantation (2002) 74, 864-870.

Yoshida A, Takahashi HK, Iwagaki H, Yoshino T, Morichika T, Yokoyama M, Itoh H, Mori S, Akagi T, Nishibori M and Tanaka N :Essential role of ICAM-1/LFA-1 interaction in synergistic effect of IL-18 and IL-12on IFN-γproduction in human PBMC. Naunyn Schmiedeberg's Arch Pharmacol (2002) 365, 181-186.

Yoshino T, Nakamura S, Suzumiya J, Niitsu N, Ohshima K, Tsuchiyama J, Shinagawa K, Tanimoto M, Sadahira Y, Harada M, Kikuchi M and Akagi T:Expression of cutaneous lymphocyte antigen is associated with a poor outcome of nasal-type natural killer-cell lymphoma. Br J Haematol (2002) 118, 482-487.

Jin HS, Yoshino T, Jin Z, Oka T, Kobayashi K, Yamasaki R, Liu YX, Yokota K, Oguma K and Akagi T:Expression of heat shock protein 60 in normal and neoplastic human lymphoid tissues. J Clin Exp Hematopathol (2002) 42, 25-32.

Takahashi Hk, Yoshida A, Iwagaki H, Yoshino T, Itoh H,Morichika T, Yokoyama M, Akagi T, Tanaka N, Mori S, and Nishibori M:Histamine regulation of interleukin-18-initiating cytokine cascade is associated with down-regulation of intercellular adhesion molecule-1 expression in human peripheral blood mononuclear cells. Pharmacol Expl Therap (2002) 300, 227-235.

Tsuchiyama J, Yoshino T, Toba K, Harada N, Nishiuchi R, Akagi T, Furukawa T, Takahashi M, Fuse I, Aizawa Y and Harada M:Induction and characterization of cutaneous lymphocyte antigen on natural killer cells. Br J Haematol (2002) 118, 654-662.

Hattori H, Okano M, Yamamoto T, Yoshino T, Yamashita Y, Watanabe T, Satoskar AR, Harn DA and Nishizaki K:Intranasal application of purified protein derivative suppresses the initiation but not the exacerbation of allergic rhinitis in mice. Clin Exp Allergy (2002) 32, 951-959.

Saito T, Shinagawa K, Takenaka K, Matsuo K, Yoshino T, Kiura K, Niiya K and Harada M:Ocular manifestation of acute graft-versus-host disease after allogeneic peripheral blood stem cell transplantation. Int J Hematol (2002) 75, 332-334.

Inagaki H, Chan JK, Ng JW, Okabe M, Yoshino T, Okamoto M, Ogawa H, Matsushita H, Yokose T, Matsuno Y, Nakamura N, Nagasaka T, Ueda R, Eimoto T and Nakamura S:Primary thymic extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue type exhibits distinctive clinicopathological and molecular features. Am J Pathol (2002) 160, 1435-1443.

Takahashi HK, Iwagaki H, Yoshino T, Mori S, Morichika T, Itoh H, Yokoyama M, Kubo S, Kondo E, Akagi T, Tanaka N and Nishibori M:Prostaglandin E2 inhibits IL-18-induced ICAM-1 and B7.2 expression through EP2/EP4 receptors in human peripheral blood mononuclear cells. J Immunol (2002) 168, 4446-4454.

Niitsu N, Okamato M, Nakamine H, Yoshino T, Tamaru J, Nakamura S, Higashihara M and Hirano M:Simultaneous elevation of the serum concentrations of vascular endothelial growth factor and interleukin-6 as independent predictors of prognosis in aggressive non-Hodgkin's lymphoma. Eur J Haematol (2002) 68, 91-100.

Ota S, Shinagawa K, Ueoka H, Tada S, Tabata M, Hamazaki S, Kondo E, Kiura K, Mannami T, Shibayama T, Niiya K and Harada M:Spontaneous regression of metastatic endometrial stromal sarcoma. Jpn J Clin Oncol (2002) 32 71-74.

Oka T, Ouchida M, Koyama M, Ogama Y, Takada S, Nakatani Y, Tanaka T, Yoshino T, Hayashi K, Ohara N, Kondo E, Takahashi K, Tsuchiyama J, Tanimoto M, Shimizu K and Akagi T:Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas. Cancer Res (2002) 62, 6390-6394.

Nakamura N, Nakamine H, Tamaru J, Nakamura S, Yoshino T, Ohshima K and Abe M:The distinction between burkitt lymphoma and diffuse large B-Cell lymphoma with c-myc rearrangement. Mod Pathol (2002) 15, 771-776.

症例報告

Uesugi T, Uno S and Hayashi K:Colonic adenocarcinoma associated withdysplastic lesions in an Indiana pouch. J of Urology (2002) 168, 2117.

Maeda Y, Fujiwara N, Yoshino T, Kiura K, Ueoka H and Harada M:Extragonadal germ cell tumor with high serum levels of du-pan-2. J Urol (2002) 167, 246-247.

Okada S, Wada J, Tsukinoki T, Hirano N, Watanabe Y, Shikata K, Yamasaki Y, Takase SS, Yoshino T, Akagi T and Makino H :Angiocentric immunoproliferative lesions of the lung associated with diffuse renal involvement. Am J Kidney Dis (2002) 39, 1-6.

Namba N, Hiraki A, Tabata M, Kiura K, Ueoka H, Yoshino T and Tanimoto M:Axillary metastasis as the first manifectation of occult breast cancer in a man --A case report--. Anticancer Res (2002) 22, 3611-3614.

Kojima K, Kurokawa MS, Tanimoto K, Kojima Y, Hara M, Yoshino T, Harada M, Tanimoto M, Nishioka K and Kato T:Clonal expansion of limited T cell clonotypes in affected muscle from a patient with post-transplant polymyositis. Bone Marrow Transplant (2002) 30, 467-470.

Tsuchiyama J, Imajo K, Yoshino T, Nanba N, Toyota A, Yoshida C, Fujii K, Kondo E, Okazuka K, Hashimoto S, Toba K, Fuse I, Aizawa Y, Harada M and Tsubota T:High-dose chemotherapy and autologous peripheral blood stem cell transplantation for treatment of unspecified peripheral T-cell lymphoma presented with hepatosplenomegaly and hypercytokinemia syndrome-- Report of three cases--. Ann Hematol (2002) 81, 588-592.

Yanai H, Matsuura H, Kawasaki M, Takada Y, Tabuchi Y, Yoshino T:Immature teratoma of the ovary with a minor rhabdomyosarcomatous component and fatal rhabdomyosarcomatous metastases --The first case in a child--. Int J Gynecol Pathol (2002) 21, 82-85.

Tsuchiyama J, Yoshino T, Imajo K, Kondou E, Hamada E, Tomiyama Y, Toba K, Furukawa T, Fuse I, Aizawa Y, Harada M and Tsubota T:Lymphomatous polyp of mantle cell type in the duodenum complicated by gastric cancer --A case of trisomy 3 and t(11;14)(q13;q32)--. Ann Hematol (2002) 81, 224-227.

Yoshino T, Yamadori I, Hasuo T, Oue H, Kunitomo T, Takase S, Hayashi K, Sadahira Y and Akagi T:Primary gastric T-cell lymphoma associated with human T-cell leukemia virus type I shows 'lymphoepithelial lesions' . J Clin Exp Hematopathol (2002) 42, 39-42.

Hiraki A, Ueoka H, Yoshino T, Tabata M, Kiura K, Tanimoto Y, Kamao T, Komoto R and Harada M:Primary signet-ring cell carcinoma of the lung with histochemical characterization. Anticancer Res (2002) 22, 1079-1081.

Makita M, Maeda Y, Takenaka K, Shinagawa K, Sunami K, Hiramatsu Y, Fujii N, Ishimaru F, Ikeda K, Niiya K, Yoshino T and Harada M:Successful treatment of progressive NK cell lymphoma with allogeneic peripheral stem cell transplantation followed by early cyclosporine tapering and donor leukocyte infusions. Int J Hematol (2002) 76, 94-97.

Kozuka T, Kiura K, Katayama H, Fujii N, Ishimaru F, Ikeda K, Ueoka H, Hamasaki S, Yoshino T, Kashihara Y, Date H, Tanimoto M and Harada M:Tandem high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation for recurrent soft tissue sarcoma. Anticancer Res (2002) 22, 2939-2944.

Ito W, Kojima K, Fujiwara K, Nanba Y, Yoshino T, Shinagawa K, Ishimaru F, Ikeda K, Niiya K and Tanimoto M:Thymic epithelidal hyperplasiawith nodular sclerosis Hodgkin's disease. Leuk Lymph (2002) 43, 2229-2231.

総説

Hayashi K, N.Teramoto and Akagi T:Animal in vivo models of Epstein-Barr virus-related disease -- Special Reference to Rabbit Models--. Histol Histopathol (2002) 17, 1293-1310.

単行本(著書)

Hayashi K, Jin Z and Akagi T:Rabbit model for EBV-associated fatal lymphoproliferative disorders with hemophagocytosis. Res Adv in Virology 2 . Mohan ed, Global Research Network, (2002) pp1-12.

和文著作

症例報告

武田靖志、小川晃弘、赤木博文、結縁晃治、西崎和則、服部 央、赤木成子、吉野 正:喉頭・気管に発生した髄外性形質細胞腫の1例. 耳鼻咽喉科・頭頸部外科 (2002) 74, 383-387.

武田靖志、赤木博文、小川晃弘、結縁晃治、西崎和則、山下安彦、岡本 伸、吉野 正:耳下腺木村病に再発を繰り返す口腔・喉頭好酸球浸潤性肉芽を認めた1例. 耳鼻咽喉科・頭頸部外科 (2002) 74, 439-442.

総説

岡 剛史、吉野 正、林 一彦、赤木忠厚 :悪性リンパ腫・白血病におけるプロテインチロシンフォスファターゼSHP1遺伝子の発現異常.  癌の臨床 (2002) 48, 561-568.

吉野 正、赤木忠厚:Marginal zone lymphoma --Marginal zoneリンパ球の位置づけとリンパ腫--. 医学のあゆみ (2002) 200, 1032.

吉野 正、赤木忠厚:非ホジキンリンパ腫の診断と治療 1.病理分類の現状と問題点. 血液フロンティア (2002) 12, 1553-1561.

岡 剛史、吉野 正、林 一彦、赤木忠厚:悪性リンパ腫・白血病におけるプロテインチロシンフォスファターゼSHP1遺伝子の発現異常. 癌の臨床 (2002) 48, 561-568.

赤木忠厚、吉野 正:悪性リンパ腫の病理診断. 診断病理 (2002) 19, 179-188.

吉野 正、赤木忠厚:悪性リンパ腫の病理分類. 現代医療 (2002) 34, 2819-2824.

吉野 正、赤木忠厚:非ホジキンリンパ腫の診断と治療 1.病理分類の現状と問題点. 血液フロンティア (2002) 12, 1553-1561. 単行本(著書)

吉野 正、赤木忠厚:リンパ節・脾・胸腺. 「病理組織の見方と鑑別診断」第4版. 赤木、大朏、松原編, 医歯薬出版, 東京 (2002) p 61-89.

報告書

岡 剛史:悪性リンパ腫発症機構に関与する遺伝子群の分子病理学的解析. 平成12-14年度科学研究費補助金(基盤研究C)成果報告書

その他

井藤久雄、岡崎悦夫、日合 弘、赤木忠厚、森 茂郎:病理検体の目的外使用のガイドライン. Medical Technology (2002) 30,