研究業績

2024年

Mikami A, Hyodo A, Horie K, Yasumatsu K, Ninomiya Y, Mitoh Y, Iida S, Yoshida R.
The role of GABA in modulation of taste signaling within the taste bud.
Pflugers Archiv, doi:10.1007/s00424-024-03007-x PMID:39210062
Open Access

Yoshida R, Ninomiya Y.
Mechanisms and Functions of Sweet Reception in Oral and Extraoral Organs.
International Journal of Molecular Sciences, 25:7398 doi:10.3390/ijms25137398 PMID:39000505
Open Access

Hyodo A, Mikami A, Horie K, Mitoh Y, Ninomiya Y, Iida S, Yoshida R.
Salivary buffering capacity is correlated with umami but not sour taste sensitivity in healthy adult Japanese subjects
Archieves of Oral Biology, 165:106013. doi:10.1016/j.archoralbio.2024.106013. PMID:38833772
岡山大学学術成果レポジトリ

Nishitani T, Mitoh Y, Yajima T, Tachiya D, Hoshika T, Fukunaga T, Nishitani Y, Yoshida R, Mizoguchi I, Ichikawa H, Sato T.
Distribution of alpha-synuclein in rat salivary glands
Anatomical Reports, 307(8):2933-2946. doi:10.1002/ar.25395. PMID: 38284507
Open Access


2023年

Yoshida R.
Sensory Systems for Sugar-Induced Cephalic Phase Insulin Release
Current Oral Health Reports, 10:117-123. doi:10.1007/s40496-023-00347-y.
Open Access

Takamori M, Mitoh Y, Horie K, Egusa M, Miyawaki T, Yoshida R.
Sugar signals from oral glucose transporters elicit cephalic-phase insulin release in mice
Journal of Physiological Science, 73:16. doi:10.1186/s12576-023-00875-3. PMID:37525102
Open Access

Iwata S, Yoshida R, Takai S, Sanematsu K, Shigemura N, Ninomiya Y.
Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via T1R-Independent Sweet Taste Pathway.
Nutrients, 15:2941. doi:10.3390/nu15132941. PMID:37447268
Open Access

Yamase Y, Huang H, Mitoh Y, Egusa M, Miyawaki T, Yoshida R.
Taste Responses and Ingestive Behaviors to Ingredients of Fermented Milk in Mice.
Foods, 12:1150 doi:10.3390/foods12061150. PMID:36981077
Open Access

Kobashi M, Shimatani Y, Fujita M.
Oxytocin increased intragastric pressure in the forestomach of rats via the dorsal vagal complex.
Physiology and Behavior, 261:114087. doi: 10.1016/j.physbeh.2023.114087. PMID:36646162
岡山大学学術成果レポジトリ

Kawabata Y, Takai S, Sanematsu K, Yoshida R, Kawabata F, Shigemura N.
The Antiarrhythmic Drug Flecainide Enhances Aversion to HCl in Mice.
eNeuro, 10:ENEURO.0048-23.2023 doi: 10.1523/ENEURO.0048-23.2023. PMID:37696662
Open Access

Yamada R, Tanaka Y, Sugimoto H*, Kodama N, Yoshida R, Minagi S.
Effect of continuous sweet gustatory stimulation on salivary flow rate over time.
Archives of Oral Biology 146:105590. doi:10.1016/j.archoralbio.2022.105590. PMID:36463789

Yoshida R, Ninomiya Y.
Chapter 2: Umami and MSG.
Umami: Taste for Health, 2023, (Elsevier)
Open Access


2022年

吉田竜介
味覚
歯科衛生士シリーズ:口腔解剖学・口腔組織発生学・口腔生理学 200-206 医 歯薬出版

吉田竜介
研究室紹介(岡山大学大学院医歯薬学総合研究科口腔生理学分野
日本味と匂学会誌 29: 113-116


2021年

Yoshida R, Yasumatsu K, Ninomiya Y.
The sweet taste receptor, glucose transporters, and the ATP-sensitive K+ (KATP) channel: Sugar sensing for the regulation of energy homeostasis
Current Opinion in Physiology. 20:57-63 doi:10.1016/j.cophys.2021.01.009
岡山大学学術成果レポジトリ

Yoshida R, Margolskee RF, Ninomiya Y.
Phosphatidylinositol‐3 kinase mediates the sweet suppressive effect of leptin in mouse taste cells.
Journal of Neurochemistry. 158:233-245, doi:10.1111/jnc.15268. PMID:33319361
岡山大学学術成果レポジトリ


2020年

Sato T, Yajima T, Fujita M, Kobashi M, Ichikawa H, Yoshida R, Mitoh Y.
Orexin A and B in the rat superior salivatory nucleus.
Autonomic Neuroscience. 228:102712, doi: 10.1016/j.autneu.2020.102712. PMID:32721850
岡山大学学術成果レポジトリ

Yasumatsu K, Ohkuri T, Yoshida R, Iwata S, Margolskee RF, Ninomiya Y.
Sodium‐glucose cotransporter 1 as a sugar taste sensor in mouse tongue.
Acta Physiologica. 230:e13529, doi: 10.1111/apha.13529. PMID:32599649

Kobashi M, Shimatani Y, Fujita M, Mitoh Y, Yoshida R, Matsuo R.
The Effects of Mutual Interaction of Orexin-A and Glucagon-Like Peptide-1 on Reflex Swallowing Induced by SLN Afferents in Rats.
International Journal of Molecular Sciences. 21:E4422, doi: 10.3390/ijms21124422. PMID:32580304
岡山大学学術成果レポジトリ

Masamoto M, Mitoh Y, Kobashi M, Shigemura N, Yoshida R.
Effects of bitter receptor antagonists on behavioral lick responses of mice.
Neuroscience letters. 730:135041, doi: 10.1016/j.neulet.2020.135041. PMID:32413538
岡山大学学術成果レポジトリ

Yoshida R, Ninomiya Y.
Section 21: 3.10 - Sweet and Umami Taste
The Senses: A Comprehensive Reference, Reference Work, 2nd Edition, 2021 (Elsevier)


2019年

Takai S, Watanabe Y, Sanematsu K, Yoshida R, Margolskee RF, Jiang P, Atsuta I, Koyano K, Ninomiya Y, Shigemura N.
Effects of insulin signaling on mouse taste cell proliferation.
PLoS One. 14:e0225190, doi: 10.1371/journal.pone.0225190. PMID:31714935

Shigemura N, Takai S, Hirose F, Yoshida R, Sanematsu K, Ninomiya Y.
Expression of Renin-Angiotensin System Components in the Taste Organ of Mice.
Nutrients. 11: E2251, 2019, doi: 10.3390/nu11092251, PMID:31546789

Ohla K, Yoshida R, Roper SD, Di Lorenzo PM, Victor JD, Boughter Jr JD, Fletcher M, Katz DB, Chaudhari N.
Recognizing taste: coding patterns along the neural axis in mammals.
Chemical Senses. 44: 237-247, 2019, doi: 10.1093/chemse/bjz013, PMID:30788507

吉田竜介, 實松敬介, 高井信吾, 岩田周介, 重村憲徳.
ヒト味覚認知閾値に対する低濃度塩添加の影響.
日本味と匂学会誌第53回大会Proceeding集. S35-S38, 2019

美藤純弘, 佐藤匡, 矢島健大, 藤田雅子, 小橋基, 市川博之, 吉田竜介.
摂食亢進ペプチドのラット顎下腺・舌下腺支配の副交感神経節前ニューロンに対する影響.
日本味と匂学会誌第53回大会Proceeding集. S55-S58, 2019

吉田竜介.
末梢味覚器におけるうま味のコーディング.
日本味と匂学会誌. 26: 71-76, 2019

吉田竜介.
末梢における味覚情報伝達.
岡山歯学会雑誌. 38: 25-36, 2019


2018年

Yoshida R, Takai S, Sanematsu K, Margolskee RF, Shigemura N, Ninomiya Y.
Bitter Taste Responses of Gustducin-positive Taste Cells in Mouse Fungiform and Circumvallate Papillae.
Neuroscience. 369: 29-39, 2018, PMID:29113930
岡山大学学術成果レポジトリ

Matsuo R, Kobashi M, Fujita M.
Electrophysiological study on sensory nerve activity from the submandibular salivary gland in rats.
Brain Research. 1680: 137-142, 2018, PMID:29269052


2017年

Yoshida R, Shin M, Yasumatsu K, Takai S, Inoue M, Shigemura N, Takiguchi S, Nakamura S, Ninomiya Y.
The Role of Cholecystokinin in Peripheral Taste Signaling in Mice.
Frontiers in Physiology. 8: 886. 2017, PMID:29163209

Kobashi M, Mizutani S, Fujita M, Mitoh Y, Shimatani Y, Matsuo R.
Central glucagon like peptide-1 inhibits reflex swallowing elicited by the superior laryngeal nerve via caudal brainstem in the rat.
Brain Research. 1671: 26-32. 2017, PMID:28693820

Mitoh Y, Ueda H, Ichikawa H, Fujita M, Kobashi M, Matsuo R.
Effects of cevimeline on excitability of parasympathetic preganglionic neurons in the superior salivatory nucleus of rats.
Autonomic Neuroscience. 206: 1-7. 2017, PMID:28600120

岩田周介, 安松啓子, 井上真由子, 吉田竜介, 重村憲徳, 二ノ宮裕三.
アンジオテンシンIIのT1Rs非依存的甘味応答に及ぼす影響.
日本味と匂学会誌. 24: S31-S34, 2017


2016年

Jyotaki M, Sanematsu K, Shigemura N, Yoshida R, Ninomiya Y.
Leptin suppresses sweet taste responses of enteroendocrine STC-1 cells.
Neuroscience. 332: 76-87, 2016, PMID:27353597

Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya Y.
Intracellular acidification is required for full activation of the sweet taste receptor by miraculin.
Scientific Reports. 6: 22807, 2016, PMID:26960429

Yoshida R, Ninomiya Y.
Taste information derived from T1R-expressing taste cells in mice.
Biochemical Journal. 473: 525-536, 2016, PMID:26912569

Takai S, Yoshida R, Yasumatsu K, Shigemura N, Ninomiya Y.
The function of glucagon-like peptide-1 in the mouse peripheral taste system.
Journal of Oral Bioscience. 58: 10-15, 2016

吉田竜介, 二ノ宮裕三.
甘味受容体を起点とした口腔脳腸の味情報−内分泌連関と食調節.
食品加工技術. 36: 30-38, 2016

美藤純弘, 藤田雅子, 小橋基, 松尾龍二.
前脳による唾液分泌の調節.
日本歯科評論. 76: 145-150, 2016


2015年

Yoshida R, Noguchi K, Shigemura N, Jyotaki M, Takahashi I, Margolskee RF, Ninomiya Y.
Leptin Suppresses Mouse Taste Cell Responses to Sweet Compounds.
Diabetes. 64: 3751-3762, 2015, PMID:26116698

Niki M, Jyotaki M, Yoshida R, Yasumatsu K, Shigemura N, DiPatrizio NV, Piomelli D, Ninomiya Y.
Modulation of sweet taste sensitivities by endogenous leptin and endocannabinoids in mice.
Journal of Physiology. 593: 2527-2545, 2015, PMID:25728242

Takai S, Yasumatsu K, Inoue M, Iwata S, Yoshida R, Shigemura N, Yanagawa Y, Drucker DJ, Margolskee RF, Ninomiya Y.
Glucagon-like peptide-1 is specifically involved in sweet taste transmission.
FASEB Journal. 29: 2268-2280, 2015, PMID:25678625

Yasumatsu K, Manabe T, Yoshida R, Iwatsuki K, Uneyama H, Takahashi I, Ninomiya Y.
Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice.
Journal of Physiology. 593: 1021-1034, 2015, PMID:25529865

Matsuo R, Kobashi M, Mitoh Y, Fujita M.
Role of the lateral hypothalamus in submandibular salivary secretion during feeding in rats.
Brain Research. 1596: 99-107, 2015, PMID:25446459


2014年

Sanematsu K, Yoshida R, Shigemura N, Ninomiya Y.
Structure, function, and signaling of taste G-protein-coupled receptors.
Current Pharmaceutical Biotechnology. 15: 951-61, 2014, PMID:25248559

Iwata S, Yoshida R, Ninomiya Y.
Taste transductions in taste receptor cells: basic tastes and moreover.
Current Pharmaceutical Design. 20: 2684-92, 2014, PMID:23886388

Kobashi M, Mizutani S, Fujita M, Mitoh Y, Shimatani Y, Matsuo R.
Central orexin inhibits reflex swallowing elicited by the superior laryngeal nerve via caudal brainstem in the rat.
Physiology and Behavier. 130: 6-12, 2014, PMID:24637063

Maeda N, Kobashi M, Mitoh Y, Fujita M, Minagi S, Matsuo R.
Differential involvement of two cortical masticatory areas in submandibular salivary secretion in rats.
Brain Research. 1543: 200-208, 2014, PMID:24309141

高井信吾, 安松啓子, 吉田竜介, 重村憲徳, 二ノ宮裕三.
味神経に発現するGLP-1レセプターとその役割.
日本味と匂学会誌. 21: 253-256, 2014

岩田周介, 吉田竜介, 重村憲徳, 二ノ宮裕三.
アンギオテンシンIIによるエンドカンナビノイド受容体を介した甘味の増強.
日本味と匂学会誌. 21: 259-262, 2014


2013年

Shigemura N, Iwata S, Yasumatsu K, Ohkuri T, Horio N, Sanematsu K, Yoshida R, Margolskee RF, Ninomiya Y.
Angiotensin II Modulates Salty and Sweet Taste Sensitivities.
Journal of Neuroscience. 33: 6267-6277, 2013, PMID:23575826

Kusuhara Y, Yoshida R, Ohkuri T, Yasumatsu K, Voigt A, H?bner S, Maeda K, Boehm U, Meyerhof W, Ninomiya Y.
Taste responses in mice lacking taste receptor subunit T1R1.
Journal of Physiology. 591: 1967-1985, 2013, PMID:23339178

Yoshida R, Niki M, Jyotaki M, Sanematsu K, Shigemura N, Ninomiya Y.
Modulation of sweet responses of taste receptor cells.
Seminars in Cell & Developmental Biology. 24: 226-231, 2013, PMID:22947916

吉田竜介, 二ノ宮裕三.
味細胞における味の伝達機構.
JOHNS. 29: 13-15, 2013


2012年

Yasumatsu K, Ogiwara Y, Takai S, Yoshida R, Iwatsuki K, Torii K, Margolskee RF, Ninomiya Y.
Umami taste in mice uses multiple receptors and transduction pathways.
Journal of Physiology. 590: 1155-1170, 2012, PMID:22183726

Yoshida R.
Hormones and bioactive substances that affect peripheral taste sensitivity.
Journal of Oral Bioscience. 54: 67-72, 2012

吉田竜介, 二ノ宮裕三.
食欲調節物質による甘味感受性の調節.
日本薬理学会雑誌. 139: 131, 2012


2011年

Niki M, Takai S, Kusuhara Y, Ninomiya Y, Yoshida R.
Responses to apical and basolateral application of glutamate in mouse fungiform taste cells with action potentials.
Cellular and Molecular Neurobiology. 31: 1033-1040, 2011, PMID:21573975

Horio N, Yoshida R, Yasumatsu K, Yanagawa Y, Ishimaru Y, Matsunami H, Ninomiya Y.
Sour Taste Responses in Mice Lacking PKD Channels.
PLoS ONE. 6: e20007, 2011, PMID:21625513

Ueda H, Mitoh Y, Fujita M, Kobashi M, Yamashiro T, Sugimoto T, Ichikawa H, Matsuo R.
Muscarinic receptor immunoreactivity in the superior salivatory nucleus neurons innervating the salivary glands of the rat.
Neuroscience Letters. 499: 42-46, 2011, PMID:21624431

仁木麻由, 上瀧将史, 吉田竜介, 二ノ宮裕三.
レプチン受容体アンタゴニストによるマウスの甘味応答.
日本味と匂学会誌. 18: 255-259, 2011


2010年以前

Murata Y, Yasuo T, Yoshida R, Obata K, Yanagawa Y, Margolskee RF, Ninomiya Y.
Action potential-enhanced ATP release from taste cells through hemichannels.
Journal of Neurophysiology. 104: 896-901, 2010, PMID:20519578

Cartoni C, Yasumatsu K, Ohkuri T, Shigemura N, Yoshida R, Godinot N, le Coutre J, Ninomiya Y, Damak S.
Taste preference for fatty acids is mediated by GPR40 and GPR120.
Journal of Neuroscience. 30: 8376-8382, 2010, PMID:20573884

Yoshida R, Ohkuri T, Jyotaki M, Yasuo T, Horio N, Yasumatsu K, Sanematsu K, Shigemura N, Yamamoto T, Margolskee RF, Ninomiya Y.
Endocannabinoids selectively enhance sweet taste.
Proceedings of National Academy of Sciences of the United States of America. 107: 935-939, 2010, PMID:20080779

Yoshida R, Niki M, Murata Y, Shigemura N, Ninomiya Y.
Reception and transmission of taste information in Type II and Type III taste bud cells.
Journal of Oral Bioscience. 52: 358-364, 2010

Niki M, Yoshida R, Takai S, Ninomiya Y.
Gustatory Signaling in the Periphery: Detection, Transmission, and Modulation of Taste Information.
Biological & Pharmaceutical Bulletin. 33: 1772-1777, 2010, PMID:21048297

Niki M, Jyotaki M, Yoshida R, Ninomiya Y.
Reciprocal modulation of sweet taste by leptin and endocannabinoids.
Results and Problems in Cell Differentiation. 52: 101-114, 2010, PMID:20865375

Yoshida R, Ninomiya Y.
New Insights into the Signal Transmission from Taste Cells to Gustatory Nerve Fibers.
International Review of Cell and Molecular Biology. 279: 101-134, 2010, PMID:20797678

Horio N, Jyotaki M, Yoshida R, Sanematsu K, Shigemura N, Ninomiya Y.
New frontiers in gut nutrient sensor research: nutrient sensors in the gastrointestinal tract: modulation of sweet taste sensitivity by leptin.
Journal of Pharmacological Sciences. 112: 8-12, 2010, PMID:20093782

Kobashi M, Xuan SY, Fujita M, Mitoh Y, Matsuo R.
Central ghrelin inhibits reflex swallowing elicited by activation of the superior laryngeal nerve in the rat.
Regulatory Peptides. 160: 19-25, 2010, PMID:20045031

安尾敏明, 吉田竜介, 柳川右千夫, Margolskee RF, 二ノ宮裕三.
マウス味細胞の味応答時におけるGABAの作用.
日本味と匂学会誌. 17: 227-230, 2010

仁木麻由, 大栗弾宏, 上瀧将史, 吉田竜介, 二ノ宮裕三.
エンドカンナビノイド受容体アンタゴニストによるdb/dbマウスにおける甘味応答抑制.
日本味と匂学会誌. 17: 231-234, 2010

吉田竜介, 大栗弾宏, 重村憲徳, 二ノ宮裕三.
内因性カンナビノイドの甘味増強作用.
実験医学. 28: 1405-1408, 2010

吉田竜介, 仁木麻由, 二ノ宮裕三.
末梢における味覚受容・情報伝達とその調節.
Clinical Neuroscience. 28: 1227-1231, 2010

Yoshida R, Miyauchi A, Yasuo T, Jyotaki M, Murata Y, Yasumatsu K, Shigemura N, Yanagawa Y, Obata K, Ueno H, Margolskee RF, Ninomiya Y.
Discrimination of taste qualities among mouse fungiform taste bud cells.
Journal of Physiology. 587: 4425-4439, 2009, PMID:19622604

Yoshida R, Horio N, Murata Y, Yausmatsu K, Shigemura N, Ninomiya Y.
NaCl responsive taste cells in the mouse fungiform taste buds.
Neuroscience. 159: 795-803, 2009, PMID:19167465

Shigemura N, Shirosaki S, Sanematsu K, Yoshida R, Ninomiya Y.
Genetic and molecular basis of individual differences in human umami taste perception.
PLoS ONE. 4: e6717, 2009, PMID:19696921

Yoshida R, Yasumatsu K, Shirosaki S, Jyotaki M, Horio N, Murata Y, Shigemura N, Nakashima K, Ninomiya Y.
Multiple receptor systems for umami taste in mice.
Annals of the New York Academy of Sciences. 1170: 51-54, 2009, PMID:19686107

Sanematsu K, Horio N, Murata Y, Yoshida R, Ohkuri T, Shigemura N, Ninomiya Y.
Modulation and transmission of sweet taste information for energy homeostasis.
Annals of the New York Academy of Sciences. 1170: 102-106, 2009, PMID:19686118

Yasumatsu K, Horio N, Murata Y, Ohkuri T, Yoshida R, Ninomiya Y.
Multiple receptors and transduction underlie umami taste reception in mice.
American Journal of Clinical Nutrition. 90: 747S-752S, 2009, PMID:19571210

Shigemura N, Shirosaki S, Ohkuri T, Sanematsu K, Islam AS, Ogiwara Y, Kawai M, Yoshida R, Ninomiya Y.
Postnatal development of inhibitory synaptic transmission to superior salivatory neurons in rats.
American Journal of Clinical Nutrition. 90: 764S-769S, 2009, PMID:19625681

Kobashi M, Yanagihara M, Fujita M, Mitoh Y, Matsuo R.
Fourth ventricular administration of ghrelin induces relaxation of the proximal stomach in the rat.
American Journal of Physiology, Regulatory, Integrative and Comparative Physiology. 296: R217-R223, 2009, PMID:19036830

Mitoh Y, Funahashi M, Fujita M, Kobashi M, Matsuo R.
Variation in umami perception and in candidate genes for the umami receptor in mice and humans.
Journal of Medical Investigation. 56: Suppl270-272, 2009, PMID:20224199

Ueda H, Mitoh Y, Ichikawa H, Kobashi M, Yamashiro T, Matsuo R.
Cevimeline enhances the excitability of rat superior salivatory neurons.
Journal of Medical Investigation. 56: Suppl267-269, 2009, PMID:20224198

Matsushima A, Ichikawa H, Fujita M, Mitoh Y, Kobashi M, Yamashiro T, Matsuo R.
Immunohistochemical study on the distribution and origin of GABAergic nerve terminals in the superior salivatory nucleus.
Journal of Medical Investigation. 56: Suppl264-266, 2009, PMID:20224197

安尾敏明, 吉田竜介, 堀尾奈央, 重村憲徳, 二ノ宮裕三.
マウス味細胞におけるGABAの機能解析.
日本味と匂学会誌. 16: 323-326, 2009

吉田竜介, 二ノ宮裕三.
味覚情報のコーディングにおける味細胞の役割.
日本味と匂学会誌. 16: 117-124, 2009

Taravera K, Yasumatsu K, Yoshida R, Margolskee RF, Voets T, Ninomiya Y, Nilius B.
The taste transduction channel TRPM5 is a locus for bitter-sweet taste interactions.
FASEB Journal. 22: 1343-1355, 2008, PMID:18070821

Shigemura N, Ohkuri T, Sadamitsu C, Yasumatsu K, Yoshida R, Beauchamp GK, Bachmanov AA, Ninomiya Y.
Amiloride-sensitive NaCl taste responses are associated with genetic variation of ENaC alpha-subunit in mice.
American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 294: R66-75, 2008, PMID:17977920

Mitoh Y, Funahashi M, Fujii A, Fujita M, Kobashi M, Matsuo R.
Development of inhibitory synaptic transmission to the superior salivatory nucleus in rats.
Brain Research. 1191: 47-54, 2008, PMID:18155184

吉田竜介, 村田芳博, 安尾敏明, 上瀧将史, 柳川右千夫, 小幡邦彦, 植野洋志, Margolskee RF, 二ノ宮裕三.
味細胞の細胞型と応答特性.
日本味と匂学会誌. 15: 285-288, 2008

城崎慎也, 川東由利子, 中島清人, 重村憲徳, 安松啓子, 吉田竜介, Margolskee RF, 二ノ宮裕三.
mGluRアンタゴニスト混合うま味溶液に対するT1r3-KOおよびC57BL/6マウスの行動学的解析.
日本味と匂学会誌. 15: 293-296, 2008

村田芳博, 吉田竜介, 安尾敏明, 柳川右千夫, 小幡邦彦, 植野洋志, Margolskee RF, 二ノ宮裕三.
マウスII型味細胞の発火頻度依存性ATP放出.
日本味と匂学会誌. 15: 381-384, 2008

Hisatsune C, Yasumatsu K, Takahashi-Iwanaga H, Ogawa N, Kuroda Y, Yoshida R, Ninomiya Y, Mikoshiba K.
Abnormal taste perception in mice lacking the type 3 inositol 1,4,5-triphosphate receptor.
Journal of Biological Chemistry. 282: 37225-37231, 2007, PMID:17925404

Kodama N, Funahashi M, Mitoh Y, Minagi S, Matsuo R.
Purinergic modulation of area postrema neuronal excitability in rat brain slices.
Brain Research. 1165: 50-59, 2007, PMID:17658494

城崎慎也, 川東由利子, 中島清人, 重村憲徳, 安松啓子, 吉田竜介, Margolskee RF, 二ノ宮裕三.
T1R3-KOマウスにおけるうま味物質に対する条件付け味覚嫌悪学習.
日本味と匂学会誌. 14: 379-382, 2007

安松啓子, 大栗弾宏, 吉田竜介, Damak S, Margolskee RF, 二ノ宮裕三.
塩味、酸味、苦味物質混合によるマウス鼓索神経甘味応答の修飾.
日本味と匂学会誌. 14: 387-390, 2007

村田芳博, 安尾敏明, 吉田竜介, 二ノ宮裕三.
マウス茸状乳頭味細胞のATP放出.
日本味と匂学会誌. 14: 391-394, 2007

吉田竜介, 安尾敏明, 村田芳博, 上瀧将史, 二ノ宮裕三.
単一細胞応答の観点からみたマウス茸状乳頭味蕾の応答性.
日本味と匂学会誌. 14: 395-398, 2007

吉田竜介, 安松啓子, 二ノ宮裕三.
活動電位を発生する味細胞は味覚情報伝達経路の起始点となりうる.
日本味と匂学会誌. 14: 163-170, 2007

重村憲徳, 安松啓子, 吉田竜介, 二ノ宮裕三.
甘味感受性に影響する温度依存的なTrpm5の働き.
低温生物工学会誌. 53: 53-55, 2007

Yoshida R, Shigemura N, Sanematsu K, Yasumatsu K, Ishizuka S, Ninomiya Y.
Taste responsiveness of fungiform taste cells with action potentials.
Journal of Neurophysiology. 96: 3088-3095, 2006, PMID:16971686

Ohkuri T, Yasumatsu K, Shigemura N, Yoshida R, Ninomiya Y.
Amiloride inhibition on NaCl responses of the Chorda Tympani nerve in two 129 strains of mice, 129P3/J and 129X1/SvJ.
Chemical Senses. 31: 565-572, 2006

Damak S, Rong M, Yasumatsu K, Kokrashvili Z, Perez CA, Shigemura N, Yoshida R, Mosinger B Jr, Glendinning JI, Ninomiya Y, Margolskee RF.
Trpm5 null mice respond to bitter, sweet and umami compounds.
Chemical Senses. 31: 253-264, 2006, PMID:16436689

Yoshida R, Yasumatsu K, Shigemura N, Ninomiya Y.
Coding channels for taste perception: information transmission from taste cells to gustatory nerve fibers.
Archives of Histology and Cytology. 69: 233-242, 2006, PMID:17287578

Funahashi M, Mitoh Y, Akaike T, Matsuo R.
Variety of morphological and electrophysiological properties of area postrema neurons in adult rat brain slices.
Neuroscience Research. 54: 43-48, 2006, PMID:16293330

Kobashi M, Shimatani Y, Shirota K, Xuan SY, Mitoh Y, Matsuo R.
Variety of morphological and electrophysiological properties of area postrema neurons in adult rat brain slices.
American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 290: R290-R297, 2006, PMID:16195495

大倉哲也, 安松啓子, 伊藤由美子, 吉田竜介, 河合崇行, 日下部裕子, 進藤洋一郎, 日野明寛, 二ノ宮裕三.
塩味代替物・増強物質の利用による塩味受容機構の解析.
日本味と匂学会誌. 13: 279-280, 2006

安松啓子, 吉田竜介, 重村憲徳, Damak S, Margolskee RF, 二ノ宮裕三.
T1r3-KO、TRPM5-KOマウス鼓索神経におけるうま味応答神経線維の解析.
日本味と匂学会誌. 13: 335-338, 2006

大栗弾宏, 安松啓子, 吉田竜介, 重村憲徳, 二ノ宮裕三.
C57BL/6NとBALB/cマウスの鼓索神経甘味応答の刺激温度による変化.
日本味と匂学会誌. 13: 339-342, 2006

實松啓介, 安松啓子, 吉田竜介, 重村憲徳, 二ノ宮裕三.
Tas1r3遺伝子型とグルマリン感受性の関連.
日本味と匂学会誌. 13: 343-346, 2006

城崎慎也, 重村憲徳, 吉田竜介, 安松啓子, Margolskee RF, 二ノ宮裕三.
T1r3-KOマウスの甘味物質に対する行動応答解析.
日本味と匂学会誌. 13: 347-350, 2006

吉田竜介, 大栗弾宏, 安松啓子, 重村憲徳, 二ノ宮裕三.
マウス茸状乳頭味細胞のNaCl応答:アミロライド感受性細胞と非感受性細胞.
日本味と匂学会誌. 13: 351-354, 2006

重村憲徳, 大栗弾宏, 貞光千春, 安松啓子, 吉田竜介, Bachmanov AA, Beauchamp GK, 二ノ宮裕三.
ENaC遺伝子多型性とアミロライド感受性との相関.
日本味と匂学会誌. 13: 351-354, 2006

重村憲徳, 太田理絵, 杉田大悟, 山田礼子, 吉田竜介, 安松啓子, 二ノ宮裕三.
口は食べ物認識の見張り役.
歯界展望. 107: 597-602, 2006

Shigemura N, Islam AA, Sadamitsu C, Yoshida R, Yasumatsu K, Ninomiya Y.
Expression of amiloride-sensitive epithelial sodium channels in mouse taste cells after chorda tympani nerve crush.
Chemical Senses. 30: 531-538, 2005, PMID:16030075

Sanematsu K, Yasumatsu K, Yoshida R, Shigemura N, Ninomiya Y.
Mouse strain differences in Gurmarin-sensitivity of sweet taste responses are not associated with polymorphisms of the sweet receptor gene, Tas1r3.
Chemical Senses. 30: 491-496, 2005, PMID:15932937

Yoshida R, Sanematsu K, Shigemura N, Yasumatsu K, Ninomiya Y.
Taste receptor cells responding with action potentials to taste stimuli and their molecular expression of taste related genes.
Chemical Senses. 30: i19-20, 2005, PMID:15738107

Yasumatsu K, Shigemura N, Yoshida R, Ninomiya Y.
Recovery of salt responses and PGP 9.5 immunoreactive taste bud cells during regeneration of the mouse chorda tympani nerve.
Chemical Senses. 30: i62-i63, 2005, PMID:157381975

Shigemura N, Yasumatsu K, Yoshida R, Sako N, Katsukawa H, Nakashima K, Imoto T, Ninomiya Y.
The role of the dpa locus in mice.
Chemical Senses. 30: i84-i85, 2005, PMID:15738208

Kohjitani A, Funahashi M, Miyawaki T, Hanazaki M, Matsuo R, Shimada M.
Peripheral N-methyl-D-aspartate receptors modulate nonadrenergic noncholinergic lower esophageal sphincter relaxation in rabbits.
Anesthesia and Analgesia. 10: 1681-1688, 2005, PMID:16301241

Kobashi M, Ichikawa H, Kobashi M, Funahashi M, Mitoh Y, Matsuo R.
The origin of sensory nerve fibers that innervate the submandibular salivary gland in the rat.
Braain Research. 1060: 184-187, 2005, PMID:16188241

Kobashi M, Koga T, Mizutani M, Matsuo R.
Neural mechanism and possible role of inhibition of gastric motility induced by superior laryngeal afferents.
Chemical Senses. 30: i72-i73, 2005, PMID:15738202

吉田竜介, 重村憲徳, 安松啓子, 二ノ宮裕三.
脳へ味を伝える:味のニューラルコーディングチャネルの形成.
日本味と匂学会誌. 12: 259-262, 2005

城崎慎也, 重村憲徳, 吉田竜介, 安松啓子, Margolskee RF, 二ノ宮裕三.
TRPM5-KOマウスのキニーネに対する行動応答の解析.
日本味と匂学会誌. 12: 373-376, 2005

吉田竜介, 重村憲徳, 安松啓子, 二ノ宮裕三.
レプチンによる甘味感受性の修飾.
生体の科学. 56: 109-113, 2005

Funahashi M, Mitoh Y, Matsuo R.
Nicotinic modulation of area postrema neuronal excitability in rat brain slices.
Brain Research. 1017: 227-233, 2004, PMID:15261119

Funahashi M, Mitoh Y, Matsuo R.
The sensitivity of hyperpolarization-activated cation current (Ih) to propofol in rat area postrema neurons.
Brain Research. 1015: 198-201, 2004, PMID:15223387

Mitoh Y, Funahashi M, Kobashi M, Matsuo R.
Excitatory and inhibitory postsynaptic currents of the superior salivatory nucleus innervating the salivary glands and tongue in the rat.
Brain Research. 999: 62-72, 2004, PMID:14746922

Yoshida R, Nagahama T.
Search for cerebral G cluster neurons responding to taste stimulation with seaweed in Aplysia kurodai by the use of calcium imaging.
Journal of Neurobiology. 55: 299-314, 2003, PMID:12717700

Funahashi M, Mitoh Y, Kohjitani A, Matsuo R.
Role of the hyperpolarization-activated cation current (Ih) in pacemaker activity in area postrema neurons of rat brain slices.
Journal of Physiology. 552: 135-148, 2003, PMID:12897173

Higuchi H, Funahashi M, Miyawaki T, Mitoh Y, Kohjitani A, Shimada M, Matsuo R.
Suppression of the hyperpolarization-activated inward current contributes to the inhibitory actions of propofol on rat CA1 and CA3 pyramidal neurons.
Neuroscience Research. 45: 459-472, 2003, PMID:12657459

Kohjitani A, Miyawaki T, Funahashi M, Mitoh Y, Matsuo R, Shimada M.
Mexiletine inhibits nonadrenergic noncholinergic lower oesophageal sphincter relaxation in rabbits.
Europian Journal of Pharmacology. 465: 145-151, 2003, PMID:12650844

Kohjitani A, Miyawaki T, Funahashi M, Higuchi H, Matsuo R, Shimada M.
Ketamine and midazolam differentially inhibit nonadrenergic noncholinergic lower esophageal sphincter relaxation in rabbits: role of superoxide anion and nitric oxide synthase.
Anesthesiology. 98: 449-458, 2003, PMID:12552205

Koga T, Kobashi M, Mizutani M, Tsukamoto G, Matsuo R.
Area postrema mediates gastric motor response induced by apomorphine in rats.
Brain Research. 960: 122-131, 2003, PMID:12505664

安松啓子, 勝川秀夫, 重村憲徳, 吉田竜介, 二ノ宮裕三.
神経切断後の塩味情報システム再形成過程.
日本味と匂学会誌. 10: 389-392, 2003

重村憲徳, 川東由利子, 安松啓子, 吉田竜介, 二ノ宮裕三.
dpa(D-フェニルアラニン感受性)遺伝子セグメントのうま味感受性への関与.
日本味と匂学会誌. 10: 653-656, 2003

吉田竜介, 重村憲徳, 安松啓子, 二ノ宮裕三.
統計学的解析法による味刺激に対する味細胞の応答性の検討.
日本味と匂学会誌. 10: 659-662, 2003

吉田竜介, 長濱辰文.
カルシウムイメージング法を用いた摂食神経回路網の研究.
生物物理. 245: 15-20, 2003

Kobashi M, Furudono Y, Matsuo R, Yamamoto T.
Central orexin facilitates gastric relaxation and contractility in rats.
Nueroscience Letters. 332: 171-174, 2002, PMID:12399008

Funahashi M, Mitoh Y, Matsuo R.
Electrophysiological properties of the rat area postrema neurons displaying both the transient outward current and the hyperpolarization-activated inward current.
Brain Research Bulletin. 58: 337-343, 2002, PMID:12128161

Funahashi M, Mitoh Y, Matsuo R.
Two distinct types of transient outward currents in area postrema neurons in rat brain slices.
Brain Research. 942: 31-45, 2002, PMID:12031850

Kobashi M, Koga T, Mizutani M, Matsuo R.
Suppression of vagal motor activities evokes laryngeal afferent-mediated inhibition of gastric motility.
American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 282: R818-R827, 2002, PMID:11832403

Funahashi M, Matsuo R, Stewart M.
Long-term enhancement of excitatory synaptic inputs to layer V parahippocampal neurons by low frequency stimulation in rat brain slices.
Neuroscience Research. 42: 65-77, 2002, PMID:11814610

吉田竜介, 石塚智, 二ノ宮裕三.
単一味蕾への味刺激に対する味細胞応答の記録.
日本味と匂学会誌. 9: 507-510, 2002

安松啓子, 三浦裕仁, 吉田竜介, 日野明寛, 二ノ宮裕三.
味を感じる:神経メカニズム.
細胞工学. 21: 1429-1433, 2002

Yoshida R, Iwamoto A, Nagahama T.
Calcium imaging for detection and estimation of spike activities in Aplysia neurons.
Zoological Science. 18: 631-643, 2001