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Okayama University Medical Research Updates (OU-MRU)Vol.86

January 22, 2021

Source: Okayama University (JAPAN), Public Relations Division
For immediate release: 22 January 2021
Okayama University research: Plates and belts — a toolkit to prevent accidental falls during invasive vascular procedures

(Okayama, 19 January) In a study reported in Acta Medica Okayama, researchers at Okayama University describe an innovative plate that confines patients to their beds while undergoing vascular procedures thereby preventing unforeseen falls

Patients undergoing hemodialysis (which requires the regular withdrawal of blood) often need to undergo interventional procedures that keep the blood vessels of the forearm dilated. Percutaneous transluminal angioplasty (PTA), the most common of these procedures, requires a surgeon to visualize microvessels within the arm using an X-ray while the patient lays supine on a motorized bed. Unfortunately, a complication that arises during PTA is the enhanced risk of falls from these elevated beds. Now, Assistant Professor OHARA Toshiaki from Okayama University and colleagues have developed a simple plate-like contraption which secures patients firmly onto their bed while providing the surgeon adequate space for the procedure.

The vascular-access intervention assistance plate—as the innovators named it—is constructed from a durable and cost-effective polymer called polypropylene. The plate is structured to fit under the bed mattress, with a slit for inserting a thick belt that firmly tethers the patient to the bed, at the waist. Additionally, the plate has a lateral protrusion to accommodate and fasten the patient’s arm using a strap. Adjacent to this, a space for placing surgical tools is also provided.

To first calculate the strength of this contraption, plates of varying thickness were simulated to hold loads representative of standard patient weights. The penetration of X-rays through the plates was also verified to confirm that the polymeric material does not interfere with the imaging. Based on the simulations, the thickness of the plate was set at 7 millimeters. The team then looked at real-life patient data to check the device’s effectiveness.

Two groups of patients with similar profiles undergoing angioplasties were analyzed: one group that underwent PTAs without the plate (401 patients) and one with the plate (683 patients). Indeed, the former group had three patients fall, while the latter had none. The researchers also found that signs of dementia, a common cause of accidents and falls, were similar between the two groups. The incidence of falls was thus attributable to the set-up of the procedure and in fact preventable after securing patients to their beds with the plate.

“The vascular-access intervention assistance plate provides good operability and safety, preventing accidental falls in patients undergoing hemodialysis or other procedures,” summarizes the research team. Containing accidental falls is key to preventing further complications in patients undergoing hemodialysis, who are often severely ill and/or old. Introducing the plate into procedures can also enable minimal monitoring of the patient thereby allow medical staff to concentrate primarily on the surgery.

Background
Hemodialysis and angioplasties: Hemodialysis is a procedure that patients with kidney failure undergo wherein blood is drawn from the forearm and cleared of toxins outside the body. Given the frequency and invasiveness of this procedure, blood vessels at the site of withdrawal often start constricting and make the process difficult. Thus, intrusive procedures such as percutaneous transluminal angioplasties or the introduction of a stent are usually performed which help dilate such blood vessels.

An X-ray is employed to locate the site of constriction with precision. However, this makes the procedure cumbersome and requires minimal movement from the patient. Ancillary tools such as the vascular-access intervention assistance plate are, therefore, warranted to reduce unwanted complications like falls and aid with stillness during the procedure.


Movie(YouTube)
New fall prevention plate for vascular access surgery (3min38sec)
New fall prevention plate for X-ray fluoroscopic cardiac catheterization (3min55sec)

Reference
Toshiaki Ohara, Kazufumi Sakurama, Satoshi Hiramatsu. New Vascular-Access Intervention Assistance Plate Provides Good Operability and Safety by Preventing Accidental Falls:First Experience of 1,872 Cases. Acta Medica Okayama, 2020, Vol.74, No.6, pp.505-511.
DOI : http://doi.org/10.18926/AMO/60880
New Vascular-Access Intervention Assistance Plate Provides Good Operability and Safety by Preventing Accidental Falls: First Experience of 1,872 Cases - Acta Medica Okayama


Reference (Okayama University e-Bulletin & OU-MRU) : Assistant Professor OHARA’s team
OU-MRU Vol.22:Medical supportive device for hemodialysis catheter puncture
OU-MRU Vol.50:Iron removal as a potential cancer therapy
OU-MRU Vol.56:New device for assisting accurate hemodialysis catheter placement


Correspondence to
Assistant Professor OHARA Toshiaki, M.D., Ph.D.
Department of Pathology & Experimental Medicine,
Graduate School of Medicine, Dentistry and Pharmaceutical
Sciences, Okayama University, Shikata-cho 2-5-1, Okayama-city,
Okayama 700-8558, Japan
E-mail: t_ohara(a)cc.okayama-u.ac.jp
For inquiries, please contact us by replacing (a) with the @ mark.
Department of Pathology & Experimental Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences


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Okayama University Medical Research Updates (OU-MRU)
The whole volume : OU-MRU (1- )
Vol.1:Innovative non-invasive ‘liquid biopsy’ method to capture circulating tumor cells from blood samples for genetic testing
Vol.2:Ensuring a cool recovery from cardiac arrest
Vol.3:Organ regeneration research leaps forward
Vol.4:Cardiac mechanosensitive integrator
Vol.5:Cell injections get to the heart of congenital defects
Vol.6:Fourth key molecule identified in bone development
Vol.7:Anticancer virus solution provides an alternative to surgery
Vol.8:Light-responsive dye stimulates sight in genetically blind patients
Vol.9:Diabetes drug helps towards immunity against cancer
Vol.10:Enzyme-inhibitors treat drug-resistant epilepsy
Vol.11:Compound-protein combination shows promise for arthritis treatment
Vol.12:Molecular features of the circadian clock system in fruit flies
Vol.13:Peptide directs artificial tissue growth
Vol.14:Simplified boron compound may treat brain tumours
Vol.15:Metamaterial absorbers for infrared inspection technologies
Vol.16:Epigenetics research traces how crickets restore lost limbs
Vol.17:Cell research shows pathway for suppressing hepatitis B virus
Vol.18:Therapeutic protein targets liver disease
Vol.19:Study links signalling protein to osteoarthritis
Vol.20:Lack of enzyme promotes fatty liver disease in thin patients
Vol.21:Combined gene transduction and light therapy targets gastric cancer
Vol.22:Medical supportive device for hemodialysis catheter puncture
Vol.23:Development of low cost oral inactivated vaccines for dysentery
Vol.24:Sticky molecules to tackle obesity and diabetes
Vol.25:Self-administered aroma foot massage may reduce symptoms of anxiety
Vol.26:Protein for preventing heart failure
Vol.27:Keeping cells in shape to fight sepsis
Vol.28:Viral-based therapy for bone cancer
Vol.29:Photoreactive compound allows protein synthesis control with light
Vol.30:Cancer stem cells’ role in tumor growth revealed
Vol.31:Prevention of RNA virus replication
Vol.32:Enzyme target for slowing bladder cancer invasion
Vol.33:Attacking tumors from the inside
Vol.34:Novel mouse model for studying pancreatic cancer
Vol.35:Potential cause of Lafora disease revealed
Vol.36:Overloading of protein localization triggers cellular defects
Vol.37:Protein dosage compensation mechanism unravelled
Vol.38:Bioengineered tooth restoration in a large mammal
Vol.39:Successful test of retinal prosthesis implanted in rats
Vol.40:Antibodies prolong seizure latency in epileptic mice
Vol.41:Inorganic biomaterials for soft-tissue adhesion
Vol.42:Potential drug for treating chronic pain with few side effects
Vol.43:Potential origin of cancer-associated cells revealed
Vol.44:Protection from plant extracts
Vol.45:Link between biological-clock disturbance and brain dysfunction uncovered
Vol.46:New method for suppressing lung cancer oncogene
Vol.47:Candidate genes for eye misalignment identified
Vol.48:Nanotechnology-based approach to cancer virotherapy
Vol.49:Cell membrane as material for bone formation
Vol.50:Iron removal as a potential cancer therapy
Vol.51:Potential of 3D nanoenvironments for experimental cancer
Vol.52:A protein found on the surface of cells plays an integral role in tumor growth and sustenance
Vol.53:Successful implantation and testing of retinal prosthesis in monkey eyes with retinal degeneration
Vol.54:Measuring ion concentration in solutions for clinical and environmental research
Vol.55:Diabetic kidney disease: new biomarkers improve the prediction of the renal prognosis
Vol.56:New device for assisting accurate hemodialysis catheter placement
Vol.57:Possible link between excess chewing muscle activity and dental disease
Vol.58:Insights into mechanisms governing the resistance to the anti-cancer medication cetuximab
Vol.59:Role of commensal flora in periodontal immune response investigated
Vol.60:Role of commensal microbiota in bone remodeling
Vol.61:Mechanical stress affects normal bone development
Vol.62:3D tissue model offers insights into treating pancreatic cancer
Vol.63:Promising biomarker for vascular disease relapse revealed
Vol.64:Inflammation in the brain enhances the side-effects of hypnotic medication
Vol.65:Game changer: How do bacteria play Tag ?
Vol.66:Is too much protein a bad thing?
Vol.67:Technology to rapidly detect cancer markers for cancer diagnosis
Vol.68:Improving the diagnosis of pancreatic cancer
Vol.69:Early gastric cancer endoscopic diagnosis system using artificial intelligence
Vol.70:Prosthetics for Retinal Stimulation
Vol.71:The nervous system can contribute to breast cancer progression
Vol.72:Synthetic compound provides fast screening for potential drugs
Vol.73:Primary intraocular lymphoma does not always spread to the central nervous system
Vol.74:Rising from the ashes—dead brain cells can be regenerated after traumatic injury
Vol.75:More than just daily supplements — herbal medicines can treat stomach disorders
Vol.76:The molecular pathogenesis of muscular dystrophy-associated cardiomyopathy
Vol.77:Green leafy vegetables contain a compound which can fight cancer cells
Vol.78:Disrupting blood supply to tumors as a new strategy to treat oral cancer
Vol.79:Novel blood-based markers to detect Alzheimer’s disease
Vol.80:A novel 3D cell culture model sheds light on the mechanisms driving fibrosis in pancreatic cancer
Vol.81:Innovative method for determining carcinogenicity of chemicals using iPS cells
Vol.82:Making memories — the workings of a neuron revealed
Vol.83:Skipping a beat — a novel method to study heart attacks
Vol.84:Friend to Foe—When Harmless Bacteria Turn Toxic
Vol.85:Promising imaging method for the early detection of dental caries

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