研究業績
2024年
Mikami A, Hyodo A, Horie K, Yasumatsu K, Ninomiya Y, Mitoh Y, Iida S,
Yoshida R.
The role of GABA in modulation of taste signaling within the taste
bud.
Pflugers Archiv, doi:10.1007/s00424-024-03007-x
PMID:
39210062
Yoshida R, Ninomiya Y.
Mechanisms and Functions of Sweet Reception in Oral and Extraoral
Organs.
International Journal of Molecular Sciences, 25:7398
doi:10.3390/ijms25137398 PMID:
39000505
Hyodo A, Mikami A, Horie K, Mitoh Y, Ninomiya Y, Iida S, Yoshida R.
Salivary buffering capacity is correlated with umami but not sour
taste sensitivity in healthy adult Japanese subjects
Archieves of Oral Biology,
165:106013.
doi:10.1016/j.archoralbio.2024.106013. PMID:
38833772
Nishitani T, Mitoh Y, Yajima T, Tachiya D, Hoshika T, Fukunaga T,
Nishitani Y, Yoshida R, Mizoguchi I, Ichikawa H, Sato T.
Distribution of alpha-synuclein in rat salivary glands
Anatomical Reports,
307(8):2933-2946. doi:10.1002/ar.25395.
PMID:
38284507
2023年
Yoshida R.
Sensory Systems for Sugar-Induced Cephalic Phase Insulin Release
Current Oral Health Reports, 10:117-123.
doi:10.1007/s40496-023-00347-y.
Takamori M, Mitoh Y, Horie K, Egusa M, Miyawaki T, Yoshida R.
Sugar signals from oral glucose transporters elicit cephalic-phase
insulin release in mice
Journal of Physiological Science, 73:16.
doi:10.1186/s12576-023-00875-3. PMID:
37525102
Iwata S, Yoshida R, Takai S, Sanematsu K, Shigemura N, Ninomiya Y.
Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via
T1R-Independent Sweet Taste Pathway.
Nutrients, 15:2941. doi:10.3390/nu15132941. PMID:
37447268
Yamase Y, Huang H, Mitoh Y, Egusa M, Miyawaki T, Yoshida R.
Taste Responses and Ingestive Behaviors to Ingredients of Fermented
Milk in Mice.
Foods, 12:1150 doi:10.3390/foods12061150. PMID:
36981077
Kobashi M, Shimatani Y, Fujita M.
Oxytocin increased intragastric pressure in the forestomach of rats
via the dorsal vagal complex.
Physiology and Behavior, 261:114087. doi:
10.1016/j.physbeh.2023.114087. PMID:
36646162
Kawabata Y, Takai S, Sanematsu K, Yoshida R, Kawabata F, Shigemura N.
The Antiarrhythmic Drug Flecainide Enhances Aversion to HCl in Mice.
eNeuro, 10:ENEURO.0048-23.2023 doi:
10.1523/ENEURO.0048-23.2023. PMID:
37696662
Yamada R, Tanaka Y, Sugimoto H*, Kodama N, Yoshida R, Minagi S.
Effect of continuous sweet gustatory stimulation on salivary flow rate
over time.
Archives of Oral Biology 146:105590.
doi:10.1016/j.archoralbio.2022.105590. PMID:
36463789
Yoshida R, Ninomiya Y.
Chapter 2: Umami and MSG.
Umami: Taste for Health, 2023, (Elsevier)
2022年
吉田竜介
味覚
歯科衛生士シリーズ:口腔解剖学・口腔組織発生学・口腔生理学 200-206
医
歯薬出版
吉田竜介
研究室紹介(岡山大学大学院医歯薬学総合研究科口腔生理学分野
日本味と匂学会誌 29: 113-116
2021年
Yoshida R, Yasumatsu K, Ninomiya Y.
The sweet taste receptor, glucose transporters, and the ATP-sensitive
K
+ (K
ATP) channel: Sugar sensing for the
regulation of energy homeostasis
Current Opinion in Physiology. 20:57-63
doi:10.1016/j.cophys.2021.01.009
Yoshida R, Margolskee RF, Ninomiya Y.
Phosphatidylinositol‐3 kinase mediates the sweet suppressive effect of
leptin in mouse taste cells.
Journal of Neurochemistry. 158:233-245, doi:10.1111/jnc.15268.
PMID:
33319361
2020年
Sato T, Yajima T, Fujita M, Kobashi M, Ichikawa H, Yoshida R, Mitoh Y.
Orexin A and B in the rat superior salivatory nucleus.
Autonomic Neuroscience. 228:102712, doi:
10.1016/j.autneu.2020.102712. PMID:
32721850
Yasumatsu K, Ohkuri T, Yoshida R, Iwata S, Margolskee RF, Ninomiya Y.
Sodium‐glucose cotransporter 1 as a sugar taste sensor in mouse
tongue.
Acta Physiologica. 230:e13529, doi: 10.1111/apha.13529. PMID:
32599649
Kobashi M, Shimatani Y, Fujita M, Mitoh Y, Yoshida R, Matsuo R.
The Effects of Mutual Interaction of Orexin-A and Glucagon-Like
Peptide-1 on Reflex Swallowing Induced by SLN Afferents in Rats.
International Journal of Molecular Sciences. 21:E4422, doi:
10.3390/ijms21124422. PMID:
32580304
Masamoto M, Mitoh Y, Kobashi M, Shigemura N, Yoshida R.
Effects of bitter receptor antagonists on behavioral lick responses of
mice.
Neuroscience letters. 730:135041, doi:
10.1016/j.neulet.2020.135041. PMID:
32413538
Yoshida R, Ninomiya Y.
Section 21: 3.10 - Sweet and Umami Taste
The Senses: A Comprehensive Reference, Reference Work, 2nd Edition,
2021 (Elsevier)
2019年
Takai S, Watanabe Y, Sanematsu K, Yoshida R, Margolskee RF, Jiang P,
Atsuta I, Koyano K, Ninomiya Y, Shigemura N.
Effects of insulin signaling on mouse taste cell proliferation.
PLoS One. 14:e0225190, doi: 10.1371/journal.pone.0225190. PMID:
31714935
Shigemura N, Takai S, Hirose F, Yoshida R, Sanematsu K, Ninomiya Y.
Expression of Renin-Angiotensin System Components in the Taste Organ
of Mice.
Nutrients. 11: E2251, 2019, doi: 10.3390/nu11092251, PMID:
31546789
Ohla K, Yoshida R, Roper SD, Di Lorenzo PM, Victor JD, Boughter Jr JD,
Fletcher M, Katz DB, Chaudhari N.
Recognizing taste: coding patterns along the neural axis in mammals.
Chemical Senses. 44: 237-247, 2019, doi: 10.1093/chemse/bjz013,
PMID:
30788507
吉田竜介, 實松敬介, 高井信吾, 岩田周介, 重村憲徳.
ヒト味覚認知閾値に対する低濃度塩添加の影響.
日本味と匂学会誌第53回大会Proceeding集. S35-S38, 2019
美藤純弘, 佐藤匡, 矢島健大, 藤田雅子, 小橋基, 市川博之, 吉田竜介.
摂食亢進ペプチドのラット顎下腺・舌下腺支配の副交感神経節前ニューロンに対する影響.
日本味と匂学会誌第53回大会Proceeding集. S55-S58, 2019
吉田竜介.
末梢味覚器におけるうま味のコーディング.
日本味と匂学会誌. 26: 71-76, 2019
吉田竜介.
末梢における味覚情報伝達.
岡山歯学会雑誌. 38: 25-36, 2019
2018年
Yoshida R, Takai S, Sanematsu K, Margolskee RF, Shigemura N, Ninomiya
Y.
Bitter Taste Responses of Gustducin-positive Taste Cells in Mouse
Fungiform and Circumvallate Papillae.
Neuroscience. 369: 29-39, 2018, PMID:
29113930
Matsuo R, Kobashi M, Fujita M.
Electrophysiological study on sensory nerve activity from the
submandibular salivary gland in rats.
Brain Research. 1680: 137-142, 2018, PMID:
29269052
2017年
Yoshida R, Shin M, Yasumatsu K, Takai S, Inoue M, Shigemura N,
Takiguchi S, Nakamura S, Ninomiya Y.
The Role of Cholecystokinin in Peripheral Taste Signaling in Mice.
Frontiers in Physiology. 8: 886. 2017, PMID:
29163209
Kobashi M, Mizutani S, Fujita M, Mitoh Y, Shimatani Y, Matsuo R.
Central glucagon like peptide-1 inhibits reflex swallowing elicited by
the superior laryngeal nerve via caudal brainstem in the rat.
Brain Research. 1671: 26-32. 2017, PMID:
28693820
Mitoh Y, Ueda H, Ichikawa H, Fujita M, Kobashi M, Matsuo R.
Effects of cevimeline on excitability of parasympathetic preganglionic
neurons in the superior salivatory nucleus of rats.
Autonomic Neuroscience. 206: 1-7. 2017, PMID:
28600120
岩田周介, 安松啓子, 井上真由子, 吉田竜介, 重村憲徳, 二ノ宮裕三.
アンジオテンシンIIのT1Rs非依存的甘味応答に及ぼす影響.
日本味と匂学会誌. 24: S31-S34, 2017
2016年
Jyotaki M, Sanematsu K, Shigemura N, Yoshida R, Ninomiya Y.
Leptin suppresses sweet taste responses of enteroendocrine STC-1
cells.
Neuroscience. 332: 76-87, 2016, PMID:
27353597
Sanematsu K, Kitagawa M, Yoshida R, Nirasawa S, Shigemura N, Ninomiya
Y.
Intracellular acidification is required for full activation of the
sweet taste receptor by miraculin.
Scientific Reports. 6: 22807, 2016, PMID:
26960429
Yoshida R, Ninomiya Y.
Taste information derived from T1R-expressing taste cells in mice.
Biochemical Journal. 473: 525-536, 2016, PMID:
26912569
Takai S, Yoshida R, Yasumatsu K, Shigemura N, Ninomiya Y.
The function of glucagon-like peptide-1 in the mouse peripheral taste
system.
Journal of Oral Bioscience. 58: 10-15, 2016
吉田竜介, 二ノ宮裕三.
甘味受容体を起点とした口腔脳腸の味情報−内分泌連関と食調節.
食品加工技術. 36: 30-38, 2016
美藤純弘, 藤田雅子, 小橋基, 松尾龍二.
前脳による唾液分泌の調節.
日本歯科評論. 76: 145-150, 2016
2015年
Yoshida R, Noguchi K, Shigemura N, Jyotaki M, Takahashi I, Margolskee
RF, Ninomiya Y.
Leptin Suppresses Mouse Taste Cell Responses to Sweet Compounds.
Diabetes. 64: 3751-3762, 2015, PMID:
26116698
Niki M, Jyotaki M, Yoshida R, Yasumatsu K, Shigemura N, DiPatrizio NV,
Piomelli D, Ninomiya Y.
Modulation of sweet taste sensitivities by endogenous leptin and
endocannabinoids in mice.
Journal of Physiology. 593: 2527-2545, 2015, PMID:
25728242
Takai S, Yasumatsu K, Inoue M, Iwata S, Yoshida R, Shigemura N,
Yanagawa Y, Drucker DJ, Margolskee RF, Ninomiya Y.
Glucagon-like peptide-1 is specifically involved in sweet taste
transmission.
FASEB Journal. 29: 2268-2280, 2015, PMID:
25678625
Yasumatsu K, Manabe T, Yoshida R, Iwatsuki K, Uneyama H, Takahashi I,
Ninomiya Y.
Involvement of multiple taste receptors in umami taste: analysis of
gustatory nerve responses in metabotropic glutamate receptor 4
knockout mice.
Journal of Physiology. 593: 1021-1034, 2015, PMID:
25529865
Matsuo R, Kobashi M, Mitoh Y, Fujita M.
Role of the lateral hypothalamus in submandibular salivary secretion
during feeding in rats.
Brain Research. 1596: 99-107, 2015, PMID:
25446459
2014年
Sanematsu K, Yoshida R, Shigemura N, Ninomiya Y.
Structure, function, and signaling of taste G-protein-coupled
receptors.
Current Pharmaceutical Biotechnology. 15: 951-61, 2014, PMID:
25248559
Iwata S, Yoshida R, Ninomiya Y.
Taste transductions in taste receptor cells: basic tastes and
moreover.
Current Pharmaceutical Design. 20: 2684-92, 2014, PMID:
23886388
Kobashi M, Mizutani S, Fujita M, Mitoh Y, Shimatani Y, Matsuo R.
Central orexin inhibits reflex swallowing elicited by the superior
laryngeal nerve via caudal brainstem in the rat.
Physiology and Behavier. 130: 6-12, 2014, PMID:
24637063
Maeda N, Kobashi M, Mitoh Y, Fujita M, Minagi S, Matsuo R.
Differential involvement of two cortical masticatory areas in
submandibular salivary secretion in rats.
Brain Research. 1543: 200-208, 2014, PMID:
24309141
高井信吾, 安松啓子, 吉田竜介, 重村憲徳, 二ノ宮裕三.
味神経に発現するGLP-1レセプターとその役割.
日本味と匂学会誌. 21: 253-256, 2014
岩田周介, 吉田竜介, 重村憲徳, 二ノ宮裕三.
アンギオテンシンIIによるエンドカンナビノイド受容体を介した甘味の増強.
日本味と匂学会誌. 21: 259-262, 2014
2013年
Shigemura N, Iwata S, Yasumatsu K, Ohkuri T, Horio N, Sanematsu K,
Yoshida R, Margolskee RF, Ninomiya Y.
Angiotensin II Modulates Salty and Sweet Taste Sensitivities.
Journal of Neuroscience. 33: 6267-6277, 2013, PMID:
23575826
Kusuhara Y, Yoshida R, Ohkuri T, Yasumatsu K, Voigt A, H?bner S, Maeda
K, Boehm U, Meyerhof W, Ninomiya Y.
Taste responses in mice lacking taste receptor subunit T1R1.
Journal of Physiology. 591: 1967-1985, 2013, PMID:
23339178
Yoshida R, Niki M, Jyotaki M, Sanematsu K, Shigemura N, Ninomiya Y.
Modulation of sweet responses of taste receptor cells.
Seminars in Cell & Developmental Biology. 24: 226-231,
2013, PMID:
22947916
吉田竜介, 二ノ宮裕三.
味細胞における味の伝達機構.
JOHNS. 29: 13-15, 2013
2012年
Yasumatsu K, Ogiwara Y, Takai S, Yoshida R, Iwatsuki K, Torii K,
Margolskee RF, Ninomiya Y.
Umami taste in mice uses multiple receptors and transduction pathways.
Journal of Physiology. 590: 1155-1170, 2012, PMID:
22183726
Yoshida R.
Hormones and bioactive substances that affect peripheral taste
sensitivity.
Journal of Oral Bioscience. 54: 67-72, 2012
吉田竜介, 二ノ宮裕三.
食欲調節物質による甘味感受性の調節.
日本薬理学会雑誌. 139: 131, 2012
2011年
Niki M, Takai S, Kusuhara Y, Ninomiya Y, Yoshida R.
Responses to apical and basolateral application of glutamate in mouse
fungiform taste cells with action potentials.
Cellular and Molecular Neurobiology. 31: 1033-1040, 2011, PMID:
21573975
Horio N, Yoshida R, Yasumatsu K, Yanagawa Y, Ishimaru Y, Matsunami H,
Ninomiya Y.
Sour Taste Responses in Mice Lacking PKD Channels.
PLoS ONE. 6: e20007, 2011, PMID:
21625513
Ueda H, Mitoh Y, Fujita M, Kobashi M, Yamashiro T, Sugimoto T,
Ichikawa H, Matsuo R.
Muscarinic receptor immunoreactivity in the superior salivatory
nucleus neurons innervating the salivary glands of the rat.
Neuroscience Letters. 499: 42-46, 2011, PMID:
21624431
仁木麻由, 上瀧将史, 吉田竜介, 二ノ宮裕三.
レプチン受容体アンタゴニストによるマウスの甘味応答.
日本味と匂学会誌. 18: 255-259, 2011
2010年以前
Murata Y, Yasuo T, Yoshida R, Obata K, Yanagawa Y, Margolskee RF,
Ninomiya Y.
Action potential-enhanced ATP release from taste cells through
hemichannels.
Journal of Neurophysiology. 104: 896-901, 2010, PMID:
20519578
Cartoni C, Yasumatsu K, Ohkuri T, Shigemura N, Yoshida R, Godinot N,
le Coutre J, Ninomiya Y, Damak S.
Taste preference for fatty acids is mediated by GPR40 and GPR120.
Journal of Neuroscience. 30: 8376-8382, 2010, PMID:
20573884
Yoshida R, Ohkuri T, Jyotaki M, Yasuo T, Horio N, Yasumatsu K,
Sanematsu K, Shigemura N, Yamamoto T, Margolskee RF, Ninomiya Y.
Endocannabinoids selectively enhance sweet taste.
Proceedings of National Academy of Sciences of the United States of
America. 107: 935-939, 2010, PMID:
20080779
Yoshida R, Niki M, Murata Y, Shigemura N, Ninomiya Y.
Reception and transmission of taste information in Type II and Type
III taste bud cells.
Journal of Oral Bioscience. 52: 358-364, 2010
Niki M, Yoshida R, Takai S, Ninomiya Y.
Gustatory Signaling in the Periphery: Detection, Transmission, and
Modulation of Taste Information.
Biological & Pharmaceutical Bulletin. 33: 1772-1777, 2010,
PMID:
21048297
Niki M, Jyotaki M, Yoshida R, Ninomiya Y.
Reciprocal modulation of sweet taste by leptin and endocannabinoids.
Results and Problems in Cell Differentiation. 52: 101-114,
2010, PMID:
20865375
Yoshida R, Ninomiya Y.
New Insights into the Signal Transmission from Taste Cells to
Gustatory Nerve Fibers.
International Review of Cell and Molecular Biology. 279:
101-134, 2010, PMID:
20797678
Horio N, Jyotaki M, Yoshida R, Sanematsu K, Shigemura N, Ninomiya Y.
New frontiers in gut nutrient sensor research: nutrient sensors in the
gastrointestinal tract: modulation of sweet taste sensitivity by
leptin.
Journal of Pharmacological Sciences. 112: 8-12, 2010, PMID:
20093782
Kobashi M, Xuan SY, Fujita M, Mitoh Y, Matsuo R.
Central ghrelin inhibits reflex swallowing elicited by activation of
the superior laryngeal nerve in the rat.
Regulatory Peptides. 160: 19-25, 2010, PMID:
20045031
安尾敏明, 吉田竜介, 柳川右千夫, Margolskee RF, 二ノ宮裕三.
マウス味細胞の味応答時におけるGABAの作用.
日本味と匂学会誌. 17: 227-230, 2010
仁木麻由, 大栗弾宏, 上瀧将史, 吉田竜介, 二ノ宮裕三.
エンドカンナビノイド受容体アンタゴニストによるdb/dbマウスにおける甘味応答抑制.
日本味と匂学会誌. 17: 231-234, 2010
吉田竜介, 大栗弾宏, 重村憲徳, 二ノ宮裕三.
内因性カンナビノイドの甘味増強作用.
実験医学. 28: 1405-1408, 2010
吉田竜介, 仁木麻由, 二ノ宮裕三.
末梢における味覚受容・情報伝達とその調節.
Clinical Neuroscience. 28: 1227-1231, 2010
Yoshida R, Miyauchi A, Yasuo T, Jyotaki M, Murata Y, Yasumatsu K,
Shigemura N, Yanagawa Y, Obata K, Ueno H, Margolskee RF, Ninomiya Y.
Discrimination of taste qualities among mouse fungiform taste bud
cells.
Journal of Physiology. 587: 4425-4439, 2009, PMID:
19622604
Yoshida R, Horio N, Murata Y, Yausmatsu K, Shigemura N, Ninomiya Y.
NaCl responsive taste cells in the mouse fungiform taste buds.
Neuroscience. 159: 795-803, 2009, PMID:
19167465
Shigemura N, Shirosaki S, Sanematsu K, Yoshida R, Ninomiya Y.
Genetic and molecular basis of individual differences in human umami
taste perception.
PLoS ONE. 4: e6717, 2009, PMID:
19696921
Yoshida R, Yasumatsu K, Shirosaki S, Jyotaki M, Horio N, Murata Y,
Shigemura N, Nakashima K, Ninomiya Y.
Multiple receptor systems for umami taste in mice.
Annals of the New York Academy of Sciences. 1170: 51-54, 2009,
PMID:
19686107
Sanematsu K, Horio N, Murata Y, Yoshida R, Ohkuri T, Shigemura N,
Ninomiya Y.
Modulation and transmission of sweet taste information for energy
homeostasis.
Annals of the New York Academy of Sciences. 1170: 102-106,
2009, PMID:
19686118
Yasumatsu K, Horio N, Murata Y, Ohkuri T, Yoshida R, Ninomiya Y.
Multiple receptors and transduction underlie umami taste reception in
mice.
American Journal of Clinical Nutrition. 90: 747S-752S, 2009,
PMID:
19571210
Shigemura N, Shirosaki S, Ohkuri T, Sanematsu K, Islam AS, Ogiwara Y,
Kawai M, Yoshida R, Ninomiya Y.
Postnatal development of inhibitory synaptic transmission to superior
salivatory neurons in rats.
American Journal of Clinical Nutrition. 90: 764S-769S, 2009,
PMID:
19625681
Kobashi M, Yanagihara M, Fujita M, Mitoh Y, Matsuo R.
Fourth ventricular administration of ghrelin induces relaxation of the
proximal stomach in the rat.
American Journal of Physiology, Regulatory, Integrative and
Comparative Physiology. 296: R217-R223, 2009, PMID:
19036830
Mitoh Y, Funahashi M, Fujita M, Kobashi M, Matsuo R.
Variation in umami perception and in candidate genes for the umami
receptor in mice and humans.
Journal of Medical Investigation. 56: Suppl270-272, 2009, PMID:
20224199
Ueda H, Mitoh Y, Ichikawa H, Kobashi M, Yamashiro T, Matsuo R.
Cevimeline enhances the excitability of rat superior salivatory
neurons.
Journal of Medical Investigation. 56: Suppl267-269, 2009, PMID:
20224198
Matsushima A, Ichikawa H, Fujita M, Mitoh Y, Kobashi M, Yamashiro T,
Matsuo R.
Immunohistochemical study on the distribution and origin of GABAergic
nerve terminals in the superior salivatory nucleus.
Journal of Medical Investigation. 56: Suppl264-266, 2009, PMID:
20224197
安尾敏明, 吉田竜介, 堀尾奈央, 重村憲徳, 二ノ宮裕三.
マウス味細胞におけるGABAの機能解析.
日本味と匂学会誌. 16: 323-326, 2009
吉田竜介, 二ノ宮裕三.
味覚情報のコーディングにおける味細胞の役割.
日本味と匂学会誌. 16: 117-124, 2009
Taravera K, Yasumatsu K, Yoshida R, Margolskee RF, Voets T, Ninomiya
Y, Nilius B.
The taste transduction channel TRPM5 is a locus for bitter-sweet taste
interactions.
FASEB Journal. 22: 1343-1355, 2008, PMID:
18070821
Shigemura N, Ohkuri T, Sadamitsu C, Yasumatsu K, Yoshida R, Beauchamp
GK, Bachmanov AA, Ninomiya Y.
Amiloride-sensitive NaCl taste responses are associated with genetic
variation of ENaC alpha-subunit in mice.
American Journal of Physiology-Regulatory Integrative and
Comparative Physiology. 294: R66-75, 2008, PMID:
17977920
Mitoh Y, Funahashi M, Fujii A, Fujita M, Kobashi M, Matsuo R.
Development of inhibitory synaptic transmission to the superior
salivatory nucleus in rats.
Brain Research. 1191: 47-54, 2008, PMID:
18155184
吉田竜介, 村田芳博, 安尾敏明, 上瀧将史, 柳川右千夫, 小幡邦彦, 植野洋志, Margolskee RF, 二ノ宮裕三.
味細胞の細胞型と応答特性.
日本味と匂学会誌. 15: 285-288, 2008
城崎慎也, 川東由利子, 中島清人, 重村憲徳, 安松啓子, 吉田竜介, Margolskee RF, 二ノ宮裕三.
mGluRアンタゴニスト混合うま味溶液に対するT1r3-KOおよびC57BL/6マウスの行動学的解析.
日本味と匂学会誌. 15: 293-296, 2008
村田芳博, 吉田竜介, 安尾敏明, 柳川右千夫, 小幡邦彦, 植野洋志, Margolskee RF, 二ノ宮裕三.
マウスII型味細胞の発火頻度依存性ATP放出.
日本味と匂学会誌. 15: 381-384, 2008
Hisatsune C, Yasumatsu K, Takahashi-Iwanaga H, Ogawa N, Kuroda Y,
Yoshida R, Ninomiya Y, Mikoshiba K.
Abnormal taste perception in mice lacking the type 3 inositol
1,4,5-triphosphate receptor.
Journal of Biological Chemistry. 282: 37225-37231, 2007, PMID:
17925404
Kodama N, Funahashi M, Mitoh Y, Minagi S, Matsuo R.
Purinergic modulation of area postrema neuronal excitability in rat
brain slices.
Brain Research. 1165: 50-59, 2007, PMID:
17658494
城崎慎也, 川東由利子, 中島清人, 重村憲徳, 安松啓子, 吉田竜介, Margolskee RF, 二ノ宮裕三.
T1R3-KOマウスにおけるうま味物質に対する条件付け味覚嫌悪学習.
日本味と匂学会誌. 14: 379-382, 2007
安松啓子, 大栗弾宏, 吉田竜介, Damak S, Margolskee RF, 二ノ宮裕三.
塩味、酸味、苦味物質混合によるマウス鼓索神経甘味応答の修飾.
日本味と匂学会誌. 14: 387-390, 2007
村田芳博, 安尾敏明, 吉田竜介, 二ノ宮裕三.
マウス茸状乳頭味細胞のATP放出.
日本味と匂学会誌. 14: 391-394, 2007
吉田竜介, 安尾敏明, 村田芳博, 上瀧将史, 二ノ宮裕三.
単一細胞応答の観点からみたマウス茸状乳頭味蕾の応答性.
日本味と匂学会誌. 14: 395-398, 2007
吉田竜介, 安松啓子, 二ノ宮裕三.
活動電位を発生する味細胞は味覚情報伝達経路の起始点となりうる.
日本味と匂学会誌. 14: 163-170, 2007
重村憲徳, 安松啓子, 吉田竜介, 二ノ宮裕三.
甘味感受性に影響する温度依存的なTrpm5の働き.
低温生物工学会誌. 53: 53-55, 2007
Yoshida R, Shigemura N, Sanematsu K, Yasumatsu K, Ishizuka S, Ninomiya
Y.
Taste responsiveness of fungiform taste cells with action potentials.
Journal of Neurophysiology. 96: 3088-3095, 2006, PMID:
16971686
Ohkuri T, Yasumatsu K, Shigemura N, Yoshida R, Ninomiya Y.
Amiloride inhibition on NaCl responses of the Chorda Tympani nerve in
two 129 strains of mice, 129P3/J and 129X1/SvJ.
Chemical Senses. 31: 565-572, 2006
Damak S, Rong M, Yasumatsu K, Kokrashvili Z, Perez CA, Shigemura N,
Yoshida R, Mosinger B Jr, Glendinning JI, Ninomiya Y, Margolskee RF.
Trpm5 null mice respond to bitter, sweet and umami compounds.
Chemical Senses. 31: 253-264, 2006, PMID:
16436689
Yoshida R, Yasumatsu K, Shigemura N, Ninomiya Y.
Coding channels for taste perception: information transmission from
taste cells to gustatory nerve fibers.
Archives of Histology and Cytology. 69: 233-242, 2006, PMID:
17287578
Funahashi M, Mitoh Y, Akaike T, Matsuo R.
Variety of morphological and electrophysiological properties of area
postrema neurons in adult rat brain slices.
Neuroscience Research. 54: 43-48, 2006, PMID:
16293330
Kobashi M, Shimatani Y, Shirota K, Xuan SY, Mitoh Y, Matsuo R.
Variety of morphological and electrophysiological properties of area
postrema neurons in adult rat brain slices.
American Journal of Physiology-Regulatory Integrative and
Comparative Physiology. 290: R290-R297, 2006, PMID:
16195495
大倉哲也, 安松啓子, 伊藤由美子, 吉田竜介, 河合崇行, 日下部裕子, 進藤洋一郎, 日野明寛, 二ノ宮裕三.
塩味代替物・増強物質の利用による塩味受容機構の解析.
日本味と匂学会誌. 13: 279-280, 2006
安松啓子, 吉田竜介, 重村憲徳, Damak S, Margolskee RF, 二ノ宮裕三.
T1r3-KO、TRPM5-KOマウス鼓索神経におけるうま味応答神経線維の解析.
日本味と匂学会誌. 13: 335-338, 2006
大栗弾宏, 安松啓子, 吉田竜介, 重村憲徳, 二ノ宮裕三.
C57BL/6NとBALB/cマウスの鼓索神経甘味応答の刺激温度による変化.
日本味と匂学会誌. 13: 339-342, 2006
實松啓介, 安松啓子, 吉田竜介, 重村憲徳, 二ノ宮裕三.
Tas1r3遺伝子型とグルマリン感受性の関連.
日本味と匂学会誌. 13: 343-346, 2006
城崎慎也, 重村憲徳, 吉田竜介, 安松啓子, Margolskee RF, 二ノ宮裕三.
T1r3-KOマウスの甘味物質に対する行動応答解析.
日本味と匂学会誌. 13: 347-350, 2006
吉田竜介, 大栗弾宏, 安松啓子, 重村憲徳, 二ノ宮裕三.
マウス茸状乳頭味細胞のNaCl応答:アミロライド感受性細胞と非感受性細胞.
日本味と匂学会誌. 13: 351-354, 2006
重村憲徳, 大栗弾宏, 貞光千春, 安松啓子, 吉田竜介, Bachmanov AA, Beauchamp GK, 二ノ宮裕三.
ENaC遺伝子多型性とアミロライド感受性との相関.
日本味と匂学会誌. 13: 351-354, 2006
重村憲徳, 太田理絵, 杉田大悟, 山田礼子, 吉田竜介, 安松啓子, 二ノ宮裕三.
口は食べ物認識の見張り役.
歯界展望. 107: 597-602, 2006
Shigemura N, Islam AA, Sadamitsu C, Yoshida R, Yasumatsu K, Ninomiya
Y.
Expression of amiloride-sensitive epithelial sodium channels in mouse
taste cells after chorda tympani nerve crush.
Chemical Senses. 30: 531-538, 2005, PMID:
16030075
Sanematsu K, Yasumatsu K, Yoshida R, Shigemura N, Ninomiya Y.
Mouse strain differences in Gurmarin-sensitivity of sweet taste
responses are not associated with polymorphisms of the sweet receptor
gene, Tas1r3.
Chemical Senses. 30: 491-496, 2005, PMID:
15932937
Yoshida R, Sanematsu K, Shigemura N, Yasumatsu K, Ninomiya Y.
Taste receptor cells responding with action potentials to taste
stimuli and their molecular expression of taste related genes.
Chemical Senses. 30: i19-20, 2005, PMID:
15738107
Yasumatsu K, Shigemura N, Yoshida R, Ninomiya Y.
Recovery of salt responses and PGP 9.5 immunoreactive taste bud cells
during regeneration of the mouse chorda tympani nerve.
Chemical Senses. 30: i62-i63, 2005, PMID:
157381975
Shigemura N, Yasumatsu K, Yoshida R, Sako N, Katsukawa H, Nakashima K,
Imoto T, Ninomiya Y.
The role of the
dpa locus in mice.
Chemical Senses. 30: i84-i85, 2005, PMID:
15738208
Kohjitani A, Funahashi M, Miyawaki T, Hanazaki M, Matsuo R, Shimada M.
Peripheral N-methyl-D-aspartate receptors modulate nonadrenergic
noncholinergic lower esophageal sphincter relaxation in rabbits.
Anesthesia and Analgesia. 10: 1681-1688, 2005, PMID:
16301241
Kobashi M, Ichikawa H, Kobashi M, Funahashi M, Mitoh Y, Matsuo R.
The origin of sensory nerve fibers that innervate the submandibular
salivary gland in the rat.
Braain Research. 1060: 184-187, 2005, PMID:
16188241
Kobashi M, Koga T, Mizutani M, Matsuo R.
Neural mechanism and possible role of inhibition of gastric motility
induced by superior laryngeal afferents.
Chemical Senses. 30: i72-i73, 2005, PMID:
15738202
吉田竜介, 重村憲徳, 安松啓子, 二ノ宮裕三.
脳へ味を伝える:味のニューラルコーディングチャネルの形成.
日本味と匂学会誌. 12: 259-262, 2005
城崎慎也, 重村憲徳, 吉田竜介, 安松啓子, Margolskee RF, 二ノ宮裕三.
TRPM5-KOマウスのキニーネに対する行動応答の解析.
日本味と匂学会誌. 12: 373-376, 2005
吉田竜介, 重村憲徳, 安松啓子, 二ノ宮裕三.
レプチンによる甘味感受性の修飾.
生体の科学. 56: 109-113, 2005
Funahashi M, Mitoh Y, Matsuo R.
Nicotinic modulation of area postrema neuronal excitability in rat
brain slices.
Brain Research. 1017: 227-233, 2004, PMID:
15261119
Funahashi M, Mitoh Y, Matsuo R.
The sensitivity of hyperpolarization-activated cation current (Ih) to
propofol in rat area postrema neurons.
Brain Research. 1015: 198-201, 2004, PMID:
15223387
Mitoh Y, Funahashi M, Kobashi M, Matsuo R.
Excitatory and inhibitory postsynaptic currents of the superior
salivatory nucleus innervating the salivary glands and tongue in the
rat.
Brain Research. 999: 62-72, 2004, PMID:
14746922
Yoshida R, Nagahama T.
Search for cerebral G cluster neurons responding to taste stimulation
with seaweed in
Aplysia kurodai by the use of calcium imaging.
Journal of Neurobiology. 55: 299-314, 2003, PMID:
12717700
Funahashi M, Mitoh Y, Kohjitani A, Matsuo R.
Role of the hyperpolarization-activated cation current (Ih) in
pacemaker activity in area postrema neurons of rat brain slices.
Journal of Physiology. 552: 135-148, 2003, PMID:
12897173
Higuchi H, Funahashi M, Miyawaki T, Mitoh Y, Kohjitani A, Shimada M,
Matsuo R.
Suppression of the hyperpolarization-activated inward current
contributes to the inhibitory actions of propofol on rat CA1 and CA3
pyramidal neurons.
Neuroscience Research. 45: 459-472, 2003, PMID:
12657459
Kohjitani A, Miyawaki T, Funahashi M, Mitoh Y, Matsuo R, Shimada M.
Mexiletine inhibits nonadrenergic noncholinergic lower oesophageal
sphincter relaxation in rabbits.
Europian Journal of Pharmacology. 465: 145-151, 2003, PMID:
12650844
Kohjitani A, Miyawaki T, Funahashi M, Higuchi H, Matsuo R, Shimada M.
Ketamine and midazolam differentially inhibit nonadrenergic
noncholinergic lower esophageal sphincter relaxation in rabbits: role
of superoxide anion and nitric oxide synthase.
Anesthesiology. 98: 449-458, 2003, PMID:
12552205
Koga T, Kobashi M, Mizutani M, Tsukamoto G, Matsuo R.
Area postrema mediates gastric motor response induced by apomorphine
in rats.
Brain Research. 960: 122-131, 2003, PMID:
12505664
安松啓子, 勝川秀夫, 重村憲徳, 吉田竜介, 二ノ宮裕三.
神経切断後の塩味情報システム再形成過程.
日本味と匂学会誌. 10: 389-392, 2003
重村憲徳, 川東由利子, 安松啓子, 吉田竜介, 二ノ宮裕三.
dpa(D-フェニルアラニン感受性)遺伝子セグメントのうま味感受性への関与.
日本味と匂学会誌. 10: 653-656, 2003
吉田竜介, 重村憲徳, 安松啓子, 二ノ宮裕三.
統計学的解析法による味刺激に対する味細胞の応答性の検討.
日本味と匂学会誌. 10: 659-662, 2003
吉田竜介, 長濱辰文.
カルシウムイメージング法を用いた摂食神経回路網の研究.
生物物理. 245: 15-20, 2003
Kobashi M, Furudono Y, Matsuo R, Yamamoto T.
Central orexin facilitates gastric relaxation and contractility in
rats.
Nueroscience Letters. 332: 171-174, 2002, PMID:
12399008
Funahashi M, Mitoh Y, Matsuo R.
Electrophysiological properties of the rat area postrema neurons
displaying both the transient outward current and the
hyperpolarization-activated inward current.
Brain Research Bulletin. 58: 337-343, 2002, PMID:
12128161
Funahashi M, Mitoh Y, Matsuo R.
Two distinct types of transient outward currents in area postrema
neurons in rat brain slices.
Brain Research. 942: 31-45, 2002, PMID:
12031850
Kobashi M, Koga T, Mizutani M, Matsuo R.
Suppression of vagal motor activities evokes laryngeal
afferent-mediated inhibition of gastric motility.
American Journal of Physiology-Regulatory Integrative and
Comparative Physiology. 282: R818-R827, 2002, PMID:
11832403
Funahashi M, Matsuo R, Stewart M.
Long-term enhancement of excitatory synaptic inputs to layer V
parahippocampal neurons by low frequency stimulation in rat brain
slices.
Neuroscience Research. 42: 65-77, 2002, PMID:
11814610
吉田竜介, 石塚智, 二ノ宮裕三.
単一味蕾への味刺激に対する味細胞応答の記録.
日本味と匂学会誌. 9: 507-510, 2002
安松啓子, 三浦裕仁, 吉田竜介, 日野明寛, 二ノ宮裕三.
味を感じる:神経メカニズム.
細胞工学. 21: 1429-1433, 2002
Yoshida R, Iwamoto A, Nagahama T.
Calcium imaging for detection and estimation of spike activities in
Aplysia
neurons.
Zoological Science. 18: 631-643, 2001