1. Tsuzuki K, Kimura K, Fujii N, Yokosawa N, and Oguma K. The complete nucleotide sequence of the gene coding for the nontoxic-nonhemagglutinin component of Clostridium botulinum type C progenitor toxin. Biochem. Biophys. Res. Commun. 183: 1273-1279, 1992.
2. Fujii N, Kimura K, Yashiki T, Tsuzuki K, Moriishi K, Syuto B, Yokosawa N, and Oguma K. Cloning and whole nucleotide sequence of the gene for light chain component of botulinum type E toxin from Clostridium butyricum strain BL6340 and Clostridium botulinum type E strain Mashike. Microbiol. Immunol. 36: 213-220, 1992.
3. Fujii N, Kwon K, Yashiki T, Isogai E, Isogai H, Kimura K, and Oguma K. Oligo-2', 5'-adenylate synthetase activity in cells persistently infected with human T-cell leukemia virus (HTLV-1). Microbiol. Immunol. 36: 425-429, 1992.
4. Yokota K, Hayashi S, Fujii N, Yoshikawa K, Kotake S, Isogai E, Ohno S, and Oguma K. Antibody response to oral Streptococci in Behcet's disease. Microbiol. Immunol. 36: 815-822, 1992.
5. Fujii N, Kimura K, Yokosawa N, Tsuzuki K, and Oguma K. A zinc-protease specific domain in botulinum and tetanus neurotoxins. Toxicon. 30: 1486-1488, 1992.
6. Yokosawa N, Fujii N, Tsuzuki K, Kimura K, Syuto B, Moriishi K, and Oguma K. Inhibition of norepinephrine secretion from digitonin permeabilized PC12 cells by botulinum type D toxin. Toxicon. 30: 1555-1562, 1992.
7. Fujii N, Kimura K, Yokosawa N, Yashiki T, Tsuzuki K, and Oguma K. The complete nucleotide sequence of the gene encoding the nontoxic component of Clostridium botulinum type E progenitor toxin. J. Gen. Microbiol. 139: 79-86, 1993.
8. Hayashi S, Yokota K, Takizawa Y, Tomizawa I, Nejime T, and Oguma K. Development and evaluation of capture enzyme-linked immunosorbent assays for detection of immunoglobulin G and M antibodies to group A streptococcal antigens. Microbiol. Immunol. 37: 271-279, 1993.
9. Fujii N, Kimura K, Yokosawa N, Oguma K, Yashiki T, Takeshi K, Ohyama T, Isogai E, and Isogai H. Similarity in nucleotide sequence of the gene encoding nontoxic component of botulinum toxin produced by toxigenic Clostridium butyricum strain BL6340 and Clostridium botulinum type E strain Mashike. Microbiol. Immunol. 37: 395-398, 1993.
10. Ishii N, Isogai E, Yamakawa Y, Nakajima H, Ohno S, Isogai H, Hayashi S, Yokota K, and Oguma K. Demonstration of antigen-specific immune response against Streptococcus sanguis. J. Dermatol. Sci. 5: 182-189, 1993.
11. Moriishi K, Shuto B, Saito M, Oguma K, Fujii N, Abe N, and Naiki M. Two different types of ADP-ribosyltransferase C3 from Clostridium botulinum type D lysogenized organisms. Infect. Immun. 61: 5309-5314, 1993.
12. Yokosawa N, Suga K, Kimura K, Tsuzuki, K, Fujii N, Oguma K, and Yokosawa H. Exogenous zinc ion is required for inhibitory activity of botulinum neurotoxin C1 against norepinephrine release and its endopeptidase activity toward substance P. Biochem. Mol. Bio. Int. 32: 455-463, 1994.
13. Yokota K, Hirai Y, Haque M, Hayashi S, Isogai H, Sugiyama T, Nagamachi E, Tsukada Y, Fujii N, and Oguma K. Heat shock protein produced by Helicobacter pylori. Microbiol. Immunol. 38: 403-405, 1994.
14. Isogai H, Isogai E, Kimura K, Fujii N, Yokota K, and Oguma K. Helicobacter pylori induces inflammation in mouse urinary bladder and pelvis. Microbiol. Immunol. 38: 331-336, 1994.
15. Fujinaga Y, Inoue K, Shimazaki S, Tomochika K, Tsuzuki K, Fujii N, Watanabe T, Ohyama T, Inoue K, and Oguma K. Molecular construction of Clostridium botulinum type C progenitor toxin and its gene organization. Biochem. Biophys. Res. Commun. 205: 1291-1298, 1994.
16. Ohyama T, Watanabe T, Fujinaga Y, Inoue K, Sunagawa H, Fujii N, Inoue K, and Oguma K. Characterization of Nontoxic-nonhemagglutinin component of the two types of progenitor toxin (M and L) produced by Clostridium botulinum Type D CB-16. Microbiol. Immunol. 39: 457-465, 1995.
17. Yokota K, Hayashi S, Araki Y, Isogai E, Kotake S, Yoshikawa K, Fujii N, Hirai Y, and Oguma K. Characterization of Streptococcus sanguis isolated from patients with Behchet’s disease. Microbiol. Immunol. 39: 729-732, 1995.
18. Haque M, Hirai Y, Yokota K, and Oguma K. Lipid profiles of Helicobacter pylori and Helicobacter mustelae grown in serum-supplemented and serum-free media. Acta Med. Okayama. 49: 205-211, 1995.
19. Fujinaga Y, Takeshi K, Inoue K, Fujita R, Ohyama T, Moriishi K, and Oguma K. Type A and B neurotoxin genes in a Clostridium botulinum type AB strain. Biochem. Biophys. Res. Commun. 213: 737-745, 1995.
20. Hirai Y, Haque M, Yoshida T, Yokota K, Yasuda T, and Oguma K. Unique cholesteryl glucosides in Helicobacter pylori: composition and structural analysis. J. Bacteriol. 177: 5327-5333, 1995.
21. Haque M, Hirai Y, Yokota K, and Oguma K. Steryl glycosides: a characteristic feature of the Helicobacter spp.? J. Bacteriol. 177: 5334-5337, 1995.
22. Fujita R, Fujinaga Y, Inoue K, Nakajima H, Kumon H, and Oguma K. Molecular characterization of two forms of nontoxic-nonhemagglutinin components of Clostridium botulinum type A progenitor toxins. FEBS lett. 376: 41-44, 1995.
23. Takeshi K, Fujinaga Y, Inoue K, Nakajina H, Oguma K, Ueno T, Sunagawa H, and Ohyama T. Simple method for detection of Clostridium botulinum type A to F neurotoxin genes by polymerase chain reaction. Microbiol. Immunol. 40: 5-11, 1996.
24. Moriishi K, Koura M, Fujii N, Fujinaga Y, Inoue K, Syuto B, and Oguma K. Molecular cloning of the gene encoding the mosaic neurotoxin, composed of parts of botulinum neurotoxin types C1 and D, and PCR detection of this gene from Clostridium botulinum type C organisms. Appl. Environ. Microbiol. 62: 662-667, 1996.
25. Haque M, Hirai Y, Yokota K, Mori N, Israt J. Ito H, Hotta H, Yano I, Kanemasa Y, and Oguma K. Lipid profile of Helicobacter spp.: presence of cholesteryl glucoside as a characteristic feature. J. Bacteriol. 178: 2065-2070, 1996.
26. Inoue K, Fujinaga Y, Watanabe T, Ohyama T, Takeshi K, Moriishi K, Nakajima H, Inoue K, and Oguma K. Molecular composition of Clostridium botulinum type A progenitor toxins. Infect. Immun. 64: 1589-1594, 1996.
27. Moriishi K, Koura M, Abe N, Fujii N, Fujinaga Y, Inoue K, and Oguma K. Mosaic structures of neurotoxins produced from Clostridium botulinum type C and D organisms. Biochim. Biophis. Acta. 1307: 123-126, 1996.
28. Hayashi S, Sugiyama T, Hisano K, Awakawa T, Kurokawa I, Yachi A, Isogai H, Isogai E, Yokota K, Hirai Y, Oguma K, and Fujii N. Quantitative detection of secretory immunogloblin A to Helicobacter pylori in gastric juice: antibody capture enzyme-linked immunosorbent assay. J. Clin. Lab. Analysis. 10: 74-77, 1996.
29. Isogai H, Isogai E, Hayashi S, Kimura K, Kubota T, Fujii N, and Oguma K. Experimental Helicobacter pylori infection in association with other bacteria. Microbiol. Immunol. 41: 361-365, 1997.
30. Hayashi S, Sugiyama T, Yachi A, Yokota K, Hirai Y, Oguma K, and Fujii N. A rapid and simple mathod to quantify Helicobacter pylori adhesion to human gastric MKN-28 cells. J. Gastroen. Hepatol. 12: 373-375, 1997.
31. Fujinaga Y, Inoue K, Watanabe S, Yokota K, Hirai K, Nagamachi E, and Oguma K. The haemagglutinin of Clostridium botulinum type C progenitor toxin plays an essential role in binding of toxin to the epithelial cells of guinea pig small intestine, leading to the efficient absorption of the toxin. Microbiol. 143: 3841-3847, 1997.
32. Yokota K, and Oguma K. IgA protease produced by Streptococcus sanguis, and antibody production against IgA protease in the patients with Bechet`s disease. Microbiol. Immunol. 41: 925-931, 1997.
33. Hayashi S, Sugiyama T, Yachi A, Yokota K, Hirai Y, Oguma K, and Fujii N. Effect of ecabet sodium on Helicobacter pylori adhesion to gastric epithelial cells. J. Gastroen. 32: 593-597, 1997.
34. Takeshi K, Ikeda T, Kubo A, Fujinaga Y, Makino S, Oguma K, Isogai E, Yoshida S, Sunagawa H, Ohyama T, and Kimura H. Direct datection by PCR of Escherichia coli O157 and enteropathogens in patients with bloody diarrhea. Microbiol. Immunol. 41: 819-822, 1997.
35. Kobayashi K, Yokota K, Yoshino T, Kawahara Y, Day A, Hirai Y, Oguma K, and Akagi T. Detection of Helicobacter pylori associated antigen and heat shock protein 60 on follicular dendritic cells in the germinal centers of low grade B cell lymphoma of gastric mucosa associated lymphoid tissue (MALT). J. Clin. Pathol. 51: 396-398, 1998.
36. Dey A, Yokota K, Kobayashi K, Oguma K, Hirai Y, and Akagi T. Antibody and cytokine responses in Helicobacter pylori-infected various mouse strains. Acta Med. Okayama. 5: 41-48, 1998.
37. Hayashi S, Sugiyama T, Amano k, Isogai H, Isogai E, Aihara M, Kikuchi M, Asaka M, Yokota K, Oguma K, Fujii N, and Hirai Y. Effect of rebamipide, a novel antiulcer agent, on Helicobacter pylori adhesion to gastric epithelial cells. Antimicrob. Agents. Chemother. 42: 1895-1899, 1998.
38. Nakajima H, Inoue K, Ikeda T, Fujinaga Y, Sunagawa H, Takeshi K, Ohyama T, Watanabe T, Inoue K, and Oguma K. Molecular composition of the 16S toxin produced by a Clostridium botulinum type D strain, 1873. Microbiol. Immunol. 42: 599-605, 1998.
39. Marvaud, J. C, Gibert M, Inoue K, Fujinaga Y, Oguma K, and Popoff M. R. botR/A is a positive regulator of botulinum neurotoxin and associated non-toxin protein genes in Clostridium botulinum A. Mol. Microbiol. 29: 1009-1018, 1998.
40. Yokota K, Fujinaga Y, Inoue K, Seo G, Takeshi K, Nagamachi E, and Oguma K. Classification of Clostridium butyricum based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis and pulsed-field gel electrophoresis. Anaerobe. 4: 177-181, 1998.
41. Hayashi S, Sugiyama T, Yokota K, Isogai H, Isogai E, Oguma K, Asaka M, Fujii N, and Hirai Y. Analysis of immunoglobulin a antibodies to Helicobacter pylori in serum and gastric juice in relation to mucosal inflammation. Clin. Diagn. Lab. Immunol. 5: 617-621, 1998.
42. Sasaki M, Hattori Y, Tomita F, Moriishi K, Kanno M, Kohya T, Oguma K, and Kitabatake A. Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein-and rho protein-mediated Ca++ sensitization of smooth muscle rabbit mesenteric artery. Br. J. Pharmacol. 125: 1651-1660, 1998.
43. Hayashi S, Sugiyama T, Asaka M, Yokota K, Oguma K, and Hirai Y. Modification of Helicobacter pylori adhesion to human gastric epithelial cells by antiadhesion agents. Digest. Dis. Sci. 43: 56-60, 1998.
44. Kawahara Y, Yokota K, Mizuno M, Yunoki M, Uesu T, Okada H, Kobayashi K, Hirai Y, Oguma K, and Tsuji T. Antibodies to human gastric epithelial cells and heat shock protein60 in Helicobacter pylori positive mucosa associated lymphoid tissue lymphoma. Gut.
45: 20-23, 1999. 45. Yokota K, Kobayashi K, Kawahara Y, Hayashi S, Hirai Y, Mizuno M, Okada H, Akagi T, Tsuji T, and Oguma K. Gastric ulcers in SCID mice induced by Helicobacter pylori infection after transplanting lymphocytes from patients with gastric lymphoma. Gastroenterology. 117: 893-899, 1999.
46. Inoue K, Fujinaga Y, Honke K, Yokota K, Ikeda T, Ohyama T, Takeshi K, Watanabe T, Inoue K, and Oguma K. Characterization of hemagglutinin activity of Clostridium botulinum type C and D 16S toxins, and one subcomponent of HA (HA1). Microbiol. 145: 2533-2542, 1999.
47. Funamori Y, Fujinaga Y, Yokota K, Inoue K, Hirai Y, Oguma K, Kira S, and Taketa K. Molecular typing of enterohemorrhagic Escherichia coli O157: H7 isolated in Okayama prefecture using pulsed field gel electrophoresis and random amplification of polymorphic DNA. Acta Med. Okayama. 53: 193-200, 1999.
48. Watanabe T, Sagane Y, Kouguchi H, Sunagawa H, Inoue K, Fujinaga Y, Oguma K, and Ohyama T. Molecular composition of progenitor toxin produced by Clostridium botulinum type C strain 6813. J. Protein. Chem. 18: 753-760, 1999.
49. Takeshi K, Makino S, Ikeda T, Takeda N, Nakashiro A, Nakanishi K, Oguma K, Katoh Y, Sunagawa H, and Ohyama T. Direct and rapid detection by PCR of Erysipelothrix sp. DNAs prepared from bacterial strains and animal tissues. J. Clin. Microbiol. 37: 4093-4098, 1999.
50. Hirai Y, Hayashi S, Shimomura H, Oguma K, and Yokota K. Association of Helicobacter pylori with gastroduodenal diseases. Jpn. J. Infect. Dis. 52: 183-197, 1999.
51. Isogai E, Isogai H, Amano K, Yokota S, Hayashi S, Hirose K, Oguma K, Hirai Y, Asaka M, and Sugiyama T. Effect of Helicobacter pylori lipopolysaccharides on human polymorphonuclear neutrophils and endotherial cells. Biosci. Microflora. 18: 119-124, 1999.
52. Sagane Y, Watanabe T, Kouguchi H, Sunagawa H, Inoue K, Fujinaga Y, Oguma K, and Ohyama T. Dichain structure of botulinum neurotoxin: identification of cleavage sites in type C, D, and F neurotoxin molecules. J. Protein Chem. 18: 885-892, 1999.
2. Fujii N, Kimura K, Yashiki T, Tsuzuki K, Moriishi K, Syuto B, Yokosawa N, and Oguma K. Cloning and whole nucleotide sequence of the gene for light chain component of botulinum type E toxin from Clostridium butyricum strain BL6340 and Clostridium botulinum type E strain Mashike. Microbiol. Immunol. 36: 213-220, 1992.
3. Fujii N, Kwon K, Yashiki T, Isogai E, Isogai H, Kimura K, and Oguma K. Oligo-2', 5'-adenylate synthetase activity in cells persistently infected with human T-cell leukemia virus (HTLV-1). Microbiol. Immunol. 36: 425-429, 1992.
4. Yokota K, Hayashi S, Fujii N, Yoshikawa K, Kotake S, Isogai E, Ohno S, and Oguma K. Antibody response to oral Streptococci in Behcet's disease. Microbiol. Immunol. 36: 815-822, 1992.
5. Fujii N, Kimura K, Yokosawa N, Tsuzuki K, and Oguma K. A zinc-protease specific domain in botulinum and tetanus neurotoxins. Toxicon. 30: 1486-1488, 1992.
6. Yokosawa N, Fujii N, Tsuzuki K, Kimura K, Syuto B, Moriishi K, and Oguma K. Inhibition of norepinephrine secretion from digitonin permeabilized PC12 cells by botulinum type D toxin. Toxicon. 30: 1555-1562, 1992.
7. Fujii N, Kimura K, Yokosawa N, Yashiki T, Tsuzuki K, and Oguma K. The complete nucleotide sequence of the gene encoding the nontoxic component of Clostridium botulinum type E progenitor toxin. J. Gen. Microbiol. 139: 79-86, 1993.
8. Hayashi S, Yokota K, Takizawa Y, Tomizawa I, Nejime T, and Oguma K. Development and evaluation of capture enzyme-linked immunosorbent assays for detection of immunoglobulin G and M antibodies to group A streptococcal antigens. Microbiol. Immunol. 37: 271-279, 1993.
9. Fujii N, Kimura K, Yokosawa N, Oguma K, Yashiki T, Takeshi K, Ohyama T, Isogai E, and Isogai H. Similarity in nucleotide sequence of the gene encoding nontoxic component of botulinum toxin produced by toxigenic Clostridium butyricum strain BL6340 and Clostridium botulinum type E strain Mashike. Microbiol. Immunol. 37: 395-398, 1993.
10. Ishii N, Isogai E, Yamakawa Y, Nakajima H, Ohno S, Isogai H, Hayashi S, Yokota K, and Oguma K. Demonstration of antigen-specific immune response against Streptococcus sanguis. J. Dermatol. Sci. 5: 182-189, 1993.
11. Moriishi K, Shuto B, Saito M, Oguma K, Fujii N, Abe N, and Naiki M. Two different types of ADP-ribosyltransferase C3 from Clostridium botulinum type D lysogenized organisms. Infect. Immun. 61: 5309-5314, 1993.
12. Yokosawa N, Suga K, Kimura K, Tsuzuki, K, Fujii N, Oguma K, and Yokosawa H. Exogenous zinc ion is required for inhibitory activity of botulinum neurotoxin C1 against norepinephrine release and its endopeptidase activity toward substance P. Biochem. Mol. Bio. Int. 32: 455-463, 1994.
13. Yokota K, Hirai Y, Haque M, Hayashi S, Isogai H, Sugiyama T, Nagamachi E, Tsukada Y, Fujii N, and Oguma K. Heat shock protein produced by Helicobacter pylori. Microbiol. Immunol. 38: 403-405, 1994.
14. Isogai H, Isogai E, Kimura K, Fujii N, Yokota K, and Oguma K. Helicobacter pylori induces inflammation in mouse urinary bladder and pelvis. Microbiol. Immunol. 38: 331-336, 1994.
15. Fujinaga Y, Inoue K, Shimazaki S, Tomochika K, Tsuzuki K, Fujii N, Watanabe T, Ohyama T, Inoue K, and Oguma K. Molecular construction of Clostridium botulinum type C progenitor toxin and its gene organization. Biochem. Biophys. Res. Commun. 205: 1291-1298, 1994.
16. Ohyama T, Watanabe T, Fujinaga Y, Inoue K, Sunagawa H, Fujii N, Inoue K, and Oguma K. Characterization of Nontoxic-nonhemagglutinin component of the two types of progenitor toxin (M and L) produced by Clostridium botulinum Type D CB-16. Microbiol. Immunol. 39: 457-465, 1995.
17. Yokota K, Hayashi S, Araki Y, Isogai E, Kotake S, Yoshikawa K, Fujii N, Hirai Y, and Oguma K. Characterization of Streptococcus sanguis isolated from patients with Behchet’s disease. Microbiol. Immunol. 39: 729-732, 1995.
18. Haque M, Hirai Y, Yokota K, and Oguma K. Lipid profiles of Helicobacter pylori and Helicobacter mustelae grown in serum-supplemented and serum-free media. Acta Med. Okayama. 49: 205-211, 1995.
19. Fujinaga Y, Takeshi K, Inoue K, Fujita R, Ohyama T, Moriishi K, and Oguma K. Type A and B neurotoxin genes in a Clostridium botulinum type AB strain. Biochem. Biophys. Res. Commun. 213: 737-745, 1995.
20. Hirai Y, Haque M, Yoshida T, Yokota K, Yasuda T, and Oguma K. Unique cholesteryl glucosides in Helicobacter pylori: composition and structural analysis. J. Bacteriol. 177: 5327-5333, 1995.
21. Haque M, Hirai Y, Yokota K, and Oguma K. Steryl glycosides: a characteristic feature of the Helicobacter spp.? J. Bacteriol. 177: 5334-5337, 1995.
22. Fujita R, Fujinaga Y, Inoue K, Nakajima H, Kumon H, and Oguma K. Molecular characterization of two forms of nontoxic-nonhemagglutinin components of Clostridium botulinum type A progenitor toxins. FEBS lett. 376: 41-44, 1995.
23. Takeshi K, Fujinaga Y, Inoue K, Nakajina H, Oguma K, Ueno T, Sunagawa H, and Ohyama T. Simple method for detection of Clostridium botulinum type A to F neurotoxin genes by polymerase chain reaction. Microbiol. Immunol. 40: 5-11, 1996.
24. Moriishi K, Koura M, Fujii N, Fujinaga Y, Inoue K, Syuto B, and Oguma K. Molecular cloning of the gene encoding the mosaic neurotoxin, composed of parts of botulinum neurotoxin types C1 and D, and PCR detection of this gene from Clostridium botulinum type C organisms. Appl. Environ. Microbiol. 62: 662-667, 1996.
25. Haque M, Hirai Y, Yokota K, Mori N, Israt J. Ito H, Hotta H, Yano I, Kanemasa Y, and Oguma K. Lipid profile of Helicobacter spp.: presence of cholesteryl glucoside as a characteristic feature. J. Bacteriol. 178: 2065-2070, 1996.
26. Inoue K, Fujinaga Y, Watanabe T, Ohyama T, Takeshi K, Moriishi K, Nakajima H, Inoue K, and Oguma K. Molecular composition of Clostridium botulinum type A progenitor toxins. Infect. Immun. 64: 1589-1594, 1996.
27. Moriishi K, Koura M, Abe N, Fujii N, Fujinaga Y, Inoue K, and Oguma K. Mosaic structures of neurotoxins produced from Clostridium botulinum type C and D organisms. Biochim. Biophis. Acta. 1307: 123-126, 1996.
28. Hayashi S, Sugiyama T, Hisano K, Awakawa T, Kurokawa I, Yachi A, Isogai H, Isogai E, Yokota K, Hirai Y, Oguma K, and Fujii N. Quantitative detection of secretory immunogloblin A to Helicobacter pylori in gastric juice: antibody capture enzyme-linked immunosorbent assay. J. Clin. Lab. Analysis. 10: 74-77, 1996.
29. Isogai H, Isogai E, Hayashi S, Kimura K, Kubota T, Fujii N, and Oguma K. Experimental Helicobacter pylori infection in association with other bacteria. Microbiol. Immunol. 41: 361-365, 1997.
30. Hayashi S, Sugiyama T, Yachi A, Yokota K, Hirai Y, Oguma K, and Fujii N. A rapid and simple mathod to quantify Helicobacter pylori adhesion to human gastric MKN-28 cells. J. Gastroen. Hepatol. 12: 373-375, 1997.
31. Fujinaga Y, Inoue K, Watanabe S, Yokota K, Hirai K, Nagamachi E, and Oguma K. The haemagglutinin of Clostridium botulinum type C progenitor toxin plays an essential role in binding of toxin to the epithelial cells of guinea pig small intestine, leading to the efficient absorption of the toxin. Microbiol. 143: 3841-3847, 1997.
32. Yokota K, and Oguma K. IgA protease produced by Streptococcus sanguis, and antibody production against IgA protease in the patients with Bechet`s disease. Microbiol. Immunol. 41: 925-931, 1997.
33. Hayashi S, Sugiyama T, Yachi A, Yokota K, Hirai Y, Oguma K, and Fujii N. Effect of ecabet sodium on Helicobacter pylori adhesion to gastric epithelial cells. J. Gastroen. 32: 593-597, 1997.
34. Takeshi K, Ikeda T, Kubo A, Fujinaga Y, Makino S, Oguma K, Isogai E, Yoshida S, Sunagawa H, Ohyama T, and Kimura H. Direct datection by PCR of Escherichia coli O157 and enteropathogens in patients with bloody diarrhea. Microbiol. Immunol. 41: 819-822, 1997.
35. Kobayashi K, Yokota K, Yoshino T, Kawahara Y, Day A, Hirai Y, Oguma K, and Akagi T. Detection of Helicobacter pylori associated antigen and heat shock protein 60 on follicular dendritic cells in the germinal centers of low grade B cell lymphoma of gastric mucosa associated lymphoid tissue (MALT). J. Clin. Pathol. 51: 396-398, 1998.
36. Dey A, Yokota K, Kobayashi K, Oguma K, Hirai Y, and Akagi T. Antibody and cytokine responses in Helicobacter pylori-infected various mouse strains. Acta Med. Okayama. 5: 41-48, 1998.
37. Hayashi S, Sugiyama T, Amano k, Isogai H, Isogai E, Aihara M, Kikuchi M, Asaka M, Yokota K, Oguma K, Fujii N, and Hirai Y. Effect of rebamipide, a novel antiulcer agent, on Helicobacter pylori adhesion to gastric epithelial cells. Antimicrob. Agents. Chemother. 42: 1895-1899, 1998.
38. Nakajima H, Inoue K, Ikeda T, Fujinaga Y, Sunagawa H, Takeshi K, Ohyama T, Watanabe T, Inoue K, and Oguma K. Molecular composition of the 16S toxin produced by a Clostridium botulinum type D strain, 1873. Microbiol. Immunol. 42: 599-605, 1998.
39. Marvaud, J. C, Gibert M, Inoue K, Fujinaga Y, Oguma K, and Popoff M. R. botR/A is a positive regulator of botulinum neurotoxin and associated non-toxin protein genes in Clostridium botulinum A. Mol. Microbiol. 29: 1009-1018, 1998.
40. Yokota K, Fujinaga Y, Inoue K, Seo G, Takeshi K, Nagamachi E, and Oguma K. Classification of Clostridium butyricum based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis and pulsed-field gel electrophoresis. Anaerobe. 4: 177-181, 1998.
41. Hayashi S, Sugiyama T, Yokota K, Isogai H, Isogai E, Oguma K, Asaka M, Fujii N, and Hirai Y. Analysis of immunoglobulin a antibodies to Helicobacter pylori in serum and gastric juice in relation to mucosal inflammation. Clin. Diagn. Lab. Immunol. 5: 617-621, 1998.
42. Sasaki M, Hattori Y, Tomita F, Moriishi K, Kanno M, Kohya T, Oguma K, and Kitabatake A. Tyrosine phosphorylation as a convergent pathway of heterotrimeric G protein-and rho protein-mediated Ca++ sensitization of smooth muscle rabbit mesenteric artery. Br. J. Pharmacol. 125: 1651-1660, 1998.
43. Hayashi S, Sugiyama T, Asaka M, Yokota K, Oguma K, and Hirai Y. Modification of Helicobacter pylori adhesion to human gastric epithelial cells by antiadhesion agents. Digest. Dis. Sci. 43: 56-60, 1998.
44. Kawahara Y, Yokota K, Mizuno M, Yunoki M, Uesu T, Okada H, Kobayashi K, Hirai Y, Oguma K, and Tsuji T. Antibodies to human gastric epithelial cells and heat shock protein60 in Helicobacter pylori positive mucosa associated lymphoid tissue lymphoma. Gut.
45: 20-23, 1999. 45. Yokota K, Kobayashi K, Kawahara Y, Hayashi S, Hirai Y, Mizuno M, Okada H, Akagi T, Tsuji T, and Oguma K. Gastric ulcers in SCID mice induced by Helicobacter pylori infection after transplanting lymphocytes from patients with gastric lymphoma. Gastroenterology. 117: 893-899, 1999.
46. Inoue K, Fujinaga Y, Honke K, Yokota K, Ikeda T, Ohyama T, Takeshi K, Watanabe T, Inoue K, and Oguma K. Characterization of hemagglutinin activity of Clostridium botulinum type C and D 16S toxins, and one subcomponent of HA (HA1). Microbiol. 145: 2533-2542, 1999.
47. Funamori Y, Fujinaga Y, Yokota K, Inoue K, Hirai Y, Oguma K, Kira S, and Taketa K. Molecular typing of enterohemorrhagic Escherichia coli O157: H7 isolated in Okayama prefecture using pulsed field gel electrophoresis and random amplification of polymorphic DNA. Acta Med. Okayama. 53: 193-200, 1999.
48. Watanabe T, Sagane Y, Kouguchi H, Sunagawa H, Inoue K, Fujinaga Y, Oguma K, and Ohyama T. Molecular composition of progenitor toxin produced by Clostridium botulinum type C strain 6813. J. Protein. Chem. 18: 753-760, 1999.
49. Takeshi K, Makino S, Ikeda T, Takeda N, Nakashiro A, Nakanishi K, Oguma K, Katoh Y, Sunagawa H, and Ohyama T. Direct and rapid detection by PCR of Erysipelothrix sp. DNAs prepared from bacterial strains and animal tissues. J. Clin. Microbiol. 37: 4093-4098, 1999.
50. Hirai Y, Hayashi S, Shimomura H, Oguma K, and Yokota K. Association of Helicobacter pylori with gastroduodenal diseases. Jpn. J. Infect. Dis. 52: 183-197, 1999.
51. Isogai E, Isogai H, Amano K, Yokota S, Hayashi S, Hirose K, Oguma K, Hirai Y, Asaka M, and Sugiyama T. Effect of Helicobacter pylori lipopolysaccharides on human polymorphonuclear neutrophils and endotherial cells. Biosci. Microflora. 18: 119-124, 1999.
52. Sagane Y, Watanabe T, Kouguchi H, Sunagawa H, Inoue K, Fujinaga Y, Oguma K, and Ohyama T. Dichain structure of botulinum neurotoxin: identification of cleavage sites in type C, D, and F neurotoxin molecules. J. Protein Chem. 18: 885-892, 1999.
1992〜1999年 原著論文（計52報）